Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SIR2rp1 | SIR2rp2 | Q57V41 | Q57YZ9 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | NAD-dependent protein deacylase SIR2rp2; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. | 0.733 |
| SIR2rp1 | SIR2rp3 | Q57V41 | Q584D5 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | 0.978 |
| SIR2rp1 | Tb10.26.0320 | Q57V41 | Q389I2 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | Nicotinate phosphoribosyltransferase, putative. | 0.406 |
| SIR2rp1 | Tb11.01.6500 | Q57V41 | Q381U8 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | NAD+ synthase, putative. | 0.932 |
| SIR2rp1 | Tb927.5.2640 | Q57V41 | Q57ZU0 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | CTP_transf_like domain-containing protein. | 0.931 |
| SIR2rp1 | Tb927.7.5080 | Q57V41 | Q57ZI1 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | ATP-NAD kinase-like protein. | 0.928 |
| SIR2rp2 | SIR2rp1 | Q57YZ9 | Q57V41 | NAD-dependent protein deacylase SIR2rp2; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | 0.733 |
| SIR2rp2 | SIR2rp3 | Q57YZ9 | Q584D5 | NAD-dependent protein deacylase SIR2rp2; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | 0.638 |
| SIR2rp2 | Tb10.26.0320 | Q57YZ9 | Q389I2 | NAD-dependent protein deacylase SIR2rp2; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. | Nicotinate phosphoribosyltransferase, putative. | 0.406 |
| SIR2rp3 | SIR2rp1 | Q584D5 | Q57V41 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | 0.978 |
| SIR2rp3 | SIR2rp2 | Q584D5 | Q57YZ9 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | NAD-dependent protein deacylase SIR2rp2; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. | 0.638 |
| SIR2rp3 | Tb09.160.2540 | Q584D5 | Q38FD5 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | Pyrazinamidase/nicotinamidase, putative. | 0.490 |
| SIR2rp3 | Tb10.26.0320 | Q584D5 | Q389I2 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | Nicotinate phosphoribosyltransferase, putative. | 0.432 |
| SIR2rp3 | Tb11.01.6500 | Q584D5 | Q381U8 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | NAD+ synthase, putative. | 0.932 |
| SIR2rp3 | Tb11.02.0710 | Q584D5 | Q386J1 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | Histone-lysine N-methyltransferase, H3 lysine-79 specific. | 0.436 |
| SIR2rp3 | Tb927.5.2640 | Q584D5 | Q57ZU0 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | CTP_transf_like domain-containing protein. | 0.945 |
| SIR2rp3 | Tb927.7.5080 | Q584D5 | Q57ZI1 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | ATP-NAD kinase-like protein. | 0.932 |
| SIR2rp3 | Tb927.8.1920 | Q584D5 | Q581Z0 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | Histone-lysine N-methyltransferase, H3 lysine-79 specific. | 0.436 |
| Tb09.160.2540 | SIR2rp3 | Q38FD5 | Q584D5 | Pyrazinamidase/nicotinamidase, putative. | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | 0.490 |
| Tb09.160.2540 | Tb10.26.0320 | Q38FD5 | Q389I2 | Pyrazinamidase/nicotinamidase, putative. | Nicotinate phosphoribosyltransferase, putative. | 0.819 |
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