84 items (Trypanosoma brucei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tb11.02.2970	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (566 aa)
	Tb11.02.4260	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (986 aa)
	Tb11.01.0330	Protein kinase, putative; Belongs to the protein kinase superfamily. (309 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (554 aa)
	Tb11.01.0850	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (669 aa)
	Tb11.01.2530	Kinesin-like protein, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (617 aa)
	Tb11.01.2695	Delta tubulin; Belongs to the tubulin family. (489 aa)
	Tb11.01.2930	Uncharacterized protein. (992 aa)
	Tb11.01.3150	Spindle pole body component. (799 aa)
	Tb11.01.3720	Uncharacterized protein. (489 aa)
	Tb11.01.3730	Uncharacterized protein. (875 aa)
	Tb11.01.3990	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (916 aa)
	Tb10.6k15.3980	GCP_N_terminal domain-containing protein. (1727 aa)
	KATNA1-2	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (680 aa)
	Tb10.70.6990	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1798 aa)
	Tb10.70.7180	TPR_REGION domain-containing protein. (1756 aa)
	Tb10.70.7260	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2889 aa)
	Tb10.70.7300	WD_REPEATS_REGION domain-containing protein. (1502 aa)
	Tb09.244.2560	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (681 aa)
	Tb09.211.2080	BBS1 domain-containing protein. (609 aa)
	Tb09.211.1500	Katanin, putative. (538 aa)
	Tb09.211.1400	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (482 aa)
	Tb09.160.2260	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (691 aa)
	EB1	End-binding protein 1. (536 aa)
	Tb09.160.0570	Protein kinase, putative. (650 aa)
	Tb10.70.6950	Epsilon tubulin; Belongs to the tubulin family. (487 aa)
	TB927.1.2340	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	TB927.1.2330	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
	TB927.1.1350	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (886 aa)
	TB927.1.1150	Zeta tubulin; Belongs to the tubulin family. (480 aa)
	TB927.1.990	Enkurin domain-containing protein. (374 aa)
	Tb927.8.6830	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1819 aa)
	Tb927.7.3830	Kinesin K39, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1803 aa)
	Tb927.7.4110	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (894 aa)
	Tb927.8.4950	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1456 aa)
	Tb927.8.4840	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1014 aa)
	Tb927.8.4600	RING-type domain-containing protein. (345 aa)
	Tb927.3.3400	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (578 aa)
	Tb927.3.3390	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (591 aa)
	Tb927.7.6290	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (891 aa)
	Tb927.8.2890	Uncharacterized protein. (422 aa)
	Tb927.3.3920	Serine/threonine-protein kinase, putative; Belongs to the protein kinase superfamily. (380 aa)
	Tb927.8.8350	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (768 aa)
	Tb927.7.4830	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (516 aa)
	Tb927.8.2630	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (750 aa)
	Tb927.7.7120	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (810 aa)
	Tb927.7.7260	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1041 aa)
	Tb927.3.1400	Alpha-tubulin N-acetyltransferase; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynam [...] (334 aa)
	Tb927.4.3910	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (787 aa)
	Tb927.7.3000	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1342 aa)
	Tb927.3.2040	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1072 aa)
	Tb927.3.2020	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (746 aa)
	Tb927.7.5040	Uncharacterized protein. (624 aa)
	Tb927.5.2090	OSM3-like kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1088 aa)
	Tb927.3.5490	Uncharacterized protein. (675 aa)
	Tb927.5.2410	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1339 aa)
	Tb927.7.5650	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (638 aa)
	Tb927.3.4960	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1594 aa)
	Tb927.3.2490	PH domain-containing protein. (963 aa)
	Tb927.6.2880	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1085 aa)
	Tb927.4.2640	Uncharacterized protein. (1274 aa)
	Tb927.6.2400	Spindle pole body component. (669 aa)
	Tb927.6.1770	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (628 aa)
	Tb927.6.4390	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1111 aa)
	Tb10.61.1750	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (820 aa)
	Tb10.61.1020	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1095 aa)
	Tb10.61.0990	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1682 aa)
	Tb11.02.0090	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1572 aa)
	Tb11.02.0400	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (862 aa)
	Tb10.61.2930	Tubulin-specific chaperone, putative. (232 aa)
	Tb10.389.1210	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1132 aa)
	Tb10.389.1270	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (832 aa)
	Tb11.01.4703	Uncharacterized protein. (241 aa)
	Tb11.01.5490	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1115 aa)
	Tb11.01.5770	CLASP_N domain-containing protein. (965 aa)
	Tb11.01.8570	Dynein light intermediate chain, putative. (418 aa)
	Tb927.7.3840	Kinesin-like protein, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (53 aa)
	Tb927.4.2730	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (803 aa)
	Tb927.3.910	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (447 aa)
	Tb10.6k15.0540	Spindle pole body component. (784 aa)
	Tb10.6k15.0180	Uncharacterized protein. (822 aa)
	Tb11.02.0790	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (719 aa)
	Tb11.02.2260	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (690 aa)
	Tb11.02.2490	Enkurin domain-containing protein. (274 aa)

Your Current Organism:

Trypanosoma brucei

NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EB1	TB927.1.1150	Q38FP4	Q4GZA3	End-binding protein 1.	Zeta tubulin; Belongs to the tubulin family.	0.716
EB1	TB927.1.2330	Q38FP4	Q4GYY6	End-binding protein 1.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.716
EB1	TB927.1.2340	Q38FP4	Q4GYY5	End-binding protein 1.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.915
EB1	Tb09.160.0570	Q38FP4	Q38FY2	End-binding protein 1.	Protein kinase, putative.	0.503
EB1	Tb10.70.6950	Q38FP4	Q4FKF8	End-binding protein 1.	Epsilon tubulin; Belongs to the tubulin family.	0.716
EB1	Tb11.01.0330	Q38FP4	Q384J7	End-binding protein 1.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.503
EB1	Tb11.01.4703	Q38FP4	Q382M1	End-binding protein 1.	Uncharacterized protein.	0.404
EB1	Tb11.01.5770	Q38FP4	Q382B9	End-binding protein 1.	CLASP_N domain-containing protein.	0.504
EB1	Tb11.02.4260	Q38FP4	Q385C9	End-binding protein 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.404
EB1	Tb927.3.2490	Q38FP4	Q582W2	End-binding protein 1.	PH domain-containing protein.	0.404
EB1	Tb927.3.3920	Q38FP4	Q57WC8	End-binding protein 1.	Serine/threonine-protein kinase, putative; Belongs to the protein kinase superfamily.	0.503
EB1	Tb927.6.2880	Q38FP4	Q583P6	End-binding protein 1.	Kinesin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.404
EB1	Tb927.7.5040	Q38FP4	Q57ZI5	End-binding protein 1.	Uncharacterized protein.	0.404
EB1	Tb927.8.4600	Q38FP4	Q57UZ1	End-binding protein 1.	RING-type domain-containing protein.	0.404
KATNA1	Tb09.211.1500	Q384I4	Q38E06	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Katanin, putative.	0.714
KATNA1	Tb10.70.7300	Q384I4	Q38CF5	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	WD_REPEATS_REGION domain-containing protein.	0.714
KATNA1-2	Tb09.211.1500	Q38CB9	Q38E06	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	Katanin, putative.	0.714
KATNA1-2	Tb10.70.7300	Q38CB9	Q38CF5	Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.	WD_REPEATS_REGION domain-containing protein.	0.714
TB927.1.1150	EB1	Q4GZA3	Q38FP4	Zeta tubulin; Belongs to the tubulin family.	End-binding protein 1.	0.716
TB927.1.1150	TB927.1.2340	Q4GZA3	Q4GYY5	Zeta tubulin; Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.964

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