STRINGSTRING
Tb10.70.5200 Tb10.70.5200 Tb927.2.5210 Tb927.2.5210 Tb10.70.5110 Tb10.70.5110 Tb10.70.5120 Tb10.70.5120 Tb09.244.2620 Tb09.244.2620 Tb09.211.4600 Tb09.211.4600 Tb09.211.4570 Tb09.211.4570 Tb09.211.3180 Tb09.211.3180 Tb09.211.1370 Tb09.211.1370 Tb09.160.5260 Tb09.160.5260 Tb09.160.4310 Tb09.160.4310 Tb927.8.6640 Tb927.8.6640 Tb927.7.7410 Tb927.7.7410 Tb927.5.1210 Tb927.5.1210 Tb927.7.3670 Tb927.7.3670 Tb927.7.1600 Tb927.7.1600 Tb927.3.970 Tb927.3.970 Tb927.7.4440 Tb927.7.4440 Tb927.7.4950 Tb927.7.4950 Tb927.7.2440 Tb927.7.2440 Tb927.8.670 Tb927.8.670 Tb927.8.6410 Tb927.8.6410 Tb927.8.6420 Tb927.8.6420 Tb927.8.3530 Tb927.8.3530 Tb927.8.3970 Tb927.8.3970 Tb927.4.1540 Tb927.4.1540 Tb927.8.2210 Tb927.8.2210 Tb927.3.4990 Tb927.3.4990 Tb927.3.4740 Tb927.3.4740 Tb927.3.2230 Tb927.3.2230 Tb927.6.2790 Tb927.6.2790 Tb927.6.1570 Tb927.6.1570 Tb11.01.3040 Tb11.01.3040 Tb11.01.5560 Tb11.01.5560 Tb10.70.3240 Tb10.70.3240 Tb10.6k15.3880 Tb10.6k15.3880 Tb10.6k15.3850 Tb10.6k15.3850 Tb10.6k15.3600 Tb10.6k15.3600 Tb10.6k15.0820 Tb10.6k15.0820 Tb10.389.1850 Tb10.389.1850 Tb10.389.1500 Tb10.389.1500 Tb10.05.0070 Tb10.05.0070 Tb10.61.0980 Tb10.61.0980 Tb10.61.0880 Tb10.61.0880 Tb11.02.0330 Tb11.02.0330 Tb11.02.0990 Tb11.02.0990 Tb11.02.3120 Tb11.02.3120 Tb11.02.3130 Tb11.02.3130 Tb11.02.5650 Tb11.02.5650 Tb11.01.1350 Tb11.01.1350 Tb11.01.1780 Tb11.01.1780 Tb927.6.4300 Tb927.6.4300 Tb927.6.4280 Tb927.6.4280 Tb927.2.4130 Tb927.2.4130 Tb927.2.4520 Tb927.2.4520
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tb10.70.5200Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (558 aa)
Tb927.2.52103-oxoacyl-(Acyl-carrier protein) reductase, putative. (241 aa)
Tb10.70.5110Malate dehydrogenase. (318 aa)
Tb10.70.5120Malate dehydrogenase, putative; Belongs to the LDH/MDH superfamily. (357 aa)
Tb09.244.2620Uncharacterized protein. (373 aa)
Tb09.211.4600Short-chain dehydrogenase, putative. (463 aa)
Tb09.211.4570Short-chain dehydrogenase, putative. (426 aa)
Tb09.211.31806-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
Tb09.211.1370Glyceraldehyde-3-phosphate dehydrogenase, putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (355 aa)
Tb09.160.5260Oxidoreductase, putative. (445 aa)
Tb09.160.4310NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (992 aa)
Tb927.8.6640Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (604 aa)
Tb927.7.7410Oxidoreductase, putative. (335 aa)
Tb927.5.1210Short-chain dehydrogenase, putative. (311 aa)
Tb927.7.3670RCK N-terminal domain-containing protein. (653 aa)
Tb927.7.1600C-1-tetrahydrofolate synthase, cytoplasmic, putative. (298 aa)
Tb927.3.970Uncharacterized protein. (370 aa)
Tb927.7.4440Epimerase domain-containing protein. (292 aa)
Tb927.7.4950NAD(P)-dependent steroid dehydrogenase-like protein. (404 aa)
Tb927.7.2440Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (444 aa)
Tb927.8.670Uncharacterized protein. (290 aa)
Tb927.8.6410Short-chain dehydrogenase, putative. (474 aa)
Tb927.8.6420Short-chain dehydrogenase, putative. (498 aa)
Tb927.8.3530Glycerol-3-phosphate dehydrogenase [NAD(+)]. (354 aa)
Tb927.8.3970Oxidoreductase, putative. (433 aa)
Tb927.4.1540Epimerase domain-containing protein. (508 aa)
Tb927.8.2210Pteridine reductase, putative. (369 aa)
Tb927.3.4990Oxidoreductase, putative. (339 aa)
Tb927.3.4740NAD_Gly3P_dh_N domain-containing protein. (424 aa)
Tb927.3.2230Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
Tb927.6.2790L-threonine 3-dehydrogenase, putative. (332 aa)
Tb927.6.15702-hydroxy-3-oxopropionate reductase, putative. (300 aa)
Tb11.01.3040Malate dehydrogenase. (328 aa)
Tb11.01.5560GDP-L-fucose synthetase, putative. (358 aa)
Tb10.70.3240Short-chain dehydrogenase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa)
Tb10.6k15.3880Short-chain dehydrogenase, putative. (365 aa)
Tb10.6k15.3850Glyceraldehyde-3-phosphate dehydrogenase. (331 aa)
Tb10.6k15.3600Myo-inositol-1-phosphate synthase, putative. (528 aa)
Tb10.6k15.0820Oxidoreductase, putative. (334 aa)
Tb10.389.1850NAD or NADP dependent oxidoreductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
Tb10.389.1500Short-chain dehydrogenase, putative. (327 aa)
Tb10.05.00703Beta_HSD domain-containing protein. (485 aa)
Tb10.61.0980Glycosomal malate dehydrogenase; Belongs to the LDH/MDH superfamily. (323 aa)
Tb10.61.0880GDP-mannose 4,6 dehydratase, putative. (362 aa)
Tb11.02.0330UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (395 aa)
Tb11.02.0990Uncharacterized protein. (1017 aa)
Tb11.02.3120Malic enzyme. (564 aa)
Tb11.02.3130Malic enzyme. (571 aa)
Tb11.02.5650Oxidoreductase-like protein. (859 aa)
Tb11.01.1350Adenosylhomocysteinase. (437 aa)
Tb11.01.1780Short-chain dehydrogenase, putative. (313 aa)
Tb927.6.4300Glyceraldehyde-3-phosphate dehydrogenase. (402 aa)
Tb927.6.4280Glyceraldehyde-3-phosphate dehydrogenase. (402 aa)
Tb927.2.4130Enoyl-CoA hydratase/Enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase, putative. (803 aa)
Tb927.2.4520Uncharacterized protein. (1254 aa)
Your Current Organism:
Trypanosoma brucei
NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927
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