node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIR2rp1 | SIR2rp3 | Q57V41 | Q584D5 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | 0.978 |
SIR2rp1 | Tb11.01.6500 | Q57V41 | Q381U8 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | NAD+ synthase, putative. | 0.932 |
SIR2rp1 | Tb927.5.2640 | Q57V41 | Q57ZU0 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | CTP_transf_like domain-containing protein. | 0.931 |
SIR2rp1 | Tb927.7.5080 | Q57V41 | Q57ZI1 | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | ATP-NAD kinase-like protein. | 0.928 |
SIR2rp3 | SIR2rp1 | Q584D5 | Q57V41 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | 0.978 |
SIR2rp3 | Tb11.01.6500 | Q584D5 | Q381U8 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | NAD+ synthase, putative. | 0.932 |
SIR2rp3 | Tb927.5.2640 | Q584D5 | Q57ZU0 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | CTP_transf_like domain-containing protein. | 0.945 |
SIR2rp3 | Tb927.7.5080 | Q584D5 | Q57ZI1 | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | ATP-NAD kinase-like protein. | 0.932 |
Tb11.01.6500 | SIR2rp1 | Q381U8 | Q57V41 | NAD+ synthase, putative. | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | 0.932 |
Tb11.01.6500 | SIR2rp3 | Q381U8 | Q584D5 | NAD+ synthase, putative. | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | 0.932 |
Tb11.01.6500 | Tb927.5.2640 | Q381U8 | Q57ZU0 | NAD+ synthase, putative. | CTP_transf_like domain-containing protein. | 0.963 |
Tb11.01.6500 | Tb927.7.5080 | Q381U8 | Q57ZI1 | NAD+ synthase, putative. | ATP-NAD kinase-like protein. | 0.961 |
Tb927.5.2640 | SIR2rp1 | Q57ZU0 | Q57V41 | CTP_transf_like domain-containing protein. | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | 0.931 |
Tb927.5.2640 | SIR2rp3 | Q57ZU0 | Q584D5 | CTP_transf_like domain-containing protein. | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | 0.945 |
Tb927.5.2640 | Tb11.01.6500 | Q57ZU0 | Q381U8 | CTP_transf_like domain-containing protein. | NAD+ synthase, putative. | 0.963 |
Tb927.5.2640 | Tb927.7.5080 | Q57ZU0 | Q57ZI1 | CTP_transf_like domain-containing protein. | ATP-NAD kinase-like protein. | 0.963 |
Tb927.7.5080 | SIR2rp1 | Q57ZI1 | Q57V41 | ATP-NAD kinase-like protein. | NAD-dependent protein deacetylase SIR2rp1; NAD-dependent protein deacetylase, which is involved in repression of RNA polymerase I-mediated expression immediately adjacent to telomeres. It is however not involved in antigenic variation and subtelomeric variant surface glycoprotein (VSG) gene silencing. Plays a role in DNA damage response. Also has ADP-ribosylation activity in vitro. | 0.928 |
Tb927.7.5080 | SIR2rp3 | Q57ZI1 | Q584D5 | ATP-NAD kinase-like protein. | NAD-dependent protein deacylase SIR2rp3; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo; Belongs to the sirtuin family. Class III subfamily. | 0.932 |
Tb927.7.5080 | Tb11.01.6500 | Q57ZI1 | Q381U8 | ATP-NAD kinase-like protein. | NAD+ synthase, putative. | 0.961 |
Tb927.7.5080 | Tb927.5.2640 | Q57ZI1 | Q57ZU0 | ATP-NAD kinase-like protein. | CTP_transf_like domain-containing protein. | 0.963 |