STRINGSTRING
Tb09.160.3270 Tb09.160.3270 TB927.1.2330 TB927.1.2330 Tb927.7.710 Tb927.7.710 Tb927.3.2900 Tb927.3.2900 Tb11.01.1370 Tb11.01.1370 Tb11.18.0004 Tb11.18.0004 Tb11.03.0530 Tb11.03.0530 Tb10.61.0210 Tb10.61.0210 Tb10.70.3290 Tb10.70.3290 Tb09.211.0930 Tb09.211.0930 Tb11.01.3110 Tb11.01.3110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tb09.160.3270Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (404 aa)
TB927.1.2330Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
Tb927.7.710Heat shock 70 kDa protein, putative; Belongs to the heat shock protein 70 family. (639 aa)
Tb927.3.2900Elongation initiation factor 2 alpha subunit, putative. (418 aa)
Tb11.01.1370Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (342 aa)
Tb11.18.0004Eukaryotic translation initiation factor 4E, putative; Belongs to the eukaryotic initiation factor 4E family. (233 aa)
Tb11.03.0530Uncharacterized protein. (280 aa)
Tb10.61.0210Eukaryotic translation initiation factor 4E, putative; Belongs to the eukaryotic initiation factor 4E family. (251 aa)
Tb10.70.3290ATP-dependent DEAD-box RNA helicase, putative; Belongs to the DEAD box helicase family. (406 aa)
Tb09.211.0930Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (566 aa)
Tb11.01.3110Heat shock protein 70; Belongs to the heat shock protein 70 family. (690 aa)
Your Current Organism:
Trypanosoma brucei
NCBI taxonomy Id: 185431
Other names: T. brucei brucei TREU927, Trypanosoma brucei TREU927, Trypanosoma brucei brucei TREU927, Trypanosoma brucei brucei strain 927/4 GUTat10.1, Trypanosoma brucei strain TREU927
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