(91 nodes) Nucleobase-containing compound biosynthetic process network (Giardia lamblia ATCC 50803)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GL50803_24133	5'-3' exoribonuclease 2. (902 aa)
	GL50803_121061	RNA polymerase III subunit C34. (233 aa)
	GL50803_16810	DINP protein, human muc B family. (675 aa)
	GL50803_16483	Dephospho-CoA kinase. (287 aa)
	GL50803_137619	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
	GL50803_16269	FAD synthetase. (621 aa)
	GL50803_11384	DNA helicase. (899 aa)
	GL50803_115694	SprT-like domain-containing protein. (227 aa)
	GL50803_5158	Transcription factor TFIIS. (346 aa)
	GL50803_92618	Nicotinamide-nucleotide adenylyltransferase. (249 aa)
	GL50803_6564	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (299 aa)
	GL50803_10775	Uncharacterized protein. (450 aa)
	GL50803_28232	Uncharacterized protein. (122 aa)
	GL50803_17258	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily. (216 aa)
	GL50803_14135	Nucleoside diphosphate kinase; Belongs to the NDK family. (387 aa)
	GL50803_11301	Nucleoside diphosphate kinase; Belongs to the NDK family. (151 aa)
	GL50803_16512	DNA repair helicase TFIIH P90. (765 aa)
	GL50803_4155	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (487 aa)
	GL50803_16370	Transcriptional activator, putative. (1859 aa)
	GL50803_7009	Adenylate kinase. (253 aa)
	GL50803_12220	Hydrolase, putative. (228 aa)
	GL50803_113365	5'-3' exoribonuclease 2. (1956 aa)
	GL50803_112207	VSP. (205 aa)
	GL50803_12800	Uncharacterized protein. (383 aa)
	GL50803_8364	Thymidine kinase; Belongs to the thymidine kinase family. (392 aa)
	GL50803_31530	NH3-dependent NAD+ synthetase. (287 aa)
	GL50803_7139	CTP_transf_like domain-containing protein. (262 aa)
	GL50803_4849	Adenylate kinase; Belongs to the adenylate kinase family. (193 aa)
	GL50803_15380	CDC8. (254 aa)
	GL50803_14367	Adenylate cyclase. (642 aa)
	GL50803_9698	Riboflavin kinase, FMN adenylyltransferase. (138 aa)
	GL50803_13672	Nicotinamide-nucleotide adenylyltransferase. (227 aa)
	GL50803_27326	DNA polymerase. (1730 aa)
	GL50803_137740	VSP. (451 aa)
	GL50803_17187	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1238 aa)
	GL50803_101501	Seryl-tRNA synthetase. (457 aa)
	GL50803_17316	Inorganic polyphosphate/ATP-NAD kinase, putative. (553 aa)
	GL50803_4507	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (895 aa)
	GL50803_5857	Pantothenate kinase 4. (359 aa)
	GL50803_16225	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (960 aa)
	GL50803_16223	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1741 aa)
	GL50803_6918	DNA damage repair protein. (867 aa)
	GL50803_6980	DNA pol/primase, large sub. (539 aa)
	GL50803_14651	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (148 aa)
	GL50803_8423	Enkurin domain-containing protein. (293 aa)
	GL50803_90402	Adenylate kinase; Belongs to the adenylate kinase family. (190 aa)
	GL50803_10840	DNA-directed RNA polymerases I and III 16 kDa polypeptide. (101 aa)
	GL50803_23496	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (2142 aa)
	GL50803_29436	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1235 aa)
	GL50803_11742	Transcription factor RRN3. (556 aa)
	GL50803_3974	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide. (215 aa)
	GL50803_16599	Uncharacterized protein. (2190 aa)
	GL50803_10055	DNA-directed RNA polymerase subunit D. (350 aa)
	GL50803_14413	DNA-directed RNA polymerase RPB10. (122 aa)
	GL50803_7649	DNA ligase. (810 aa)
	GL50803_14083	Uncharacterized protein. (512 aa)
	GL50803_16540	Dynein regulatory complex. (468 aa)
	GL50803_114670	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (449 aa)
	GL50803_95787	Uncharacterized protein. (1262 aa)
	GL50803_4328	TFIIH basal transcription factor complex helicase subunit. (840 aa)
	GL50803_28234	Adenylate kinase; Belongs to the adenylate kinase family. (285 aa)
	GL50803_4558	Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative. (215 aa)
	GL50803_100969	Uncharacterized protein. (175 aa)
	GL50803_99228	Uncharacterized protein. (80 aa)
	GL50803_99389	Uncharacterized protein. (80 aa)
	GL50803_15955	DNA-directed RNA polymerase II RPB6. (104 aa)
	GL50803_17495	RAD50 DNA repair protein, putative. (1387 aa)
	GL50803_16217	UDP-N-acetylglucosamine pyrophosphorylase. (436 aa)
	GL50803_4125	Transcription factor IIIB 70 kDa subunit BRF. (476 aa)
	GL50803_102515	RNA-directed RNA polymerase, putative. (2001 aa)
	GL50803_112885	Adenine phosphoribosyltransferase. (180 aa)
	GL50803_3036	RNA polymerase II subunit Rpb11. (131 aa)
	GL50803_14259	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (205 aa)
	GL50803_7474	DNA-directed RNA polymerase RPB3. (326 aa)
	GL50803_17448	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1293 aa)
	GL50803_15144	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	GL50803_21750	Ribose-phosphate pyrophosphokinase. (370 aa)
	GL50803_91348	Purine nucleoside phosphorylase lateral transfer candidate. (805 aa)
	GL50803_137609	RNA polymerase II subunit Rpb5a. (229 aa)
	GL50803_1721	TATA-binding protein-like factor. (200 aa)
	GL50803_8157	RNA polymerase II subunit Rpb5b. (201 aa)
	GL50803_17587	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (620 aa)
	GL50803_15000	TFIIH P44. (406 aa)
	GL50803_8595	VSP. (127 aa)
	GL50803_8518	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (103 aa)
	GL50803_16130	TPR_REGION domain-containing protein. (440 aa)
	GL50803_112693	VSP. (258 aa)
	GL50803_7203	Guanylate kinase. (205 aa)
	GL50803_35094	DNA polymerase. (1329 aa)
	GL50803_17430	DRE4 protein. (1165 aa)
	GL50803_23064	DNA polymerase epsilon, catalytic subunit. (2590 aa)

Your Current Organism:

Giardia lamblia ATCC 50803

NCBI taxonomy Id: 184922
Other names: G. lamblia ATCC 50803, Giardia intestinalis ATCC 50803

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GL50803_10055	GL50803_101501	A8B9C8	A8B2X0	DNA-directed RNA polymerase subunit D.	Seryl-tRNA synthetase.	0.632
GL50803_10055	GL50803_10840	A8B9C8	A8B7A8	DNA-directed RNA polymerase subunit D.	DNA-directed RNA polymerases I and III 16 kDa polypeptide.	0.999
GL50803_10055	GL50803_11301	A8B9C8	A8BMG9	DNA-directed RNA polymerase subunit D.	Nucleoside diphosphate kinase; Belongs to the NDK family.	0.590
GL50803_10055	GL50803_11742	A8B9C8	A8B8V3	DNA-directed RNA polymerase subunit D.	Transcription factor RRN3.	0.999
GL50803_10055	GL50803_121061	A8B9C8	A8BDP8	DNA-directed RNA polymerase subunit D.	RNA polymerase III subunit C34.	0.999
GL50803_10055	GL50803_12220	A8B9C8	A8BPW1	DNA-directed RNA polymerase subunit D.	Hydrolase, putative.	0.483
GL50803_10055	GL50803_137609	A8B9C8	E2RU58	DNA-directed RNA polymerase subunit D.	RNA polymerase II subunit Rpb5a.	0.987
GL50803_10055	GL50803_137619	A8B9C8	A8BG20	DNA-directed RNA polymerase subunit D.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.999
GL50803_10055	GL50803_14083	A8B9C8	A8BX96	DNA-directed RNA polymerase subunit D.	Uncharacterized protein.	0.999
GL50803_10055	GL50803_14135	A8B9C8	A8BLA6	DNA-directed RNA polymerase subunit D.	Nucleoside diphosphate kinase; Belongs to the NDK family.	0.590
GL50803_10055	GL50803_14413	A8B9C8	A8BAL6	DNA-directed RNA polymerase subunit D.	DNA-directed RNA polymerase RPB10.	0.999
GL50803_10055	GL50803_15000	A8B9C8	A8BAS0	DNA-directed RNA polymerase subunit D.	TFIIH P44.	0.906
GL50803_10055	GL50803_15144	A8B9C8	E2RU32	DNA-directed RNA polymerase subunit D.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
GL50803_10055	GL50803_15955	A8B9C8	E2RTN0	DNA-directed RNA polymerase subunit D.	DNA-directed RNA polymerase II RPB6.	0.999
GL50803_10055	GL50803_16130	A8B9C8	A8BBK4	DNA-directed RNA polymerase subunit D.	TPR_REGION domain-containing protein.	0.554
GL50803_10055	GL50803_16223	A8B9C8	A8B4F1	DNA-directed RNA polymerase subunit D.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
GL50803_10055	GL50803_16370	A8B9C8	A8BMN2	DNA-directed RNA polymerase subunit D.	Transcriptional activator, putative.	0.612
GL50803_10055	GL50803_16512	A8B9C8	A8BMI7	DNA-directed RNA polymerase subunit D.	DNA repair helicase TFIIH P90.	0.907
GL50803_10055	GL50803_17187	A8B9C8	A8B2N4	DNA-directed RNA polymerase subunit D.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
GL50803_10055	GL50803_1721	A8B9C8	E2RU70	DNA-directed RNA polymerase subunit D.	TATA-binding protein-like factor.	0.938