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GL50803_103074 GL50803_103074 UPPS UPPS GL50803_10324 GL50803_10324 GL50803_11897 GL50803_11897 GL50803_11043 GL50803_11043 GL50803_17316 GL50803_17316 GL50803_4507 GL50803_4507 GL50803_17143 GL50803_17143 GL50803_5857 GL50803_5857 GL50803_14975 GL50803_14975 GL50803_17579 GL50803_17579 GL50803_13890 GL50803_13890 GL50803_17277 GL50803_17277 GL50803_6492 GL50803_6492 GL50803_14855 GL50803_14855 GL50803_9077 GL50803_9077 GL50803_16356 GL50803_16356 GL50803_113133 GL50803_113133 GL50803_90402 GL50803_90402 GL50803_17502 GL50803_17502 GL50803_135885 GL50803_135885 GL50803_17406 GL50803_17406 GL50803_7573 GL50803_7573 GL50803_16599 GL50803_16599 GL50803_4964 GL50803_4964 GL50803_3983 GL50803_3983 GL50803_8589 GL50803_8589 GL50803_16130 GL50803_16130 GL50803_7203 GL50803_7203 GL50803_16495 GL50803_16495 GL50803_3180 GL50803_3180 GL50803_15267 GL50803_15267 GL50803_16483 GL50803_16483 GL50803_115159 GL50803_115159 GL50803_12109 GL50803_12109 GL50803_9829 GL50803_9829 GL50803_16269 GL50803_16269 GL50803_90872 GL50803_90872 GL50803_7259 GL50803_7259 GL50803_4255 GL50803_4255 GL50803_16906 GL50803_16906 GL50803_17205 GL50803_17205 GL50803_92618 GL50803_92618 GL50803_92645 GL50803_92645 GL50803_93938 GL50803_93938 GL50803_16556 GL50803_16556 GL50803_8822 GL50803_8822 GL50803_14200 GL50803_14200 GL50803_16558 GL50803_16558 GL50803_23420 GL50803_23420 GL50803_113610 GL50803_113610 GL50803_7511 GL50803_7511 GL50803_28232 GL50803_28232 GL50803_17258 GL50803_17258 GL50803_14135 GL50803_14135 GL50803_6335 GL50803_6335 GL50803_11301 GL50803_11301 GL50803_7009 GL50803_7009 GL50803_678 GL50803_678 GL50803_14787 GL50803_14787 GL50803_12216 GL50803_12216 GL50803_12220 GL50803_12220 GL50803_24712 GL50803_24712 GL50803_17366 GL50803_17366 GL50803_13875 GL50803_13875 GL50803_12800 GL50803_12800 GL50803_8364 GL50803_8364 GL50803_6687 GL50803_6687 GL50803_15987 GL50803_15987 GL50803_31530 GL50803_31530 GL50803_9353 GL50803_9353 GL50803_7139 GL50803_7139 GL50803_112811 GL50803_112811 GL50803_4849 GL50803_4849 GL50803_93548 GL50803_93548 GL50803_4596 GL50803_4596 GL50803_15380 GL50803_15380 GL50803_12174 GL50803_12174 GL50803_7126 GL50803_7126 GL50803_14367 GL50803_14367 GL50803_9698 GL50803_9698 GL50803_22084 GL50803_22084 GL50803_2692 GL50803_2692 GL50803_13672 GL50803_13672 GL50803_3206 GL50803_3206 GL50803_8682 GL50803_8682 GL50803_14759 GL50803_14759 GL50803_16540 GL50803_16540 GL50803_13962 GL50803_13962 GL50803_8210 GL50803_8210 GL50803_95787 GL50803_95787 GL50803_28234 GL50803_28234 GL50803_7532 GL50803_7532 GL50803_4204 GL50803_4204 GL50803_4558 GL50803_4558 GL50803_21592 GL50803_21592 GL50803_14603 GL50803_14603 GL50803_11763 GL50803_11763 GL50803_14236 GL50803_14236 GL50803_86933 GL50803_86933 GL50803_11118 GL50803_11118 GL50803_112885 GL50803_112885 GL50803_15127 GL50803_15127 GL50803_9115 GL50803_9115 GL50803_8826 GL50803_8826 GL50803_21750 GL50803_21750 GL50803_14993 GL50803_14993 GL50803_17043 GL50803_17043 GL50803_17587 GL50803_17587 GL50803_9779 GL50803_9779
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GL50803_103074PPIP5K2_N domain-containing protein. (2183 aa)
UPPSDi-trans,poly-cis-undecaprenyl-diphosphate synthase; Cis-prenyl transferase involved in the synthesis of dolichol, a long-chain polyprenol that is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Catalyzes the sequential condensation of isopentenyl pyrophosphate (IPP) with farnesyl pyrophosphate (FPP) to produce a polyprenyl pyrophosphate which contains 11 (major) and 12 (minor) isoprene units. Belongs to the UPP synthase family. (265 aa)
GL50803_10324Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (241 aa)
GL50803_11897Phosphatidylinositol-4-phosphate 5-kinase, putative. (506 aa)
GL50803_11043Fructose-bisphosphate aldolase. (323 aa)
GL50803_17316Inorganic polyphosphate/ATP-NAD kinase, putative. (553 aa)
GL50803_4507CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (895 aa)
GL50803_17143Pyruvate kinase; Belongs to the pyruvate kinase family. (553 aa)
GL50803_5857Pantothenate kinase 4. (359 aa)
GL50803_14975Phosphatidylinositol-glycan biosynthesis, class O protein. (553 aa)
GL50803_17579Inositol-3-phosphate synthase. (549 aa)
GL50803_13890Phosphatidyl synthase. (340 aa)
GL50803_17277Phospholipase B-like; Putative phospholipase. (568 aa)
GL50803_6492GP-PDE domain-containing protein. (619 aa)
GL50803_14855Phosphoinositide-3-kinase, catalytic, alpha polypeptide; Belongs to the PI3/PI4-kinase family. (2155 aa)
GL50803_9077Inositol 5-phosphatase 4. (1107 aa)
GL50803_16356Suppressor of actin 1. (582 aa)
GL50803_113133Uncharacterized protein. (837 aa)
GL50803_90402Adenylate kinase; Belongs to the adenylate kinase family. (190 aa)
GL50803_17502GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (654 aa)
GL50803_135885Uncharacterized protein. (211 aa)
GL50803_17406Phosphoinositide-3-kinase, class 3; Belongs to the PI3/PI4-kinase family. (1638 aa)
GL50803_75733-hydroxy-3-methylglutaryl-coenzyme A reductase. (751 aa)
GL50803_16599Uncharacterized protein. (2190 aa)
GL50803_4964Mevalonate kinase. (341 aa)
GL50803_39835' nucleotidase family protein. (599 aa)
GL50803_8589Suppressor of actin 1. (702 aa)
GL50803_16130TPR_REGION domain-containing protein. (440 aa)
GL50803_7203Guanylate kinase. (205 aa)
GL50803_16495Phosphatidylserine decarboxylase proenzyme. (414 aa)
GL50803_3180Dolichol-phosphate mannosyltransferase, putative. (253 aa)
GL50803_15267GPI-anchor transamidase, putative. (250 aa)
GL50803_16483Dephospho-CoA kinase. (287 aa)
GL50803_115159Phospholipase B-like; Putative phospholipase. (644 aa)
GL50803_12109PlsC domain-containing protein. (402 aa)
GL50803_9829CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (209 aa)
GL50803_16269FAD synthetase. (621 aa)
GL50803_90872Phosphoglycerate kinase. (409 aa)
GL50803_7259CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (297 aa)
GL50803_4255ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (346 aa)
GL50803_16906Phosphatidate cytidylyltransferase. (376 aa)
GL50803_172055' nucleotidase family protein. (634 aa)
GL50803_92618Nicotinamide-nucleotide adenylyltransferase. (249 aa)
GL50803_926455' nucleotidase family protein. (601 aa)
GL50803_93938Triosephosphate isomerase. (257 aa)
GL50803_16556Uncharacterized protein. (1272 aa)
GL50803_88222,3-bisphosphoglycerate-independent phosphoglycerate mutase. (589 aa)
GL50803_14200Molybdenum cofactor sulfurase. (619 aa)
GL50803_16558Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family. (2259 aa)
GL50803_23420Diphosphomevalonate decarboxylase. (335 aa)
GL50803_113610GlcNAc-PI synthesis protein. (454 aa)
GL50803_7511Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (194 aa)
GL50803_28232Uncharacterized protein. (122 aa)
GL50803_17258Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily. (216 aa)
GL50803_14135Nucleoside diphosphate kinase; Belongs to the NDK family. (387 aa)
GL50803_6335Isopentenyl-diphosphate delta-isomerase 1. (236 aa)
GL50803_11301Nucleoside diphosphate kinase; Belongs to the NDK family. (151 aa)
GL50803_7009Adenylate kinase. (253 aa)
GL50803_6785-3 deoxyribonucleotidase, putative. (216 aa)
GL50803_14787Type II inositol-1,4,5-trisphosphate 5-phosphatase. (711 aa)
GL50803_12216Vacuolar ATP synthase subunit B. (497 aa)
GL50803_12220Hydrolase, putative. (228 aa)
GL50803_24712Phosphatidylinositol-4-phosphate 5-kinase, putative. (1776 aa)
GL50803_17366NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity); Belongs to the NnrE/AIBP family. (273 aa)
GL50803_13875Phosphatase. (1025 aa)
GL50803_12800Uncharacterized protein. (383 aa)
GL50803_8364Thymidine kinase; Belongs to the thymidine kinase family. (392 aa)
GL50803_6687Glyceraldehyde-3-phosphate dehydrogenase. (336 aa)
GL50803_15987PlsC domain-containing protein. (338 aa)
GL50803_31530NH3-dependent NAD+ synthetase. (287 aa)
GL50803_9353Uncharacterized protein. (445 aa)
GL50803_7139CTP_transf_like domain-containing protein. (262 aa)
GL50803_112811Myotubularin phosphatase domain-containing protein. (705 aa)
GL50803_4849Adenylate kinase; Belongs to the adenylate kinase family. (193 aa)
GL50803_93548Phospholipase B-like; Putative phospholipase. (544 aa)
GL50803_4596Ethanolamine kinase, putative. (342 aa)
GL50803_15380CDC8. (254 aa)
GL50803_12174GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (381 aa)
GL50803_7126PlsC domain-containing protein. (424 aa)
GL50803_14367Adenylate cyclase. (642 aa)
GL50803_9698Riboflavin kinase, FMN adenylyltransferase. (138 aa)
GL50803_22084dGTP triphosphohydrolase. (689 aa)
GL50803_2692PlsC domain-containing protein. (386 aa)
GL50803_13672Nicotinamide-nucleotide adenylyltransferase. (227 aa)
GL50803_3206Pyruvate kinase; Belongs to the pyruvate kinase family. (654 aa)
GL50803_8682Glucose-6-phosphate 1-dehydrogenase. (742 aa)
GL50803_147596-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
GL50803_16540Dynein regulatory complex. (468 aa)
GL50803_13962Hydroxymethylglutaryl-CoA synthase. (489 aa)
GL50803_8210Phosphatase. (750 aa)
GL50803_95787Uncharacterized protein. (1262 aa)
GL50803_28234Adenylate kinase; Belongs to the adenylate kinase family. (285 aa)
GL50803_7532Vacuolar ATP synthase catalytic subunit A. (655 aa)
GL50803_4204MutT/nudix family protein. (247 aa)
GL50803_4558Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative. (215 aa)
GL50803_21592HD domain-containing protein. (210 aa)
GL50803_14603Nudix hydrolase domain-containing protein. (332 aa)
GL50803_11763TPK_catalytic domain-containing protein. (305 aa)
GL50803_14236Uncharacterized protein. (189 aa)
GL50803_86933Uncharacterized protein. (362 aa)
GL50803_11118Enolase. (445 aa)
GL50803_112885Adenine phosphoribosyltransferase. (180 aa)
GL50803_15127Deoxyribose-phosphate aldolase lateral transfer candidate. (258 aa)
GL50803_9115Glucose-6-phosphate isomerase; Belongs to the GPI family. (584 aa)
GL50803_8826Glucokinase. (343 aa)
GL50803_21750Ribose-phosphate pyrophosphokinase. (370 aa)
GL50803_14993Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK [...] (544 aa)
GL50803_17043Glyceraldehyde-3-phosphate dehydrogenase. (407 aa)
GL50803_17587CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (620 aa)
GL50803_9779UPL-1. (310 aa)
Your Current Organism:
Giardia lamblia ATCC 50803
NCBI taxonomy Id: 184922
Other names: G. lamblia ATCC 50803, Giardia intestinalis ATCC 50803
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