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gpmI gpmI fbp fbp ANJ53981.1 ANJ53981.1 glyA glyA acsA acsA ANJ54346.1 ANJ54346.1 ppc ppc eno eno ANJ54545.1 ANJ54545.1 ANJ54546.1 ANJ54546.1 acsA-2 acsA-2 ANJ55454.1 ANJ55454.1 ANJ55661.1 ANJ55661.1 ANJ55662.1 ANJ55662.1 ANJ55663.1 ANJ55663.1 ANJ55668.1 ANJ55668.1 ackA ackA ANJ56142.1 ANJ56142.1 ANJ56164.1 ANJ56164.1 ANJ56165.1 ANJ56165.1 ANJ56166.1 ANJ56166.1 ANJ56167.1 ANJ56167.1 gfa gfa ANJ56347.1 ANJ56347.1 glyA-2 glyA-2 ANJ57074.1 ANJ57074.1 ANJ57140.1 ANJ57140.1 ANJ57358.1 ANJ57358.1 ANJ57399.1 ANJ57399.1 thrH thrH serC serC ANJ57568.1 ANJ57568.1 ANJ58126.1 ANJ58126.1 ANJ58127.1 ANJ58127.1 ANJ58128.1 ANJ58128.1 ANJ58129.1 ANJ58129.1 ANJ58242.1 ANJ58242.1 ANJ58774.1 ANJ58774.1 glyA-3 glyA-3 ANJ58823.1 ANJ58823.1 ANJ58944.1 ANJ58944.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa)
fbpFructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (336 aa)
ANJ53981.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
ANJ54346.1Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (876 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
ANJ54545.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
ANJ54546.1S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (281 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
ANJ55454.1Glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
ANJ55661.1Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
ANJ55662.1Protein glxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
ANJ55663.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (445 aa)
ANJ55668.1Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
ANJ56142.1Phosphonopyruvate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
ANJ56164.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
ANJ56165.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (808 aa)
ANJ56166.1Formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (311 aa)
ANJ56167.1Formate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
gfaGlutathione-dependent formaldehyde-activating protein; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (192 aa)
ANJ56347.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
ANJ57074.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
ANJ57140.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ANJ57358.1Quinohemoprotein amine dehydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (526 aa)
ANJ57399.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
thrHPhosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Catalyzes the formation of serine from phosphoserine; also has phosphoserine:homoserine phosphotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
ANJ57568.1Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
ANJ58126.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
ANJ58127.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
ANJ58128.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (960 aa)
ANJ58129.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
ANJ58242.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (699 aa)
ANJ58774.1Formaldehyde dehydrogenase, glutathione-independent; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ANJ58823.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
ANJ58944.1D-3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
Your Current Organism:
Pseudomonas silesiensis
NCBI taxonomy Id: 1853130
Other names: DSM 103370, P. silesiensis, PCM 2856, Pseudomonas silesiensis Kaminski et al. 2018, Pseudomonas sp. A3(2016), strain A3
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