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| | bhn_I0848 | CDP-diglyceride synthetase. (274 aa) |
| | pyrH | UMP kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (231 aa) |
| | bhn_I0836 | Competence/damage-inducible protein CinA C-terminal domain-containing protein. (162 aa) |
| | bhn_I0808 | Phosphoribulokinase/uridine kinase family protein. (551 aa) |
| | bhn_I1441 | Flagellar protein export ATPase FliI, fliI. (452 aa) |
| | purD | Phosphoribosylamine--glycine ligase PurD; Belongs to the GARS family. (427 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (214 aa) |
| | bhn_I2290 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD. (528 aa) |
| | bhn_I2338 | Cytidylate kinase. (212 aa) |
| | bhn_I2366 | NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (250 aa) |
| | pncB | Nicotinate phosphoribosyltransferase PncB; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (401 aa) |
| | bhn_I2406 | ATP-grasp domain-containing protein. (331 aa) |
| | bhn_I2425 | ATP-grasp domain-containing protein. (400 aa) |
| | bhn_I2428 | Hypothetical protein. (407 aa) |
| | dacA | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (288 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (400 aa) |
| | bhn_I2514 | Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (404 aa) |
| | upp | Uracil phosphoribosyltransferase Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | bhn_I2550 | RNA-binding protein. (302 aa) |
| | bhn_I2572 | FRG domain-containing protein. (267 aa) |
| | bhn_I2597 | Adenosine deaminase Add. (315 aa) |
| | guaA | GMP synthase GuaA; Catalyzes the synthesis of GMP from XMP. (516 aa) |
| | bhn_I2608 | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase IspE. (289 aa) |
| | pyrD | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate. (301 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (266 aa) |
| | bhn_I2612 | Dihydroorotase PyrC. (429 aa) |
| | bhn_I2613 | 1-acylglycerol-3-phosphate O-acyltransferase. (247 aa) |
| | bhn_I2704 | Hypoxanthine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (174 aa) |
| | AOZ94969.1 | Phosphoribosyltransferase domain-containing protein. (212 aa) |
| | AOZ94991.1 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ. (146 aa) |
| | AOZ94992.1 | acetyl-CoA carboxylase biotin carboxylase AccC. (449 aa) |
| | accD | acetyl-CoA carboxylase carboxyl transferase beta subunit AccD; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (276 aa) |
| | AOZ94994.1 | acetyl-CoA carboxylase carboxyl transferase alpha subunit AccA. (251 aa) |
| | bhn_I1456 | RelA/SpoT domain-containing protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (759 aa) |
| | apt | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (174 aa) |
| | bhn_I1491 | NAD-binding oxidoreductase. (291 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | bhn_I1506 | Thiamine pyrophosphokinase. (223 aa) |
| | bhn_I1513 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (180 aa) |
| | gmk | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | bhn_I1523 | dephospho-CoA kinase CoaE. (206 aa) |
| | atpC-2 | ATP synthase F1 epsilon subunit AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane. (141 aa) |
| | atpD-2 | ATP synthase F1 beta subunit AtpD; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (463 aa) |
| | atpG-2 | ATP synthase F1 gamma subunit AtpG; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (310 aa) |
| | atpA-2 | ATP synthase F1 alpha subunit AtpA; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (597 aa) |
| | bhn_I1572 | ATP synthase F0 B subunit AtpF. (163 aa) |
| | atpE-2 | ATP synthase F0 C subunit AtpE; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (72 aa) |
| | bhn_I1574 | ATP synthase F0 A subunit AtpB. (229 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. (290 aa) |
| | pyrB | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (318 aa) |
| | bhn_I1627 | Aspartate carbamoyltransferase regulatory subunit PyrI. (147 aa) |
| | bhn_I1642 | Lipid kinase YegS/Rv2252/BmrU family. (323 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (181 aa) |
| | bhn_I1727 | Xanthine phosphoribosyltransferase Xpt. (192 aa) |
| | bhn_I1769 | DNA topology modulation protein FlaR. (171 aa) |
| | bhn_I1826 | HD family phosphohydrolase. (198 aa) |
| | bhn_I1837 | Ribosomal protein S1 RpsA. (380 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (284 aa) |
| | cmk | Cytidylate kinase. (219 aa) |
| | carB | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. (1088 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit CarA; Belongs to the CarA family. (403 aa) |
| | bhn_I1937 | Phosphoribosylformylglycinamidine synthase PurL. (1268 aa) |
| | purA | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa) |
| | bhn_I1988 | Radical SAM domain-containing protein. (311 aa) |
| | adk | Adenylate kinases Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | bhn_I2085 | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (504 aa) |
| | purF | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (481 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (434 aa) |
| | bhn_I2115 | Thiamine-phosphate pyrophosphorylase ThiE. (211 aa) |
| | bhn_I2116 | Hydroxyethylthiazole kinase ThiM. (272 aa) |
| | bhn_I2128 | Lipid kinase YegS/Rv2252/BmrU family. (300 aa) |
| | thyA | Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (283 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (483 aa) |
| | bhn_I2250 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (398 aa) |
| | bhn_I2251 | Pantothenate kinase CoaX. (260 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase PurM. (343 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (166 aa) |
| | pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (226 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. (308 aa) |
| | bhn_I0733 | Response regulator domain-containing protein. (256 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | bhn_I1345 | Nicotinate nucleotide adenylyltransferase NadD. (202 aa) |
| | bhn_I1344 | HD family phosphohydrolase. (194 aa) |
| | bhn_I1336 | Cytidylate kinase. (211 aa) |
| | bhn_I1311 | dUTP diphosphatase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (145 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (340 aa) |
| | bhn_I1282 | Acyl-phosphate glycerol 3-phosphate acyltransferase PlsY. (233 aa) |
| | bhn_I1279 | Phosphoribosylpyrophosphate synthetase Prs; Belongs to the ribose-phosphate pyrophosphokinase family. (399 aa) |
| | bhn_I1262 | Uridine phosphorylase Udp; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (258 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (336 aa) |
| | ackA | Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa) |
| | bhn_I1148 | Sodium ion-pumping decarboxylase alpha subunit. (476 aa) |
| | bhn_I1100 | Hexapeptide-repeat-containing transferase. (224 aa) |
| | bhn_I1059 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (473 aa) |
| | bhn_I0895 | ATP-NAD kinase. (280 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (616 aa) |
| | bhn_I0892 | Geranylgeranyl pyrophosphate synthase. (308 aa) |
| | bhn_I0878 | Riboflavin biosynthesis protein RibF. (302 aa) |
| | bhn_I0728 | PurE-related protein. (256 aa) |
| | bhn_I0709 | Phosphoribulokinase/uridine kinase family protein. (246 aa) |
| | bhn_I0672 | 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. (392 aa) |
| | bhn_I0671 | IMP cyclohydrolase PurO. (235 aa) |
| | bhn_I0624 | RelA/SpoT domain-containing protein. (245 aa) |
| | bhn_I0610 | Hypothetical protein. (44 aa) |
| | bhn_I0566 | Metallo-beta-lactamase superfamily hydrolase. (272 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (235 aa) |
| | bhn_I0545 | RelA/SpoT domain-containing protein. (217 aa) |
| | bhn_I0519 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD. (237 aa) |
| | udk | Uridine kinase Udk. (205 aa) |
| | bhn_I0504 | Hypothetical protein. (427 aa) |
| | bhn_I0396 | 1-acylglycerol-3-phosphate O-acyltransferase. (247 aa) |
| | tdk | Thymidine kinase Tdk. (201 aa) |
| | bhn_I0371 | Pyridoxamine 5-phosphate oxidase. (130 aa) |
| | bhn_I0343 | NUDIX family hydrolase. (175 aa) |
| | bhn_I0339 | Phosphomethylpyrimidine kinase. (287 aa) |
| | coaX | Pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (271 aa) |
| | atpC | ATP synthase F1 epsilon subunit AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane. (142 aa) |
| | atpD | ATP synthase F1 beta subunit AtpD; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (464 aa) |
| | atpG | ATP synthase F1 gamma subunit AtpG; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (286 aa) |
| | atpA | ATP synthase F1 alpha subunit AtpA; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (506 aa) |
| | atpH | ATP synthase F1 delta subunit AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (179 aa) |
| | bhn_I0158 | ATP synthase F0 B subunit AtpF. (178 aa) |
| | atpE | ATP synthase F0 C subunit AtpE; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (93 aa) |
| | atpB | ATP synthase F0 A subunit AtpB; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (256 aa) |
| | bhn_I0128 | Adenosine deaminase Add. (825 aa) |
| | pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (351 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa) |
