STRINGSTRING
ANJ54731.1 ANJ54731.1 ANJ53747.1 ANJ53747.1 ANJ53981.1 ANJ53981.1 glyA glyA ANJ54609.1 ANJ54609.1 ANJ54684.1 ANJ54684.1 cysB cysB metZ metZ PMA3_09645 PMA3_09645 ANJ56021.1 ANJ56021.1 ANJ56396.1 ANJ56396.1 ANJ56704.1 ANJ56704.1 ANJ56705.1 ANJ56705.1 glyA-2 glyA-2 ANJ59411.1 ANJ59411.1 serS serS selD selD thrH thrH cysH cysH serC serC ANJ57729.1 ANJ57729.1 ANJ58110.1 ANJ58110.1 ANJ58152.1 ANJ58152.1 cysZ cysZ ANJ58490.1 ANJ58490.1 glyA-3 glyA-3 ANJ58917.1 ANJ58917.1 ANJ58919.1 ANJ58919.1 ANJ58943.1 ANJ58943.1 ANJ58944.1 ANJ58944.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANJ54731.1Cysteine synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa)
ANJ53747.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
ANJ53981.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ANJ54609.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ANJ54684.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
cysBLysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (403 aa)
PMA3_09645L-asparagine permease; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
ANJ56021.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
ANJ56396.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ANJ56704.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
ANJ56705.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
ANJ59411.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
selDSelenide,water dikinase SelD; Synthesizes selenophosphate from selenide and ATP. (344 aa)
thrHPhosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Catalyzes the formation of serine from phosphoserine; also has phosphoserine:homoserine phosphotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (246 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
ANJ57729.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa)
ANJ58110.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
ANJ58152.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (383 aa)
cysZSulfate transporter CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (250 aa)
ANJ58490.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ANJ58917.1Phosphorylcholine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ANJ58919.1Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (170 aa)
ANJ58943.1FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
ANJ58944.1D-3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
Your Current Organism:
Pseudomonas silesiensis
NCBI taxonomy Id: 1853130
Other names: DSM 103370, P. silesiensis, PCM 2856, Pseudomonas silesiensis Kaminski et al. 2018, Pseudomonas sp. A3(2016), strain A3
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