43 items (Trypanosoma brucei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tb11.01.2695	Delta tubulin; Belongs to the tubulin family. (489 aa)
	Tb11.01.2590	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (294 aa)
	Tb11.01.0600	CEP76-C2 domain-containing protein. (632 aa)
	Tb11.02.4440	Aminopeptidase, putative. (521 aa)
	Tb11.02.4320	Uncharacterized protein. (954 aa)
	Tb11.02.4280	Uncharacterized protein. (1319 aa)
	Tb11.02.0070	Aminopeptidase, putative. (565 aa)
	Tb11.03.0750	Uncharacterized protein. (184 aa)
	Tb10.61.2720	Uncharacterized protein. (195 aa)
	Tb927.2.2430	Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. (372 aa)
	Tb10.406.0600	Structural maintenance of chromosomes protein. (1175 aa)
	Tb10.6k15.0540	Spindle pole body component. (784 aa)
	Tb10.6k15.3980	GCP_N_terminal domain-containing protein. (1727 aa)
	Tb10.70.0870	SCD domain-containing protein. (1164 aa)
	Tb10.70.7470	Structural maintenance of chromosomes protein. (1366 aa)
	Tb09.211.4890	Casein kinase II, putative. (349 aa)
	Tb09.211.4130	CS domain-containing protein. (338 aa)
	Tb09.211.2970	Structural maintenance of chromosomes protein. (1275 aa)
	Tb09.160.3470	Condensin subunit 1, putative. (1258 aa)
	Tb10.70.6950	Epsilon tubulin; Belongs to the tubulin family. (487 aa)
	TB927.1.2340	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	TB927.1.2330	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
	TB927.1.1150	Zeta tubulin; Belongs to the tubulin family. (480 aa)
	Tb927.8.8040	Diadenosine tetraphosphatase, putative. (252 aa)
	Tb927.5.3510	Structural maintenance of chromosomes protein. (1199 aa)
	Tb927.7.4290	CS domain-containing protein. (297 aa)
	Tb927.8.3060	Cytosolic leucyl aminopeptidase, putative. (671 aa)
	Tb927.7.6900	Double-strand-break repair protein rad21 homolog, putative. (584 aa)
	Tb927.3.1240	Serine/threonine-protein phosphatase. (323 aa)
	Tb927.4.4330	Serine/threonine protein phosphatase, putative. (250 aa)
	Tb927.7.5090	Uncharacterized protein. (954 aa)
	Tb927.3.3110	Cnd3 domain-containing protein. (1061 aa)
	Tb927.3.5160	Uncharacterized protein. (1232 aa)
	Tb927.4.1710	Rhodanese domain-containing protein. (247 aa)
	Tb927.4.1870	Serine/threonine-protein phosphatase. (426 aa)
	Tb927.6.3090	Uncharacterized protein. (1621 aa)
	Tb927.6.640	Serine/threonine protein phosphatase, putative. (734 aa)
	Tb927.6.2400	Spindle pole body component. (669 aa)
	Tb927.6.2130	Nuclear movement protein, putative. (175 aa)
	Tb927.4.3380	Myosin IB heavy chain, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1167 aa)
	Tb927.3.910	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (447 aa)
	Tb11.01.5770	CLASP_N domain-containing protein. (965 aa)
	Tb11.01.3150	Spindle pole body component. (799 aa)

Your Current Organism:

Trypanosoma brucei

NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TB927.1.1150	TB927.1.2340	Q4GZA3	Q4GYY5	Zeta tubulin; Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.964
TB927.1.1150	Tb11.01.2695	Q4GZA3	Q383I6	Zeta tubulin; Belongs to the tubulin family.	Delta tubulin; Belongs to the tubulin family.	0.590
TB927.1.1150	Tb11.02.4320	Q4GZA3	Q385C3	Zeta tubulin; Belongs to the tubulin family.	Uncharacterized protein.	0.421
TB927.1.1150	Tb927.6.3090	Q4GZA3	Q583M5	Zeta tubulin; Belongs to the tubulin family.	Uncharacterized protein.	0.750
TB927.1.1150	Tb927.7.6900	Q4GZA3	Q57XR0	Zeta tubulin; Belongs to the tubulin family.	Double-strand-break repair protein rad21 homolog, putative.	0.421
TB927.1.2330	TB927.1.2340	Q4GYY6	Q4GYY5	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.997
TB927.1.2330	Tb11.01.2695	Q4GYY6	Q383I6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Delta tubulin; Belongs to the tubulin family.	0.413
TB927.1.2330	Tb11.02.4320	Q4GYY6	Q385C3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.421
TB927.1.2330	Tb927.6.3090	Q4GYY6	Q583M5	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.750
TB927.1.2330	Tb927.7.6900	Q4GYY6	Q57XR0	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Double-strand-break repair protein rad21 homolog, putative.	0.421
TB927.1.2340	TB927.1.1150	Q4GYY5	Q4GZA3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Zeta tubulin; Belongs to the tubulin family.	0.964
TB927.1.2340	TB927.1.2330	Q4GYY5	Q4GYY6	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.997
TB927.1.2340	Tb10.6k15.0540	Q4GYY5	Q389Z9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Spindle pole body component.	0.455
TB927.1.2340	Tb10.70.6950	Q4GYY5	Q4FKF8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Epsilon tubulin; Belongs to the tubulin family.	0.961
TB927.1.2340	Tb927.6.3090	Q4GYY5	Q583M5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.951
Tb09.160.3470	Tb09.211.2970	Q38F58	Q38DK9	Condensin subunit 1, putative.	Structural maintenance of chromosomes protein.	0.936
Tb09.160.3470	Tb09.211.4890	Q38F58	Q38D21	Condensin subunit 1, putative.	Casein kinase II, putative.	0.632
Tb09.160.3470	Tb10.406.0600	Q38F58	Q389U3	Condensin subunit 1, putative.	Structural maintenance of chromosomes protein.	0.999
Tb09.160.3470	Tb10.70.7470	Q38F58	Q38CG6	Condensin subunit 1, putative.	Structural maintenance of chromosomes protein.	0.999
Tb09.160.3470	Tb927.2.2430	Q38F58	Q586L5	Condensin subunit 1, putative.	Casein kinase II, alpha chain; Belongs to the protein kinase superfamily.	0.632

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