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purU purU metN metN metN-2 metN-2 ANJ53981.1 ANJ53981.1 ilvH ilvH ANJ59270.1 ANJ59270.1 glnD glnD ANJ54686.1 ANJ54686.1 relA relA purU-2 purU-2 ANJ57492.1 ANJ57492.1 ANJ57650.1 ANJ57650.1 ANJ57774.1 ANJ57774.1 purU-3 purU-3 ANJ57978.1 ANJ57978.1 ANJ58756.1 ANJ58756.1 purU-4 purU-4 ilvA ilvA ANJ58944.1 ANJ58944.1 ANJ59089.1 ANJ59089.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (288 aa)
metNMethionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (335 aa)
metN-2ABC transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (377 aa)
ANJ53981.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
ilvHAcetolactate synthase small subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
ANJ59270.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
glnDBifunctional uridylyltransferase/uridylyl-removing protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (900 aa)
ANJ54686.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (413 aa)
relA(p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (747 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (288 aa)
ANJ57492.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ANJ57650.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
ANJ57774.1Glycine cleavage system protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
purU-3Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa)
ANJ57978.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
ANJ58756.1Glycine cleavage system protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
purU-4Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (285 aa)
ilvAPLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
ANJ58944.1D-3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
ANJ59089.1(p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (701 aa)
Your Current Organism:
Pseudomonas silesiensis
NCBI taxonomy Id: 1853130
Other names: DSM 103370, P. silesiensis, PCM 2856, Pseudomonas silesiensis Kaminski et al. 2018, Pseudomonas sp. A3(2016), strain A3
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