STRINGSTRING
Tb11.02.5700 Tb11.02.5700 Tb10.70.2140 Tb10.70.2140 Tb10.70.0610 Tb10.70.0610 Tb10.6k15.3220 Tb10.6k15.3220 FEN1 FEN1 Tb927.7.4670 Tb927.7.4670 Tb927.7.4900 Tb927.7.4900 Tb927.3.1920 Tb927.3.1920 PIF5 PIF5 Tb927.4.1630 Tb927.4.1630 Tb927.5.2140 Tb927.5.2140 Tb927.4.1990 Tb927.4.1990 Tb927.6.670 Tb927.6.670 Tb927.6.600 Tb927.6.600 Tb927.4.2430 Tb927.4.2430 Tb10.70.6450 Tb10.70.6450 Tb09.211.3670 Tb09.211.3670 Tb09.160.5280 Tb09.160.5280 Tb09.160.5160 Tb09.160.5160 TB927.1.4220 TB927.1.4220 TbEAP1 TbEAP1 Tb927.5.3850 Tb927.5.3850 Tb927.4.410 Tb927.4.410 Tb927.7.1710 Tb927.7.1710 Tb927.8.2810 Tb927.8.2810 Tb927.7.1170 Tb927.7.1170 Tb10.70.2470 Tb10.70.2470 Tb927.5.4030 Tb927.5.4030 Tb927.2.2180 Tb927.2.2180 Tb11.01.8320 Tb11.01.8320 Tb11.01.5540 Tb11.01.5540 LSM4 LSM4 Tb11.01.2820 Tb11.01.2820 Tb11.01.0260 Tb11.01.0260 Tb10.6k15.3210 Tb10.6k15.3210 Tb11.02.5380 Tb11.02.5380 Tb11.02.4270 Tb11.02.4270 Tb11.55.0025 Tb11.55.0025 Tb10.6k15.0270 Tb10.6k15.0270
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tb11.02.5700Endonuclease/exonuclease/phosphatase, putative. (547 aa)
Tb10.70.2140Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (326 aa)
Tb10.70.06105'-3' exoribonuclease XRND, putative. (801 aa)
Tb10.6k15.3220ATP-dependent DEAD/H RNA helicase, putative. (950 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (393 aa)
Tb927.7.4670Ribosomal RNA processing protein 4. (324 aa)
Tb927.7.49005'-3' exonuclease XRNA, putative. (1418 aa)
Tb927.3.1920Uncharacterized protein. (604 aa)
PIF5ATP-dependent DNA helicase PIF5; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of mitochondrial (kinetoplast) genome stability. Involved in processing of minicircle Okazaki fragments. (928 aa)
Tb927.4.1630Ribosomal RNA processing protein 6. (736 aa)
Tb927.5.2140Regulator of nonsense transcripts 1, putative. (842 aa)
Tb927.4.1990RNA helicase, putative. (626 aa)
Tb927.6.670Ribosomal RNA processing protein 45. (363 aa)
Tb927.6.600CCR4 associated factor, putative. (351 aa)
Tb927.4.2430Endo/exonuclease/phosphatase domain-containing protein. (654 aa)
Tb10.70.6450NOT1. (2326 aa)
Tb09.211.3670CCHC-type domain-containing protein. (390 aa)
Tb09.160.5280Mitochondrial exoribonuclease DSS-1. (743 aa)
Tb09.160.5160Exosome complex exonuclease RRP40. (304 aa)
TB927.1.4220RNase_H2-Ydr279 domain-containing protein. (428 aa)
TbEAP1RNasePH-like protein exosome-associated protein 1 Rrp42 homologue. (397 aa)
Tb927.5.3850XRN_N domain-containing protein. (891 aa)
Tb927.4.410Cell differentiation protein, putative. (316 aa)
Tb927.7.1710Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (405 aa)
Tb927.8.28105'-3' exonuclease XRNC, putative. (868 aa)
Tb927.7.1170RRM domain-containing protein. (159 aa)
Tb10.70.2470Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (477 aa)
Tb927.5.4030U6 snRNA-associated Sm-like protein LSm7p. (92 aa)
Tb927.2.2180Ribosomal RNA processing protein 41B. (256 aa)
Tb11.01.8320Exosome-associated protein 2. (294 aa)
Tb11.01.5540Pab1p-dependent poly(A) ribonuclease subunit, putative. (512 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (127 aa)
Tb11.01.2820Exosome-associated protein 4. (227 aa)
Tb11.01.0260Exosome complex exonuclease RRP44, putative; Belongs to the RNR ribonuclease family. (895 aa)
Tb10.6k15.3210Exosome complex exonuclease RRP41A. (252 aa)
Tb11.02.5380Exosome complex exonuclease RRP44p homologue; Belongs to the RNR ribonuclease family. (972 aa)
Tb11.02.4270Uncharacterized protein. (1454 aa)
Tb11.55.0025XRN_N domain-containing protein. (524 aa)
Tb10.6k15.0270Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (226 aa)
Your Current Organism:
Trypanosoma brucei
NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927
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