(20 nodes) ATP-dependent RNA helicase DEAD-box, conserved site network (Trypanosoma brucei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tb927.8.1080	Centrin, putative. (196 aa)
	Tb11.01.7100	RNA helicase. (725 aa)
	Tb11.01.0610	Mitochondrial DEAD box protein; Belongs to the DEAD box helicase family. (546 aa)
	Tb11.12.0011	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (401 aa)
	Tb10.61.2130	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (660 aa)
	Tb10.406.0540	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (520 aa)
	Tb10.6k15.0530	ATP-dependent DEAD/H RNA helicase, putative. (878 aa)
	Tb10.70.0140	ATP-dependent DEAD/H RNA helicase HEL64, putative; Belongs to the DEAD box helicase family. (568 aa)
	Tb10.70.0540	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (512 aa)
	Tb10.70.3290	ATP-dependent DEAD-box RNA helicase, putative; Belongs to the DEAD box helicase family. (406 aa)
	Tb09.211.3510	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (735 aa)
	Tb09.211.2300	RNA helicase. (795 aa)
	Tb09.160.3270	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (404 aa)
	Tb927.7.7300	ATP-dependent DEAD/H RNA helicase, putative. (1016 aa)
	Tb927.5.3600	ATP-dependent DEAD/H RNA helicase, putative. (948 aa)
	Tb927.3.620	RNA helicase. (808 aa)
	Tb927.5.4270	RNA helicase. (828 aa)
	Tb927.8.1510	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (569 aa)
	Tb927.8.3830	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family. (745 aa)
	Tb927.4.2630	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (843 aa)

Your Current Organism:

Trypanosoma brucei

NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Tb09.160.3270	Tb09.211.3510	Q38F76	Q38DF6	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	0.534
Tb09.160.3270	Tb10.61.2130	Q38F76	Q388E8	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	0.525
Tb09.160.3270	Tb11.12.0011	Q38F76	Q384F2	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	0.798
Tb09.211.2300	Tb10.406.0540	Q38DS7	Q389T9	RNA helicase.	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	0.589
Tb09.211.2300	Tb10.6k15.0530	Q38DS7	Q389Z8	RNA helicase.	ATP-dependent DEAD/H RNA helicase, putative.	0.637
Tb09.211.2300	Tb10.70.0540	Q38DS7	Q38AX7	RNA helicase.	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	0.711
Tb09.211.2300	Tb11.01.0610	Q38DS7	Q384E1	RNA helicase.	Mitochondrial DEAD box protein; Belongs to the DEAD box helicase family.	0.417
Tb09.211.2300	Tb11.01.7100	Q38DS7	Q381N9	RNA helicase.	RNA helicase.	0.520
Tb09.211.2300	Tb927.3.620	Q38DS7	Q57WU5	RNA helicase.	RNA helicase.	0.612
Tb09.211.2300	Tb927.4.2630	Q38DS7	Q584C4	RNA helicase.	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.	0.634
Tb09.211.2300	Tb927.5.4270	Q38DS7	Q57Z22	RNA helicase.	RNA helicase.	0.589
Tb09.211.3510	Tb09.160.3270	Q38DF6	Q38F76	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).	0.534
Tb09.211.3510	Tb10.70.0140	Q38DF6	Q38AU3	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	ATP-dependent DEAD/H RNA helicase HEL64, putative; Belongs to the DEAD box helicase family.	0.447
Tb09.211.3510	Tb10.70.3290	Q38DF6	Q38BK1	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	ATP-dependent DEAD-box RNA helicase, putative; Belongs to the DEAD box helicase family.	0.684
Tb09.211.3510	Tb11.01.0610	Q38DF6	Q384E1	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	Mitochondrial DEAD box protein; Belongs to the DEAD box helicase family.	0.454
Tb09.211.3510	Tb927.3.620	Q38DF6	Q57WU5	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	RNA helicase.	0.473
Tb09.211.3510	Tb927.8.1510	Q38DF6	Q580H2	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	0.529
Tb09.211.3510	Tb927.8.3830	Q38DF6	Q581A3	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	0.481
Tb10.406.0540	Tb09.211.2300	Q389T9	Q38DS7	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	RNA helicase.	0.589
Tb10.406.0540	Tb10.6k15.0530	Q389T9	Q389Z8	ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.	ATP-dependent DEAD/H RNA helicase, putative.	0.481

page 1 of 9

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About