67 items (Trypanosoma brucei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KATNA1-2	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (680 aa)
	Tb927.6.1290	Uncharacterized protein. (899 aa)
	Tb927.6.3570	Tubulin-tyrosine ligase-like protein, conserved. (633 aa)
	Tb927.6.5100	Serine/threonine-protein kinase, putative. (834 aa)
	Tb927.6.2400	Spindle pole body component. (669 aa)
	Tb927.4.2640	Uncharacterized protein. (1274 aa)
	Tb927.6.3090	Uncharacterized protein. (1621 aa)
	Tb927.3.2680	Ubiquitin-like domain-containing protein. (531 aa)
	Tb927.3.2210	Uncharacterized protein. (594 aa)
	Tb927.7.5650	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (638 aa)
	Tb927.4.1320	Uncharacterized protein. (908 aa)
	Tb927.3.5380	Uncharacterized protein. (517 aa)
	CFAP43	Cilia- and flagella-associated protein 43; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP43 family. (1460 aa)
	Tb927.8.1710	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (404 aa)
	Tb927.5.2950	Uncharacterized protein. (779 aa)
	Tb927.5.1870	AAA domain-containing protein; Belongs to the AAA ATPase family. (887 aa)
	Tb927.3.2020	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (746 aa)
	Tb927.8.6940	Uncharacterized protein. (1460 aa)
	Tb927.8.6200	Tubulin folding cofactor D, putative. (1343 aa)
	Tb927.4.3910	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (787 aa)
	Tb927.3.1440	AAA ATPase, putative. (814 aa)
	Tb927.8.8350	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (768 aa)
	CFAP44	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family. (1760 aa)
	Tb927.7.3330	Uncharacterized protein. (4334 aa)
	Tb927.3.3920	Serine/threonine-protein kinase, putative; Belongs to the protein kinase superfamily. (380 aa)
	Tb927.8.2890	Uncharacterized protein. (422 aa)
	Tb927.7.6310	Serine/threonine-protein kinase PLK. (768 aa)
	TB927.1.1150	Zeta tubulin; Belongs to the tubulin family. (480 aa)
	TB927.1.1550	Tubulin-tyrosine ligase, putative. (690 aa)
	TB927.1.2330	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
	TB927.1.2340	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	Tb10.70.6950	Epsilon tubulin; Belongs to the tubulin family. (487 aa)
	Tb09.160.0570	Protein kinase, putative. (650 aa)
	EB1	End-binding protein 1. (536 aa)
	Tb09.160.2260	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (691 aa)
	Tb09.211.1170	Tubulin tyrosine ligase protein, putative. (657 aa)
	Tb09.211.1400	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (482 aa)
	Tb09.211.1500	Katanin, putative. (538 aa)
	Tb10.70.7300	WD_REPEATS_REGION domain-containing protein. (1502 aa)
	Tb10.70.7180	TPR_REGION domain-containing protein. (1756 aa)
	Tb10.6k15.3980	GCP_N_terminal domain-containing protein. (1727 aa)
	Tb10.6k15.2920	Uncharacterized protein. (724 aa)
	Tb10.6k15.2670	Uncharacterized protein. (651 aa)
	Tb10.6k15.0540	Spindle pole body component. (784 aa)
	Tb10.6k15.0180	Uncharacterized protein. (822 aa)
	Tb10.05.0270	Uncharacterized protein. (1046 aa)
	Tb10.61.2720	Uncharacterized protein. (195 aa)
	Tb11.47.0006	Uncharacterized protein. (752 aa)
	Tb11.02.0590	LisH domain-containing protein. (151 aa)
	Tb11.02.0790	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (719 aa)
	Tb11.02.0860	ATPase_AAA_core domain-containing protein. (909 aa)
	Tb11.02.2260	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (690 aa)
	Tb11.02.2970	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (566 aa)
	Tb11.02.4640	Tubulin-tyrsoine ligase-like protein, putative. (980 aa)
	Tb11.01.0330	Protein kinase, putative; Belongs to the protein kinase superfamily. (309 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (554 aa)
	Tb11.01.2290	Protein kinase, putative. (1260 aa)
	Tb11.01.2530	Kinesin-like protein, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (617 aa)
	Tb11.01.2695	Delta tubulin; Belongs to the tubulin family. (489 aa)
	Tb11.01.3150	Spindle pole body component. (799 aa)
	Tb11.01.3720	Uncharacterized protein. (489 aa)
	Tb11.01.3730	Uncharacterized protein. (875 aa)
	Tb11.01.3990	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (916 aa)
	Tb11.01.5770	CLASP_N domain-containing protein. (965 aa)
	Tb11.01.6840	DUF4200 domain-containing protein. (682 aa)
	Tb927.4.2730	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (803 aa)
	Tb927.3.910	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (447 aa)

Your Current Organism:

Trypanosoma brucei

NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP43	CFAP44	Q580P9	Q57WH1	Cilia- and flagella-associated protein 43; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP43 family.	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	0.844
CFAP44	CFAP43	Q57WH1	Q580P9	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	Cilia- and flagella-associated protein 43; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP43 family.	0.844
CFAP44	Tb09.160.0570	Q57WH1	Q38FY2	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	Protein kinase, putative.	0.406
CFAP44	Tb11.01.0330	Q57WH1	Q384J7	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.406
CFAP44	Tb11.01.2290	Q57WH1	Q383M7	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	Protein kinase, putative.	0.527
CFAP44	Tb927.3.3920	Q57WH1	Q57WC8	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	Serine/threonine-protein kinase, putative; Belongs to the protein kinase superfamily.	0.406
CFAP44	Tb927.6.5100	Q57WH1	Q586I2	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	Serine/threonine-protein kinase, putative.	0.527
CFAP44	Tb927.7.6310	Q57WH1	Q57VI0	Cilia- and flagella-associated protein 44; Flagellar protein involved in flagellum axoneme organization and function; Belongs to the CFAP44 family.	Serine/threonine-protein kinase PLK.	0.527
EB1	TB927.1.1150	Q38FP4	Q4GZA3	End-binding protein 1.	Zeta tubulin; Belongs to the tubulin family.	0.716
EB1	TB927.1.2330	Q38FP4	Q4GYY6	End-binding protein 1.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.716
EB1	TB927.1.2340	Q38FP4	Q4GYY5	End-binding protein 1.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.915
EB1	Tb09.160.0570	Q38FP4	Q38FY2	End-binding protein 1.	Protein kinase, putative.	0.503
EB1	Tb10.70.6950	Q38FP4	Q4FKF8	End-binding protein 1.	Epsilon tubulin; Belongs to the tubulin family.	0.716
EB1	Tb11.01.0330	Q38FP4	Q384J7	End-binding protein 1.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.503
EB1	Tb11.01.2290	Q38FP4	Q383M7	End-binding protein 1.	Protein kinase, putative.	0.470
EB1	Tb11.01.5770	Q38FP4	Q382B9	End-binding protein 1.	CLASP_N domain-containing protein.	0.504
EB1	Tb927.3.3920	Q38FP4	Q57WC8	End-binding protein 1.	Serine/threonine-protein kinase, putative; Belongs to the protein kinase superfamily.	0.503
EB1	Tb927.6.3090	Q38FP4	Q583M5	End-binding protein 1.	Uncharacterized protein.	0.841
EB1	Tb927.6.5100	Q38FP4	Q586I2	End-binding protein 1.	Serine/threonine-protein kinase, putative.	0.470
EB1	Tb927.7.3330	Q38FP4	Q57WE8	End-binding protein 1.	Uncharacterized protein.	0.799

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