STRINGSTRING
Tb927.4.2720 Tb927.4.2720 Tb927.5.1150 Tb927.5.1150 Tb927.2.2180 Tb927.2.2180 Tb11.01.8320 Tb11.01.8320 Tb11.01.8290 Tb11.01.8290 Tb11.01.7680 Tb11.01.7680 Tb11.01.5500 Tb11.01.5500 Tb11.01.5370 Tb11.01.5370 Tb11.01.3850 Tb11.01.3850 Tb11.01.2820 Tb11.01.2820 Tb11.01.2250 Tb11.01.2250 Tb11.01.0820 Tb11.01.0820 Tb11.01.0260 Tb11.01.0260 Tb11.01.0280 Tb11.01.0280 Tb11.01.0290 Tb11.01.0290 Tb11.01.0490 Tb11.01.0490 Tb11.02.5380 Tb11.02.5380 Tb11.02.4920 Tb11.02.4920 Tb11.02.4620 Tb11.02.4620 Tb11.02.4220 Tb11.02.4220 Tb11.02.2620 Tb11.02.2620 Tb11.02.1720 Tb11.02.1720 Tb11.02.0620 Tb11.02.0620 Tb11.02.0570 Tb11.02.0570 Tb11.02.0380 Tb11.02.0380 Tb11.02.0240 Tb11.02.0240 Tb11.02.0110 Tb11.02.0110 Tb11.18.0014 Tb11.18.0014 Tb11.03.0050 Tb11.03.0050 Tb11.03.0680 Tb11.03.0680 Tb10.61.0490 Tb10.61.0490 Tb10.61.1030 Tb10.61.1030 Tb10.61.1340 Tb10.61.1340 Tb10.61.1780 Tb10.61.1780 Tb10.61.1920 Tb10.61.1920 Tb10.61.1990 Tb10.61.1990 Tb10.61.2040 Tb10.61.2040 Tb10.61.2440 Tb10.61.2440 Tb10.389.0160 Tb10.389.0160 Tb10.389.0280 Tb10.389.0280 Tb10.389.1290 Tb10.389.1290 Tb10.389.1790 Tb10.389.1790 Tb10.406.0540 Tb10.406.0540 Tb10.6k15.0270 Tb10.6k15.0270 Tb10.6k15.0360 Tb10.6k15.0360 Tb10.6k15.0530 Tb10.6k15.0530 Tb10.6k15.2320 Tb10.6k15.2320 Tb10.6k15.2760 Tb10.6k15.2760 Tb10.6k15.3160 Tb10.6k15.3160 Tb10.6k15.3210 Tb10.6k15.3210 Tb10.6k15.3220 Tb10.6k15.3220 Tb10.6k15.3410 Tb10.6k15.3410 Tb10.70.0510 Tb10.70.0510 Tb10.70.0540 Tb10.70.0540 Tb10.70.0570 Tb10.70.0570 Tb10.70.3570 Tb10.70.3570 Tb10.70.4960 Tb10.70.4960 Tb09.244.2650 Tb09.244.2650 Tb09.244.2790 Tb09.244.2790 Tb09.211.4870 Tb09.211.4870 Tb09.211.4190 Tb09.211.4190 Tb09.211.3670 Tb09.211.3670 Tb09.211.2550 Tb09.211.2550 Tb09.211.2300 Tb09.211.2300 Tb09.211.0180 Tb09.211.0180 Tb09.160.5160 Tb09.160.5160 Tb09.160.3820 Tb09.160.3820 Tb09.160.3670 Tb09.160.3670 Tb09.160.1560 Tb09.160.1560 TbEAP1 TbEAP1 TB927.1.1700 TB927.1.1700 TB927.1.1370 TB927.1.1370 TB927.1.560 TB927.1.560 Tb927.8.6770 Tb927.8.6770 Tb927.7.7450 Tb927.7.7450 Tb927.7.270 Tb927.7.270 Tb927.8.5040 Tb927.8.5040 Tb927.7.4220 Tb927.7.4220 Tb927.7.4340 Tb927.7.4340 Tb927.5.1560 Tb927.5.1560 Tb927.5.1200 Tb927.5.1200 Tb927.7.700 Tb927.7.700 Tb927.8.4450 Tb927.8.4450 Tb927.8.4170 Tb927.8.4170 Tb927.5.1080 Tb927.5.1080 Tb927.3.3590 Tb927.3.3590 Tb927.7.3380 Tb927.7.3380 Tb927.3.620 Tb927.3.620 Tb927.8.5490 Tb927.8.5490 Tb927.7.4670 Tb927.7.4670 Tb927.8.2600 Tb927.8.2600 Tb927.4.4170 Tb927.4.4170 Tb927.5.4310 Tb927.5.4310 Tb927.5.4270 Tb927.5.4270 Tb927.5.3260 Tb927.5.3260 Tb927.3.2830 Tb927.3.2830 Tb927.5.2660 Tb927.5.2660 Tb927.8.3750 Tb927.8.3750 Tb927.4.1630 Tb927.4.1630 Tb927.8.1980 Tb927.8.1980 Tb927.5.2530 Tb927.5.2530 Tb927.7.5640 Tb927.7.5640 Tb927.3.4600 Tb927.3.4600 Tb927.3.2470 Tb927.3.2470 Tb927.4.3840 Tb927.4.3840 Tb927.4.3850 Tb927.4.3850 Tb927.6.2780 Tb927.6.2780 Tb927.6.2650 Tb927.6.2650 Tb927.6.670 Tb927.6.670 Tb927.4.2630 Tb927.4.2630 Tb927.6.2050 Tb927.6.2050 Tb927.4.3670 Tb927.4.3670 Tb927.6.1610 Tb927.6.1610 Tb927.2.4550 Tb927.2.4550 Tb927.2.4980 Tb927.2.4980 Tb927.6.4350 Tb927.6.4350 Tb927.6.4600 Tb927.6.4600 Tb927.2.2950 Tb927.2.2950
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tb927.4.2720Uncharacterized protein. (739 aa)
Tb927.5.1150Pre-mRNA splicing factor ATP-dependent RNA helicase, putative. (735 aa)
Tb927.2.2180Ribosomal RNA processing protein 41B. (256 aa)
Tb11.01.8320Exosome-associated protein 2. (294 aa)
Tb11.01.8290ATP-dependent DEAD/H RNA helicase, putative. (569 aa)
Tb11.01.7680RNA-binding protein, putative. (433 aa)
Tb11.01.5500U3 small nucleolar ribonucleoprotein protein IMP3, putative. (226 aa)
Tb11.01.5370ATP-dependent DEAD/H RNA helicase, putative. (556 aa)
Tb11.01.3850Uncharacterized protein. (389 aa)
Tb11.01.2820Exosome-associated protein 4. (227 aa)
Tb11.01.2250Uncharacterized protein. (975 aa)
Tb11.01.0820Uncharacterized protein. (1216 aa)
Tb11.01.0260Exosome complex exonuclease RRP44, putative; Belongs to the RNR ribonuclease family. (895 aa)
Tb11.01.0280WD_REPEATS_REGION domain-containing protein. (805 aa)
Tb11.01.0290Carbonic anhydrase-like protein. (422 aa)
Tb11.01.0490Sas10 domain-containing protein. (523 aa)
Tb11.02.5380Exosome complex exonuclease RRP44p homologue; Belongs to the RNR ribonuclease family. (972 aa)
Tb11.02.4920ATP-dependent DEAD/H RNA helicase, putative. (550 aa)
Tb11.02.4620Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (781 aa)
Tb11.02.422060S ribosomal protein L24, putative. (191 aa)
Tb11.02.2620ATP-dependent DEAD/H RNA helicase, putative. (601 aa)
Tb11.02.1720Uncharacterized protein. (1201 aa)
Tb11.02.0620Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (655 aa)
Tb11.02.0570WD_REPEATS_REGION domain-containing protein. (576 aa)
Tb11.02.0380WD_REPEATS_REGION domain-containing protein. (769 aa)
Tb11.02.0240GTP-binding protein, putative. (486 aa)
Tb11.02.0110NUC173 domain-containing protein. (1292 aa)
Tb11.18.0014CBF domain-containing protein. (788 aa)
Tb11.03.0050RNA processing factor 1, putative. (331 aa)
Tb11.03.0680Uncharacterized protein. (948 aa)
Tb10.61.0490PINc domain-containing protein. (207 aa)
Tb10.61.1030U3 snoRNA-associated protein UTP11, putative. (346 aa)
Tb10.61.1340Uncharacterized protein. (695 aa)
Tb10.61.1780Uncharacterized protein. (681 aa)
Tb10.61.1920Fibrillarin, putative. (304 aa)
Tb10.61.1990Ribosome biogenesis protein, putative. (307 aa)
Tb10.61.2040Fibrillarin, putative. (228 aa)
Tb10.61.2440Uncharacterized protein. (1040 aa)
Tb10.389.0160Periodic tryptophan protein 2, putative. (939 aa)
Tb10.389.0280Uncharacterized protein. (1236 aa)
Tb10.389.1290Uncharacterized protein. (649 aa)
Tb10.389.179060S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (215 aa)
Tb10.406.0540ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (520 aa)
Tb10.6k15.0270Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (226 aa)
Tb10.6k15.0360Uncharacterized protein. (410 aa)
Tb10.6k15.0530ATP-dependent DEAD/H RNA helicase, putative. (878 aa)
Tb10.6k15.2320Uncharacterized protein. (269 aa)
Tb10.6k15.2760Uncharacterized protein. (712 aa)
Tb10.6k15.3160Fibrillarin. (300 aa)
Tb10.6k15.3210Exosome complex exonuclease RRP41A. (252 aa)
Tb10.6k15.3220ATP-dependent DEAD/H RNA helicase, putative. (950 aa)
Tb10.6k15.3410Pre-mRNA splicing factor ATP-dependent RNA helicase, putative. (1062 aa)
Tb10.70.0510Uncharacterized protein. (613 aa)
Tb10.70.0540ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (512 aa)
Tb10.70.0570ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (604 aa)
Tb10.70.3570DRIM domain-containing protein. (3901 aa)
Tb10.70.4960WD_REPEATS_REGION domain-containing protein. (696 aa)
Tb09.244.2650Uncharacterized protein. (897 aa)
Tb09.244.2790rRNA processing protein, putative. (251 aa)
Tb09.211.4870RNA 3'-terminal phosphate cyclase-like protein. (362 aa)
Tb09.211.4190Uncharacterized protein. (311 aa)
Tb09.211.3670CCHC-type domain-containing protein. (390 aa)
Tb09.211.2550WD_REPEATS_REGION domain-containing protein. (444 aa)
Tb09.211.2300RNA helicase. (795 aa)
Tb09.211.0180Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (658 aa)
Tb09.160.5160Exosome complex exonuclease RRP40. (304 aa)
Tb09.160.3820Nucleolar RNA binding protein, putative. (501 aa)
Tb09.160.3670Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
Tb09.160.1560Uncharacterized protein. (2631 aa)
TbEAP1RNasePH-like protein exosome-associated protein 1 Rrp42 homologue. (397 aa)
TB927.1.1700AATF-Che1 domain-containing protein. (493 aa)
TB927.1.1370rRNA biogenesis protein, putative. (679 aa)
TB927.1.560Uncharacterized protein. (442 aa)
Tb927.8.6770WD_REPEATS_REGION domain-containing protein. (419 aa)
Tb927.7.7450Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (601 aa)
Tb927.7.270Ribosome biogenesis protein, putative. (370 aa)
Tb927.8.5040Uncharacterized protein. (278 aa)
Tb927.7.4220Uncharacterized protein. (1110 aa)
Tb927.7.4340Uncharacterized protein. (855 aa)
Tb927.5.1560ATP-dependent DEAD/H RNA helicase, putative. (753 aa)
Tb927.5.1200Exosome component CSL4. (309 aa)
Tb927.7.700Uncharacterized protein. (666 aa)
Tb927.8.4450RNA-binding protein, putative. (428 aa)
Tb927.8.4170RNA-binding protein, putative. (857 aa)
Tb927.5.1080RRM domain-containing protein. (237 aa)
Tb927.3.3590U3 small nucleolar ribonucleoprotein protein MPP10, putative. (672 aa)
Tb927.7.3380Protein MAK16 homolog; Belongs to the MAK16 family. (276 aa)
Tb927.3.620RNA helicase. (808 aa)
Tb927.8.5490Uncharacterized protein. (623 aa)
Tb927.7.4670Ribosomal RNA processing protein 4. (324 aa)
Tb927.8.2600WD_REPEATS_REGION domain-containing protein. (646 aa)
Tb927.4.4170rRNA methyltransferase, putative. (284 aa)
Tb927.5.4310GTP-binding protein, putative. (814 aa)
Tb927.5.4270RNA helicase. (828 aa)
Tb927.5.3260WD_REPEATS_REGION domain-containing protein. (1399 aa)
Tb927.3.2830Peter pan protein, putative. (364 aa)
Tb927.5.2660Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (860 aa)
Tb927.8.3750Nucleolar protein, putative. (483 aa)
Tb927.4.1630Ribosomal RNA processing protein 6. (736 aa)
Tb927.8.1980WD_REPEATS_REGION domain-containing protein. (477 aa)
Tb927.5.2530RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1039 aa)
Tb927.7.5640G-patch domain-containing protein. (271 aa)
Tb927.3.4600Uncharacterized protein. (1079 aa)
Tb927.3.2470Pumilio/PUF RNA binding protein 8, putative. (604 aa)
Tb927.4.3840Nucleolar protein, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (525 aa)
Tb927.4.3850WD_REPEATS_REGION domain-containing protein. (453 aa)
Tb927.6.2780U3 small nuclear ribonucleoprotein (SnRNP), putative. (287 aa)
Tb927.6.2650MI domain-containing protein. (757 aa)
Tb927.6.670Ribosomal RNA processing protein 45. (363 aa)
Tb927.4.2630ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (843 aa)
Tb927.6.2050Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (213 aa)
Tb927.4.3670CBF domain-containing protein. (457 aa)
Tb927.6.1610rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (344 aa)
Tb927.2.4550Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (905 aa)
Tb927.2.4980Uncharacterized protein. (279 aa)
Tb927.6.4350KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (325 aa)
Tb927.6.4600Pre-mRNA splicing factor ATP-dependent RNA helicase, putative. (1009 aa)
Tb927.2.2950Uncharacterized protein. (980 aa)
Your Current Organism:
Trypanosoma brucei
NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927
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