(104 nodes) Mixed, incl. Class I MHC mediated antigen processing & presentation, and Protein modification by small protein conjugation or removal network (Giardia lamblia ATCC 50803)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GL50803_27059	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (273 aa)
	GL50803_6342	Protein 21.1. (1287 aa)
	GL50803_88071	Protein 21.1. (723 aa)
	GL50803_6589	Protein 21.1. (931 aa)
	GL50803_115444	Uncharacterized protein. (169 aa)
	GL50803_7950	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (390 aa)
	GL50803_15162	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	GL50803_17585	Protein 21.1. (718 aa)
	GL50803_11930	Retinoic acid induced 17-like protein. (648 aa)
	GL50803_17288	Protein 21.1. (1850 aa)
	GL50803_16533	Protein 21.1. (933 aa)
	GL50803_13127	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (254 aa)
	GL50803_8432	APC11, cyclin metabolism. (83 aa)
	GL50803_8241	HRT1-like protein. (89 aa)
	GL50803_10261	SP-RING-type domain-containing protein. (515 aa)
	GL50803_5921	Ubiquitin-conjugating enzyme E2-28.4 kDa. (324 aa)
	GL50803_91643	26S proteasome regulatory subunit, putative. (1348 aa)
	GL50803_9116	Kinase, CMGC GSK. (370 aa)
	GL50803_11165	Protein 21.1. (748 aa)
	GL50803_10410	Protein 21.1. (221 aa)
	GL50803_3171	UBCE14; Belongs to the ubiquitin-conjugating enzyme family. (164 aa)
	GL50803_8389	P60 katanin. (501 aa)
	GL50803_3978	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	GL50803_9155	Ribonuclease. (552 aa)
	GL50803_21331	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (401 aa)
	GL50803_13777	Cell division control protein 48. (717 aa)
	GL50803_31576	Ubiquitin-conjugating enzyme E2-21.2 kDa; Belongs to the ubiquitin-conjugating enzyme family. (204 aa)
	GL50803_24425	DUF862 domain-containing protein. (478 aa)
	GL50803_10661	Ubiquitin-conjugating enzyme E1. (1092 aa)
	GL50803_13427	Protein 21.1. (252 aa)
	GL50803_11434	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (250 aa)
	GL50803_7373	Protein 21.1. (1561 aa)
	GL50803_10361	P60 katanin. (648 aa)
	GL50803_4083	Ubiquitin-conjugating enzyme E1. (380 aa)
	GL50803_15270	Ubiquitin protein, putative. (498 aa)
	GL50803_15126	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (209 aa)
	GL50803_6288	Ubiquitin-activating enzyme E1 1. (537 aa)
	GL50803_6524	Ubiquitin-conjugating enzyme E2-28.4 kDa. (177 aa)
	GL50803_15030	Protein 21.1. (249 aa)
	GL50803_7760	Sentrin. (102 aa)
	GL50803_5142	Kinase, NEK. (987 aa)
	GL50803_14480	Protein 21.1. (1037 aa)
	GL50803_86683	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (510 aa)
	GL50803_94658	UN_NPL4 domain-containing protein. (527 aa)
	GL50803_16823	Non ATPase subunit MPR1 of 26S proteasome. (334 aa)
	GL50803_7962	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (255 aa)
	GL50803_9824	Proteasome subunit beta type 9. (221 aa)
	GL50803_11486	20S proteasome alpha subunit 7. (292 aa)
	GL50803_27027	WD_REPEATS_REGION domain-containing protein. (653 aa)
	GL50803_95918	E3 ubiquitin protein ligase. (670 aa)
	GL50803_27543	Uncharacterized protein. (221 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (509 aa)
	GL50803_1995	Proteasome subunit beta; Belongs to the peptidase T1B family. (217 aa)
	GL50803_14241	Uncharacterized protein. (1367 aa)
	GL50803_21622	RING-type domain-containing protein. (2073 aa)
	GL50803_16549	Uridine kinase. (682 aa)
	GL50803_7110	Ubiquitin. (82 aa)
	GL50803_17106	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (401 aa)
	GL50803_3209	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (209 aa)
	GL50803_17329	RING-type domain-containing protein. (374 aa)
	GL50803_3994	Ubiquitin fusion degradation protein 1. (313 aa)
	GL50803_16929	Uncharacterized protein. (523 aa)
	GL50803_10219	Protein 21.1. (1430 aa)
	GL50803_9850	RING-type domain-containing protein. (307 aa)
	GL50803_8189	Ubiquitin carboxyl-terminal hydrolase 14; Belongs to the peptidase C19 family. (459 aa)
	GL50803_2980	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (245 aa)
	GL50803_4365	26S protease regulatory subunit 6A. (501 aa)
	GL50803_33166	26S proteasome non-ATPase regulatory subunit 2. (1232 aa)
	GL50803_14785	Socius. (493 aa)
	GL50803_8843	Ubiquitin. (76 aa)
	GL50803_17053	Protein 21.1. (1044 aa)
	GL50803_16298	Ribosomal_S27 domain-containing protein. (137 aa)
	GL50803_16924	20S proteasome alpha subunit 1. (247 aa)
	GL50803_13756	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (207 aa)
	GL50803_15604	Uncharacterized protein. (259 aa)
	GL50803_16659	PCI domain-containing protein. (414 aa)
	GL50803_8638	Ubiquitin-conjugating enzyme E2-28.4 kDa. (161 aa)
	GL50803_12949	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (294 aa)
	GL50803_12950	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (196 aa)
	GL50803_15099	Proteasome subunit alpha type. (214 aa)
	GL50803_17152	Protein 21.1. (669 aa)
	GL50803_7896	26S proteasome non-ATPase regulatory subunit 7. (286 aa)
	GL50803_16065	Uncharacterized protein. (754 aa)
	GL50803_3279	Ribonuclease. (313 aa)
	GL50803_16843	Protein 21.1. (1252 aa)
	GL50803_4846	Protein 21.1. (765 aa)
	GL50803_12885	Uncharacterized protein. (398 aa)
	GL50803_8731	Zinc finger domain protein. (209 aa)
	GL50803_27055	Ubiquitin-conjugating enzyme E2-17 kDa 3. (145 aa)
	GL50803_16867	AAA family ATPase. (870 aa)
	GL50803_24068	UBC3; Belongs to the ubiquitin-conjugating enzyme family. (192 aa)
	GL50803_41369	Protein 21.1. (656 aa)
	GL50803_2876	UBC2, putative; Belongs to the ubiquitin-conjugating enzyme family. (172 aa)
	GL50803_17625	Kinase, CMGC GSK. (350 aa)
	GL50803_5665	Ubiquitin/ribosomal protein CEP52. (127 aa)
	GL50803_21233	RING-type domain-containing protein. (319 aa)
	GL50803_34160	RING-type domain-containing protein. (292 aa)
	GL50803_8217	Uridine kinase. (582 aa)
	GL50803_4331	26S proteasome non-ATPase regulatory subunit 6. (408 aa)
	GL50803_114192	Kinase, NEK. (1067 aa)
	GL50803_4897	Uncharacterized protein. (320 aa)
	GL50803_6563	Uracil phosphoribosyltransferase. (211 aa)
	GL50803_14497	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (244 aa)
	GL50803_113554	26S proteasome ATPase subunit S4, putative; Belongs to the AAA ATPase family. (447 aa)

Your Current Organism:

Giardia lamblia ATCC 50803

NCBI taxonomy Id: 184922
Other names: G. lamblia ATCC 50803, Giardia intestinalis ATCC 50803

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GL50803_10261	GL50803_12950	A8B6W7	A8BS74	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.541
GL50803_10261	GL50803_15162	A8B6W7	A8B4A9	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.541
GL50803_10261	GL50803_15270	A8B6W7	A8BD41	SP-RING-type domain-containing protein.	Ubiquitin protein, putative.	0.458
GL50803_10261	GL50803_16298	A8B6W7	A8BNY1	SP-RING-type domain-containing protein.	Ribosomal_S27 domain-containing protein.	0.544
GL50803_10261	GL50803_24068	A8B6W7	A8BV55	SP-RING-type domain-containing protein.	UBC3; Belongs to the ubiquitin-conjugating enzyme family.	0.934
GL50803_10261	GL50803_27055	A8B6W7	A8BUX6	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2-17 kDa 3.	0.510
GL50803_10261	GL50803_2876	A8B6W7	A8BVI1	SP-RING-type domain-containing protein.	UBC2, putative; Belongs to the ubiquitin-conjugating enzyme family.	0.541
GL50803_10261	GL50803_3171	A8B6W7	A8B8G9	SP-RING-type domain-containing protein.	UBCE14; Belongs to the ubiquitin-conjugating enzyme family.	0.510
GL50803_10261	GL50803_3978	A8B6W7	A8B939	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.603
GL50803_10261	GL50803_5921	A8B6W7	A8B716	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2-28.4 kDa.	0.510
GL50803_10261	GL50803_6288	A8B6W7	A8BDV8	SP-RING-type domain-containing protein.	Ubiquitin-activating enzyme E1 1.	0.476
GL50803_10261	GL50803_6524	A8B6W7	A8BE21	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2-28.4 kDa.	0.510
GL50803_10261	GL50803_7760	A8B6W7	A8BE94	SP-RING-type domain-containing protein.	Sentrin.	0.941
GL50803_10261	GL50803_8241	A8B6W7	A8B6R7	SP-RING-type domain-containing protein.	HRT1-like protein.	0.561
GL50803_10261	GL50803_8638	A8B6W7	A8BQK4	SP-RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2-28.4 kDa.	0.510
GL50803_10261	GL50803_8843	A8B6W7	A8BNL2	SP-RING-type domain-containing protein.	Ubiquitin.	0.458
GL50803_10261	GL50803_9850	A8B6W7	A8BL62	SP-RING-type domain-containing protein.	RING-type domain-containing protein.	0.575
GL50803_10361	GL50803_11434	A8BCX5	A8BBZ5	P60 katanin.	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	0.759
GL50803_10361	GL50803_11486	A8BCX5	A8BGU7	P60 katanin.	20S proteasome alpha subunit 7.	0.447
GL50803_10361	GL50803_12885	A8BCX5	A8BU21	P60 katanin.	Uncharacterized protein.	0.401