(13 nodes) Ribonuclease H superfamily network (Giardia lamblia ATCC 50803)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GL50803_9430	Uncharacterized protein. (665 aa)
	GL50803_23064	DNA polymerase epsilon, catalytic subunit. (2590 aa)
	Ago	Protein argonaute; Plays an essential role in growth and, with Dicer, also involved in microRNA (miRNA)-mediated translational repression. The RNA interference pathway is implicated in antigenic variation having a role in regulation of variant-specific surface protein (VSP)-coding gene expression. Several VSP genes are transcribed but only transcripts encoding the VSP to be expressed accumulate. Antisense RNAs corresponding to the silenced VSP genes are detected (By similarity). Belongs to the argonaute family. Ago subfamily. (900 aa)
	GL50803_93851	DNA polymerase, putative. (980 aa)
	GL50803_5823	Uncharacterized protein. (262 aa)
	GL50803_10606	CCR4-NOT transcription complex, subunit 7. (260 aa)
	GL50803_27326	DNA polymerase. (1730 aa)
	GL50803_8209	CCR4-NOT transcription complex, subunit 7. (265 aa)
	GL50803_137688	DNA polymerase, putative. (1198 aa)
	GL50803_35094	DNA polymerase. (1329 aa)
	GL50803_14763	Exonuclease. (630 aa)
	GL50803_34134	Ribonuclease H. (352 aa)
	GL50803_6483	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (243 aa)

Your Current Organism:

Giardia lamblia ATCC 50803

NCBI taxonomy Id: 184922
Other names: G. lamblia ATCC 50803, Giardia intestinalis ATCC 50803

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GL50803_10606	GL50803_8209	A8BP49	A8BYI1	CCR4-NOT transcription complex, subunit 7.	CCR4-NOT transcription complex, subunit 7.	0.902
GL50803_14763	GL50803_34134	A8BAE3	A8B979	Exonuclease.	Ribonuclease H.	0.812
GL50803_14763	GL50803_6483	A8BAE3	A8B5I7	Exonuclease.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.552
GL50803_23064	GL50803_27326	A8BDM4	A8BW96	DNA polymerase epsilon, catalytic subunit.	DNA polymerase.	0.997
GL50803_23064	GL50803_34134	A8BDM4	A8B979	DNA polymerase epsilon, catalytic subunit.	Ribonuclease H.	0.402
GL50803_23064	GL50803_35094	A8BDM4	A8BCF5	DNA polymerase epsilon, catalytic subunit.	DNA polymerase.	0.991
GL50803_23064	GL50803_6483	A8BDM4	A8B5I7	DNA polymerase epsilon, catalytic subunit.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.883
GL50803_27326	GL50803_23064	A8BW96	A8BDM4	DNA polymerase.	DNA polymerase epsilon, catalytic subunit.	0.997
GL50803_27326	GL50803_34134	A8BW96	A8B979	DNA polymerase.	Ribonuclease H.	0.488
GL50803_27326	GL50803_35094	A8BW96	A8BCF5	DNA polymerase.	DNA polymerase.	0.977
GL50803_27326	GL50803_6483	A8BW96	A8B5I7	DNA polymerase.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.729
GL50803_34134	GL50803_14763	A8B979	A8BAE3	Ribonuclease H.	Exonuclease.	0.812
GL50803_34134	GL50803_23064	A8B979	A8BDM4	Ribonuclease H.	DNA polymerase epsilon, catalytic subunit.	0.402
GL50803_34134	GL50803_27326	A8B979	A8BW96	Ribonuclease H.	DNA polymerase.	0.488
GL50803_34134	GL50803_6483	A8B979	A8B5I7	Ribonuclease H.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.905
GL50803_35094	GL50803_23064	A8BCF5	A8BDM4	DNA polymerase.	DNA polymerase epsilon, catalytic subunit.	0.991
GL50803_35094	GL50803_27326	A8BCF5	A8BW96	DNA polymerase.	DNA polymerase.	0.977
GL50803_35094	GL50803_6483	A8BCF5	A8B5I7	DNA polymerase.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.703
GL50803_6483	GL50803_14763	A8B5I7	A8BAE3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Exonuclease.	0.552
GL50803_6483	GL50803_23064	A8B5I7	A8BDM4	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase epsilon, catalytic subunit.	0.883