STRINGSTRING
SFN11730.1 SFN11730.1 gmd-3 gmd-3 SFN81479.1 SFN81479.1 SFN75408.1 SFN75408.1 gmd-2 gmd-2 proA proA asd-2 asd-2 SFN46620.1 SFN46620.1 SFN45776.1 SFN45776.1 SFN43245.1 SFN43245.1 SFN39138.1 SFN39138.1 SFN31000.1 SFN31000.1 SFN30751.1 SFN30751.1 SFN30741.1 SFN30741.1 SFN24205.1 SFN24205.1 aroE-4 aroE-4 aroE-3 aroE-3 SFN21744.1 SFN21744.1 asd asd SFN15300.1 SFN15300.1 SFN12069.1 SFN12069.1 SFN06715.1 SFN06715.1 dxr dxr SFM95394.1 SFM95394.1 SFM95032.1 SFM95032.1 SFM94820.1 SFM94820.1 SFM96563.1 SFM96563.1 SFM96382.1 SFM96382.1 SFM91982.1 SFM91982.1 aroE-2 aroE-2 SFM90630.1 SFM90630.1 SFM90369.1 SFM90369.1 SFM89892.1 SFM89892.1 SFM87884.1 SFM87884.1 SFM81482.1 SFM81482.1 SFM79902.1 SFM79902.1 SFM79344.1 SFM79344.1 zwf zwf SFM67519.1 SFM67519.1 SFM66934.1 SFM66934.1 nadX nadX SFM64085.1 SFM64085.1 ilvC ilvC SFM63407.1 SFM63407.1 SFM56297.1 SFM56297.1 SFM48904.1 SFM48904.1 SFM55036.1 SFM55036.1 SFM53425.1 SFM53425.1 SFM53409.1 SFM53409.1 SFM53296.1 SFM53296.1 SFM51791.1 SFM51791.1 SFM51555.1 SFM51555.1 aroE aroE SFM39041.1 SFM39041.1 dapB dapB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SFN11730.13-hydroxyisobutyrate dehydrogenase. (285 aa)
gmd-3GDPmannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (361 aa)
SFN81479.13-hydroxyisobutyrate dehydrogenase. (275 aa)
SFN75408.13-hydroxyisobutyrate dehydrogenase. (293 aa)
gmd-2GDPmannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (361 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (431 aa)
asd-2Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
SFN46620.1Thioredoxin reductase (NADPH). (342 aa)
SFN45776.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (488 aa)
SFN43245.13-hydroxyisobutyrate dehydrogenase. (302 aa)
SFN39138.1Thioredoxin reductase (NADPH). (321 aa)
SFN31000.13-hydroxyisobutyrate dehydrogenase. (297 aa)
SFN30751.1Multimeric flavodoxin WrbA. (358 aa)
SFN30741.1Thioredoxin reductase (NADPH). (299 aa)
SFN24205.13-hydroxyisobutyrate dehydrogenase. (305 aa)
aroE-4Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (275 aa)
aroE-3Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa)
SFN21744.1Thioredoxin reductase. (336 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
SFN15300.1Homoserine dehydrogenase. (438 aa)
SFN12069.1NAD(P)H-dependent nitrite reductase catalytic subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (611 aa)
SFN06715.1Multimeric flavodoxin WrbA. (184 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (422 aa)
SFM95394.1precorrin-3B synthase. (387 aa)
SFM95032.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (478 aa)
SFM94820.13-hydroxyisobutyrate dehydrogenase. (300 aa)
SFM96563.12-hydroxy-3-oxopropionate reductase. (295 aa)
SFM96382.14-hydroxyacetophenone monooxygenase. (636 aa)
SFM91982.1Cyclohexanone monooxygenase/acetone monooxygenase. (546 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa)
SFM90630.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (587 aa)
SFM90369.1Hypothetical protein. (296 aa)
SFM89892.1Predicted homoserine dehydrogenase, contains C-terminal SAF domain. (437 aa)
SFM87884.1NAD(P)H dehydrogenase (quinone). (199 aa)
SFM81482.1NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (465 aa)
SFM79902.1Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
SFM79344.1Sulfite reductase (NADPH) hemoprotein beta-component. (551 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (503 aa)
SFM67519.16-phosphogluconate dehydrogenase (decarboxylating). (332 aa)
SFM66934.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (496 aa)
nadXAspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (274 aa)
SFM64085.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (170 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
SFM63407.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (895 aa)
SFM56297.12-hydroxy-3-oxopropionate reductase. (299 aa)
SFM48904.13-hydroxyisobutyrate dehydrogenase. (339 aa)
SFM55036.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)
SFM53425.1Shikimate dehydrogenase. (268 aa)
SFM53409.1Cyclohexanone monooxygenase. (619 aa)
SFM53296.1Hypothetical protein. (304 aa)
SFM51791.1NADPH-glutathione reductase; Maintains high levels of reduced glutathione. (462 aa)
SFM51555.13-hydroxyisobutyrate dehydrogenase. (290 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (292 aa)
SFM39041.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (500 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (271 aa)
Your Current Organism:
Bradyrhizobium sp. Rc3b
NCBI taxonomy Id: 1855322
Other names: B. sp. Rc3b
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.