(52 nodes) Protein-containing complex assembly network (Giardia lamblia ATCC 50803)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GL50803_9352	U5 small nuclear ribonucleoprotein 200 kDa helicase, putative. (1594 aa)
	GL50803_112114	Splicing factor-like protein, putative. (2309 aa)
	GL50803_17565	RuvB-like helicase; Belongs to the RuvB family. (483 aa)
	GL50803_135001	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (99 aa)
	GL50803_96399	Spindle pole body protein, putative. (1670 aa)
	GL50803_91398	Eukaryotic translation initiation factor 2 beta subunit. (330 aa)
	GL50803_12981	Ribosomal protein S5. (190 aa)
	GL50803_137724	Uncharacterized protein. (380 aa)
	GL50803_11190	Uncharacterized protein. (538 aa)
	GL50803_5522	Uncharacterized protein. (1007 aa)
	GL50803_13346	Dmc1b; Belongs to the RecA family. (368 aa)
	GL50803_4125	Transcription factor IIIB 70 kDa subunit BRF. (476 aa)
	GL50803_13104	DNA repair protein RAD51; Belongs to the RecA family. (389 aa)
	GL50803_17395	Ribosomal protein L5. (297 aa)
	GL50803_13412	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (251 aa)
	GL50803_13988	Uncharacterized protein. (1010 aa)
	GL50803_15538	Eukaryotic translation initiation factor 5. (337 aa)
	GL50803_112870	Uncharacterized protein. (121 aa)
	GL50803_2523	DUF4200 domain-containing protein. (754 aa)
	GL50803_16535	Tubulin specific chaperone E. (618 aa)
	GL50803_15495	RRM domain-containing protein. (871 aa)
	GL50803_137731	Uncharacterized protein. (1043 aa)
	GL50803_15260	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
	GL50803_33433	Uncharacterized protein. (233 aa)
	GL50803_5462	Delta tubulin; Belongs to the tubulin family. (446 aa)
	GL50803_7030	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (192 aa)
	GL50803_17429	Spindle pole body component. (985 aa)
	GL50803_6835	Brix domain containing protein. (332 aa)
	GL50803_10145	Tubulin specific chaperone D. (1291 aa)
	GL50803_13897	MCT-1 protein-like protein. (237 aa)
	GL50803_7766	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (245 aa)
	GL50803_4954	Small nuclear ribonucleoprotein F, putative. (107 aa)
	GL50803_101278	Uncharacterized protein. (1330 aa)
	GL50803_9184	Transducin. (776 aa)
	GL50803_9825	RuvB-like helicase; Belongs to the RuvB family. (468 aa)
	GL50803_121045	Histone H2B; Belongs to the histone H2B family. (130 aa)
	GL50803_10755	Splicing factor 3A subunit 2. (222 aa)
	GL50803_3589	Ribosome biogenesis protein Brix. (348 aa)
	GL50803_17335	Kinase, CMGC SRPK. (902 aa)
	GL50803_32297	Small nuclear ribonucleoprotein Sm D2, putative. (124 aa)
	GL50803_10429	Wos2 protein. (185 aa)
	GL50803_10428	Ribosomal protein L10. (210 aa)
	GL50803_7870	Ribosomal protein L23A; Belongs to the universal ribosomal protein uL23 family. (141 aa)
	GL50803_91476	Uncharacterized protein. (1068 aa)
	GL50803_91480	STU2-like protein. (1712 aa)
	GL50803_17054	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (326 aa)
	GL50803_114218	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (491 aa)
	GL50803_17030	Chaperone protein dnaJ. (224 aa)
	GL50803_16237	Uncharacterized protein. (678 aa)
	GL50803_14119	Zinc finger domain protein. (268 aa)
	GL50803_13661	Eukaryotic translation initiation factor 3 subunit 2. (350 aa)
	GL50803_16263	Sjogren's syndrome nuclear autoantigen 1-like protein. (106 aa)

Your Current Organism:

Giardia lamblia ATCC 50803

NCBI taxonomy Id: 184922
Other names: G. lamblia ATCC 50803, Giardia intestinalis ATCC 50803

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GL50803_10145	GL50803_16535	A8BDA2	A8B5R2	Tubulin specific chaperone D.	Tubulin specific chaperone E.	0.618
GL50803_10428	GL50803_12981	A8BM86	A8BZD3	Ribosomal protein L10.	Ribosomal protein S5.	0.999
GL50803_10428	GL50803_13412	A8BM86	A8BN05	Ribosomal protein L10.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.946
GL50803_10428	GL50803_13661	A8BM86	A8BRM0	Ribosomal protein L10.	Eukaryotic translation initiation factor 3 subunit 2.	0.482
GL50803_10428	GL50803_15260	A8BM86	A8BBP3	Ribosomal protein L10.	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.999
GL50803_10428	GL50803_17054	A8BM86	A8BNT0	Ribosomal protein L10.	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.	0.999
GL50803_10428	GL50803_17395	A8BM86	E2RU47	Ribosomal protein L10.	Ribosomal protein L5.	0.999
GL50803_10428	GL50803_7766	A8BM86	A8BE86	Ribosomal protein L10.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.999
GL50803_10428	GL50803_7870	A8BM86	A8BMP6	Ribosomal protein L10.	Ribosomal protein L23A; Belongs to the universal ribosomal protein uL23 family.	0.999
GL50803_10755	GL50803_11190	A8BJH8	D3KGI0	Splicing factor 3A subunit 2.	Uncharacterized protein.	0.778
GL50803_10755	GL50803_112114	A8BJH8	A8BTS5	Splicing factor 3A subunit 2.	Splicing factor-like protein, putative.	0.999
GL50803_10755	GL50803_32297	A8BJH8	A8BLX8	Splicing factor 3A subunit 2.	Small nuclear ribonucleoprotein Sm D2, putative.	0.999
GL50803_10755	GL50803_4954	A8BJH8	A8BEC2	Splicing factor 3A subunit 2.	Small nuclear ribonucleoprotein F, putative.	0.999
GL50803_10755	GL50803_5522	A8BJH8	D3KHM3	Splicing factor 3A subunit 2.	Uncharacterized protein.	0.999
GL50803_10755	GL50803_91476	A8BJH8	A8BNR9	Splicing factor 3A subunit 2.	Uncharacterized protein.	0.999
GL50803_10755	GL50803_9352	A8BJH8	A8BT20	Splicing factor 3A subunit 2.	U5 small nuclear ribonucleoprotein 200 kDa helicase, putative.	0.999
GL50803_11190	GL50803_10755	D3KGI0	A8BJH8	Uncharacterized protein.	Splicing factor 3A subunit 2.	0.778
GL50803_11190	GL50803_112114	D3KGI0	A8BTS5	Uncharacterized protein.	Splicing factor-like protein, putative.	0.449
GL50803_11190	GL50803_32297	D3KGI0	A8BLX8	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2, putative.	0.550
GL50803_11190	GL50803_4954	D3KGI0	A8BEC2	Uncharacterized protein.	Small nuclear ribonucleoprotein F, putative.	0.879