(5 nodes) tRNA thio-modification network (Giardia lamblia ATCC 50803)

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Your Input:
	GL50803_115232	ATP_bind_3 domain-containing protein. (552 aa)
	GL50803_7368	ATPases of the PP-loop superfamily. (301 aa)
	GL50803_11449	ATPase of the PP-loop superfamily implicated in cell cycle control, putative. (351 aa)
	GL50803_11884	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...] (95 aa)
	GL50803_12853	Molybdopterin biosynthesis MoeB protein. (274 aa)

Your Current Organism:

Giardia lamblia ATCC 50803

NCBI taxonomy Id: 184922
Other names: G. lamblia ATCC 50803, Giardia intestinalis ATCC 50803

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GL50803_11449	GL50803_11884	A8BC16	A8B2R1	ATPase of the PP-loop superfamily implicated in cell cycle control, putative.	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	0.568
GL50803_11449	GL50803_12853	A8BC16	A8BU12	ATPase of the PP-loop superfamily implicated in cell cycle control, putative.	Molybdopterin biosynthesis MoeB protein.	0.576
GL50803_115232	GL50803_11884	A8BA86	A8B2R1	ATP_bind_3 domain-containing protein.	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	0.568
GL50803_115232	GL50803_12853	A8BA86	A8BU12	ATP_bind_3 domain-containing protein.	Molybdopterin biosynthesis MoeB protein.	0.576
GL50803_11884	GL50803_11449	A8B2R1	A8BC16	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	ATPase of the PP-loop superfamily implicated in cell cycle control, putative.	0.568
GL50803_11884	GL50803_115232	A8B2R1	A8BA86	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	ATP_bind_3 domain-containing protein.	0.568
GL50803_11884	GL50803_12853	A8B2R1	A8BU12	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	Molybdopterin biosynthesis MoeB protein.	0.999
GL50803_11884	GL50803_7368	A8B2R1	A8BC83	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	ATPases of the PP-loop superfamily.	0.568
GL50803_12853	GL50803_11449	A8BU12	A8BC16	Molybdopterin biosynthesis MoeB protein.	ATPase of the PP-loop superfamily implicated in cell cycle control, putative.	0.576
GL50803_12853	GL50803_115232	A8BU12	A8BA86	Molybdopterin biosynthesis MoeB protein.	ATP_bind_3 domain-containing protein.	0.576
GL50803_12853	GL50803_11884	A8BU12	A8B2R1	Molybdopterin biosynthesis MoeB protein.	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	0.999
GL50803_12853	GL50803_7368	A8BU12	A8BC83	Molybdopterin biosynthesis MoeB protein.	ATPases of the PP-loop superfamily.	0.576
GL50803_7368	GL50803_11884	A8BC83	A8B2R1	ATPases of the PP-loop superfamily.	Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]	0.568
GL50803_7368	GL50803_12853	A8BC83	A8BU12	ATPases of the PP-loop superfamily.	Molybdopterin biosynthesis MoeB protein.	0.576