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| | ANH95191.1 | Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (350 aa) |
| | ANH95193.1 | Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa) |
| | ANH90046.1 | Benzoylformate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (526 aa) |
| | ANH90047.1 | Benzaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (484 aa) |
| | ANH90048.1 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa) |
| | ANH90152.1 | Serine/threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | ANH90298.1 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa) |
| | ANH90461.1 | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (282 aa) |
| | hisE | phosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa) |
| | metK | Primosome assembly protein PriA; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa) |
| | ANH90607.1 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (275 aa) |
| | ANH90646.1 | 4-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | ANH90647.1 | Chloride transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa) |
| | ANH90747.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1178 aa) |
| | ANH90834.1 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa) |
| | ANH90835.1 | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa) |
| | ANH95286.1 | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | dapA-2 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (309 aa) |
| | dapD | Hypothetical protein; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (328 aa) |
| | aroQ | Type II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (153 aa) |
| | ANH91041.1 | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (427 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (269 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (496 aa) |
| | ANH91064.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | ANH91066.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa) |
| | priA | Phosphoribosyl isomerase A; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (242 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa) |
| | hisC | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (378 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (441 aa) |
| | ANH91072.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa) |
| | ANH91074.1 | ATP-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | ANH91075.1 | aminoacyl-tRNA deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (166 aa) |
| | ANH91119.1 | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (307 aa) |
| | ANH91129.1 | 3-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (450 aa) |
| | ANH91130.1 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (354 aa) |
| | ANH91409.1 | Adenosylhomocysteinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa) |
| | ANH91440.1 | Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (306 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (576 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa) |
| | ANH91645.1 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (561 aa) |
| | ANH91715.1 | Very short patch repair endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa) |
| | ANH91716.1 | 5-methylcytosine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (331 aa) |
| | ANH95386.1 | DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (451 aa) |
| | ahcY | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (485 aa) |
| | ANH91880.1 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa) |
| | serC | Dimethylmenaquinone methyltransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa) |
| | ANH92117.1 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa) |
| | ANH92359.1 | Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa) |
| | pat | Histidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa) |
| | ANH92387.1 | Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa) |
| | ANH92450.1 | Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa) |
| | ANH92598.1 | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa) |
| | pat-2 | Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (358 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (325 aa) |
| | ANH92637.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (429 aa) |
| | ANH92638.1 | Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa) |
| | ANH92665.1 | Inhibition of morphological differentiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa) |
| | ANH95502.1 | DNA (cytosine-5-)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa) |
| | ANH92687.1 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (617 aa) |
| | ANH92907.1 | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa) |
| | ANH93012.1 | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa) |
| | ANH93140.1 | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa) |
| | ANH93143.1 | Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa) |
| | ANH93227.1 | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | ANH93265.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa) |
| | ANH93267.1 | Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (106 aa) |
| | ANH93268.1 | Succinyldiaminopimelate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa) |
| | ANH93337.1 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa) |
| | ANH95596.1 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa) |
| | ANH93423.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (595 aa) |
| | ANH93550.1 | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa) |
| | ANH95609.1 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa) |
| | ANH93569.1 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (617 aa) |
| | ANH93570.1 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa) |
| | ANH93572.1 | Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (347 aa) |
| | ANH93580.1 | Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa) |
| | ANH93591.1 | Citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (534 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (476 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa) |
| | dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (250 aa) |
| | dapA-3 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (289 aa) |
| | A8713_24025 | Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (457 aa) |
| | ANH95636.1 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa) |
| | ANH94118.1 | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa) |
| | A8713_28220 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa) |
| | ANH94690.1 | Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (560 aa) |
| | ANH95129.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (310 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (444 aa) |
