STRINGSTRING
thrB thrB ANJ53981.1 ANJ53981.1 ANJ59270.1 ANJ59270.1 ANJ54457.1 ANJ54457.1 ANJ54684.1 ANJ54684.1 ANJ54686.1 ANJ54686.1 asd asd ANJ55288.1 ANJ55288.1 ANJ55389.1 ANJ55389.1 ANJ55392.1 ANJ55392.1 ANJ59306.1 ANJ59306.1 ANJ55501.1 ANJ55501.1 ANJ55589.1 ANJ55589.1 ANJ56969.1 ANJ56969.1 thrH thrH dapA dapA ANJ57903.1 ANJ57903.1 ANJ58206.1 ANJ58206.1 dapB dapB ANJ58485.1 ANJ58485.1 ANJ58487.1 ANJ58487.1 glyA-3 glyA-3 ANJ58782.1 ANJ58782.1 ANJ58805.1 ANJ58805.1 ilvA ilvA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thrBHomoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (316 aa)
ANJ53981.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
ANJ59270.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
ANJ54457.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
ANJ54684.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ANJ54686.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (413 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (370 aa)
ANJ55288.1Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa)
ANJ55389.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (297 aa)
ANJ55392.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
ANJ59306.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
ANJ55501.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (297 aa)
ANJ55589.1Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
ANJ56969.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
thrHPhosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Catalyzes the formation of serine from phosphoserine; also has phosphoserine:homoserine phosphotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
ANJ57903.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
ANJ58206.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
ANJ58485.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
ANJ58487.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ANJ58782.1Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa)
ANJ58805.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
ilvAPLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
Your Current Organism:
Pseudomonas silesiensis
NCBI taxonomy Id: 1853130
Other names: DSM 103370, P. silesiensis, PCM 2856, Pseudomonas silesiensis Kaminski et al. 2018, Pseudomonas sp. A3(2016), strain A3
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