(5 nodes) Fumarate hydratase activity, and Malic oxidoreductase network (Pseudomonas silesiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANJ53886.1	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
	fumC	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
	ANJ55372.1	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
	ANJ57954.1	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
	aspA	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)

Your Current Organism:

Pseudomonas silesiensis

NCBI taxonomy Id: 1853130
Other names: DSM 103370, P. silesiensis, PCM 2856, Pseudomonas silesiensis Kaminski et al. 2018, Pseudomonas sp. A3(2016), strain A3

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANJ53886.1	ANJ55372.1	PMA3_01470	PMA3_09515	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
ANJ53886.1	ANJ57954.1	PMA3_01470	PMA3_23445	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.957
ANJ53886.1	aspA	PMA3_01470	PMA3_25125	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.940
ANJ53886.1	fumC	PMA3_01470	PMA3_06890	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.940
ANJ55372.1	ANJ53886.1	PMA3_09515	PMA3_01470	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
ANJ55372.1	ANJ57954.1	PMA3_09515	PMA3_23445	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.957
ANJ55372.1	aspA	PMA3_09515	PMA3_25125	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.940
ANJ55372.1	fumC	PMA3_09515	PMA3_06890	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.940
ANJ57954.1	ANJ53886.1	PMA3_23445	PMA3_01470	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
ANJ57954.1	ANJ55372.1	PMA3_23445	PMA3_09515	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
ANJ57954.1	aspA	PMA3_23445	PMA3_25125	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.966
ANJ57954.1	fumC	PMA3_23445	PMA3_06890	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.966
aspA	ANJ53886.1	PMA3_25125	PMA3_01470	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.940
aspA	ANJ55372.1	PMA3_25125	PMA3_09515	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.940
aspA	ANJ57954.1	PMA3_25125	PMA3_23445	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.966
aspA	fumC	PMA3_25125	PMA3_06890	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.907
fumC	ANJ53886.1	PMA3_06890	PMA3_01470	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.940
fumC	ANJ55372.1	PMA3_06890	PMA3_09515	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.940
fumC	ANJ57954.1	PMA3_06890	PMA3_23445	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.966
fumC	aspA	PMA3_06890	PMA3_25125	Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.907