STRINGSTRING
speA speA ANJ59141.1 ANJ59141.1 purK purK ubiC ubiC ANJ59077.1 ANJ59077.1 lysA lysA ubiD ubiD ANJ58823.1 ANJ58823.1 ANJ58782.1 ANJ58782.1 ANJ58716.1 ANJ58716.1 trpE trpE ANJ58689.1 ANJ58689.1 trpC trpC ribB-2 ribB-2 ubiX-2 ubiX-2 ANJ58449.1 ANJ58449.1 ANJ58448.1 ANJ58448.1 ANJ58447.1 ANJ58447.1 ANJ58322.1 ANJ58322.1 folX folX ANJ58068.1 ANJ58068.1 ANJ57877.1 ANJ57877.1 ANJ57565.1 ANJ57565.1 cobD cobD ANJ57519.1 ANJ57519.1 prpB prpB ANJ57397.1 ANJ57397.1 ANJ57239.1 ANJ57239.1 ANJ57118.1 ANJ57118.1 menB menB ANJ56950.1 ANJ56950.1 ANJ56836.1 ANJ56836.1 moaA moaA ANJ56448.1 ANJ56448.1 ANJ56308.1 ANJ56308.1 ANJ56142.1 ANJ56142.1 ANJ56141.1 ANJ56141.1 ANJ55953.1 ANJ55953.1 ANJ55916.1 ANJ55916.1 ANJ55781.1 ANJ55781.1 ANJ55762.1 ANJ55762.1 ribB ribB ANJ55501.1 ANJ55501.1 ANJ55484.1 ANJ55484.1 ubiX ubiX ANJ55420.1 ANJ55420.1 ANJ59301.1 ANJ59301.1 ANJ55305.1 ANJ55305.1 ANJ55303.1 ANJ55303.1 ANJ55168.1 ANJ55168.1 ANJ55070.1 ANJ55070.1 ANJ54873.1 ANJ54873.1 ANJ54856.1 ANJ54856.1 ANJ54791.1 ANJ54791.1 pyrF pyrF ANJ54684.1 ANJ54684.1 ANJ54494.1 ANJ54494.1 ppc ppc ANJ59267.1 ANJ59267.1 psd psd thiC thiC hemE hemE pckA pckA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)
ANJ59141.1Pyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa)
ubiCChorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (187 aa)
ANJ59077.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa)
ubiD3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (488 aa)
ANJ58823.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
ANJ58782.1Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa)
ANJ58716.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa)
trpEAnthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (493 aa)
ANJ58689.1Anthranilate synthase component 2; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
trpCIndole-3-glycerol-phosphate synthase; Involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (278 aa)
ribB-23,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (363 aa)
ubiX-2Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (210 aa)
ANJ58449.1Dimethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
ANJ58448.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
ANJ58447.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
ANJ58322.1Ornithine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (387 aa)
folXD-erythro-7,8-dihydroneopterin triphosphate epimerase; Catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
ANJ58068.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (333 aa)
ANJ57877.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
ANJ57565.1Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (591 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (302 aa)
ANJ57519.1Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (296 aa)
ANJ57397.1Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (163 aa)
ANJ57239.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
ANJ57118.14-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
menB1,4-dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (260 aa)
ANJ56950.14-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (340 aa)
ANJ56836.1Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily. (289 aa)
moaACyclic pyranopterin phosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (330 aa)
ANJ56448.1Lysine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (751 aa)
ANJ56308.1Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (591 aa)
ANJ56142.1Phosphonopyruvate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
ANJ56141.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
ANJ55953.1Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (365 aa)
ANJ55916.1Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (792 aa)
ANJ55781.14-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (342 aa)
ANJ55762.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
ribB3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (368 aa)
ANJ55501.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (297 aa)
ANJ55484.15-keto-4-deoxy-D-glucarate aldolase; Cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (266 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (207 aa)
ANJ55420.13-octaprenyl-4-hydroxybenzoate carboxy-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiD family. (477 aa)
ANJ59301.1S-adenosylmethionine--2-demethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
ANJ55305.1Siderophore biosynthesis protein SbnG; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (257 aa)
ANJ55303.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
ANJ55168.1hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
ANJ55070.1OHCU decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
ANJ54873.12-dehydro-3-deoxy-6-phosphogalactonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
ANJ54856.1Radical SAM protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa)
ANJ54791.1Aminodeoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (244 aa)
ANJ54684.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ANJ54494.12-methylisocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (876 aa)
ANJ59267.1Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family. (481 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (286 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (629 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)
Your Current Organism:
Pseudomonas silesiensis
NCBI taxonomy Id: 1853130
Other names: DSM 103370, P. silesiensis, PCM 2856, Pseudomonas silesiensis Kaminski et al. 2018, Pseudomonas sp. A3(2016), strain A3
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.