(88 nodes) Quorum sensing network (Streptomyces sp. SAT1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANH89719.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1052 aa)
	ANH89720.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (435 aa)
	ANH89812.1	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
	ANH89813.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
	ANH89814.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
	ANH89815.1	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
	ANH89837.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
	ANH89838.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
	ANH95188.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
	ANH89902.1	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (694 aa)
	ANH95189.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
	ANH89903.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
	ANH90623.1	Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
	ANH90745.1	Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
	ANH90777.1	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
	ANH90978.1	Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (76 aa)
	ANH95293.1	Branched chain amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
	ANH91029.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (310 aa)
	ANH95294.1	Branched-chain amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (590 aa)
	ANH91030.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
	ANH91031.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
	trpE	Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (496 aa)
	ANH91129.1	3-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (450 aa)
	ANH91130.1	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
	ANH91140.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
	ANH91397.1	Peptidase; Extracellular zinc metalloprotease. (548 aa)
	ANH91467.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
	ANH95383.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
	secA	Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (938 aa)
	ANH92425.1	Membrane protein insertase YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	ANH92443.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (507 aa)
	secF-2	Protein translocase subunit SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (779 aa)
	ANH92655.1	Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	secE	Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (94 aa)
	secY	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
	ANH93065.1	Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
	ANH93238.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
	ANH93240.1	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
	ANH93241.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
	ANH93242.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
	ANH93243.1	Methionine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (352 aa)
	ANH93244.1	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (382 aa)
	ANH93245.1	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
	ANH93246.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	ANH93247.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
	ANH95567.1	Methionine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (324 aa)
	ANH93248.1	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (341 aa)
	ANH93299.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
	ANH93300.1	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
	ANH93301.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
	ANH95574.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (602 aa)
	ANH93499.1	Peptidase; Extracellular zinc metalloprotease. (546 aa)
	ANH93531.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
	ANH93532.1	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
	ANH93533.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
	ANH93534.1	Dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (365 aa)
	ftsY	Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (404 aa)
	ffh	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (515 aa)
	ANH93747.1	Dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (339 aa)
	ANH93748.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
	ANH95623.1	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
	ANH93749.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
	A8713_24025	Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (457 aa)
	ANH95636.1	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
	ANH95637.1	Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
	ANH93923.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	ANH94129.1	Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
	ANH94279.1	Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (476 aa)
	ANH94326.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa)
	ANH94349.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
	ANH94370.1	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (345 aa)
	ANH94371.1	Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
	ANH94372.1	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
	ANH95697.1	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
	ANH94386.1	Phospholipase C, phosphocholine-specific; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)
	ANH94490.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (223 aa)
	ANH94516.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
	ANH94697.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (690 aa)
	ANH94698.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
	ANH94699.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
	ANH95735.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
	ANH94840.1	Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
	ANH94873.1	Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
	ANH94927.1	Phospholipase C, phosphocholine-specific; Derived by automated computational analysis using gene prediction method: Protein Homology. (674 aa)
	ANH95782.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
	ANH94970.1	Subtilin biosynthesis protein spaC; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
	ANH95112.1	Flagellar biosynthesis protein FlgM; Extracellular zinc metalloprotease. (591 aa)
	ANH95799.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)

Your Current Organism:

Streptomyces sp. SAT1

NCBI taxonomy Id: 1849967
Other names: S. sp. SAT1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A8713_24025	ANH91129.1	A8713_24025	A8713_08000	Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family.	3-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family.	0.902
A8713_24025	ANH91130.1	A8713_24025	A8713_08010	Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family.	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.493
A8713_24025	ANH95636.1	A8713_24025	A8713_24030	Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family.	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.880
A8713_24025	ANH95637.1	A8713_24025	A8713_24035	Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family.	Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.743
ANH89719.1	ANH89720.1	A8713_00050	A8713_00055	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.983
ANH89719.1	ANH94970.1	A8713_00050	A8713_30520	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Subtilin biosynthesis protein spaC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.782
ANH89720.1	ANH89719.1	A8713_00055	A8713_00050	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.983
ANH89720.1	ANH94970.1	A8713_00055	A8713_30520	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Subtilin biosynthesis protein spaC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929
ANH89812.1	ANH89813.1	A8713_00600	A8713_00605	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
ANH89812.1	ANH89814.1	A8713_00600	A8713_00610	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
ANH89812.1	ANH89815.1	A8713_00600	A8713_00615	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.943
ANH89812.1	ANH89837.1	A8713_00600	A8713_00735	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.704
ANH89812.1	ANH89838.1	A8713_00600	A8713_00740	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.512
ANH89812.1	ANH89902.1	A8713_00600	A8713_01095	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.406
ANH89812.1	ANH89903.1	A8713_00600	A8713_01105	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.529
ANH89812.1	ANH90745.1	A8713_00600	A8713_05885	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.465
ANH89812.1	ANH93065.1	A8713_00600	A8713_19425	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.511
ANH89812.1	ANH93240.1	A8713_00600	A8713_20475	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.675
ANH89812.1	ANH93241.1	A8713_00600	A8713_20480	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.701
ANH89812.1	ANH93242.1	A8713_00600	A8713_20485	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664