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| | gndA | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (473 aa) |
| | glkA | Glucokinase. (298 aa) |
| | LuPra_00430 | Putative FAD-linked oxidoreductase. (530 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa) |
| | gcd_1 | Quinoprotein glucose dehydrogenase. (673 aa) |
| | maeA_1 | NAD-dependent malic enzyme. (532 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (304 aa) |
| | ldhA | D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa) |
| | mak_1 | Fructokinase. (334 aa) |
| | gcd_2 | Quinoprotein glucose dehydrogenase. (715 aa) |
| | gnl | Gluconolactonase. (341 aa) |
| | LuPra_01838 | Putative FAD-linked oxidoreductase. (481 aa) |
| | pgl_1 | 6-phosphogluconolactonase. (404 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa) |
| | maeA_2 | Putative NAD-dependent malic enzyme 2. (557 aa) |
| | yihX_1 | Alpha-D-glucose-1-phosphate phosphatase YihX. (217 aa) |
| | pgl_2 | 6-phosphogluconolactonase. (430 aa) |
| | pflA | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (281 aa) |
| | pflB | Formate acetyltransferase. (752 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | pta | Phosphate acetyltransferase. (314 aa) |
| | LuPra_02355 | Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein. (274 aa) |
| | acdA_1 | Acyl-CoA dehydrogenase. (384 aa) |
| | LuPra_02357 | Uncharacterized protein. (149 aa) |
| | mdh_1 | NAD-dependent methanol dehydrogenase. (426 aa) |
| | gcvT_1 | Aminomethyltransferase; Belongs to the GcvT family. (395 aa) |
| | aceB | Malate synthase A. (634 aa) |
| | fixJ | Transcriptional regulatory protein FixJ. (223 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (562 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa) |
| | pgl_3 | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (252 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (845 aa) |
| | aarA | Citrate synthase; Belongs to the citrate synthase family. (427 aa) |
| | bbsF | Succinyl-CoA:(R)-benzylsuccinate CoA-transferase subunit BbsF; Belongs to the CoA-transferase III family. (398 aa) |
| | ppdK | Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (954 aa) |
| | rpiB | Ribose-5-phosphate isomerase B. (215 aa) |
| | deoC2 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (294 aa) |
| | mmgB | Putative 3-hydroxybutyryl-CoA dehydrogenase. (282 aa) |
| | thlA_1 | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (460 aa) |
| | gcvT_2 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (371 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa) |
| | gcvP | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (956 aa) |
| | adhE | Aldehyde-alcohol dehydrogenase. (602 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa) |
| | odhA | 2-oxoglutarate dehydrogenase E1 component. (932 aa) |
| | odhB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (424 aa) |
| | acyP | Acylphosphatase. (89 aa) |
| | thlA_2 | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa) |
| | scoB | Putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit B. (225 aa) |
| | scoA | Putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit A. (230 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa) |
| | acdA_2 | Acyl-CoA dehydrogenase. (405 aa) |
| | pfp | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (485 aa) |
| | pcaF | Beta-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa) |
| | fadB | Fatty acid oxidation complex subunit alpha. (715 aa) |
| | nifJ | Pyruvate-flavodoxin oxidoreductase. (1187 aa) |
| | korB | 2-oxoglutarate oxidoreductase subunit KorB. (348 aa) |
| | korA | 2-oxoglutarate oxidoreductase subunit KorA. (630 aa) |
| | mdh_2 | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa) |
| | icd_1 | Isocitrate dehydrogenase [NADP]. (415 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (308 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (460 aa) |
| | accB | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa) |
| | pfkA1 | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (361 aa) |
| | LuPra_04310 | Methylmalonyl-CoA carboxyltransferase 12S subunit. (535 aa) |
| | paaF_1 | 2,3-dehydroadipyl-CoA hydratase. (264 aa) |
| | accA1_1 | Acetyl-/propionyl-coenzyme A carboxylase alpha chain. (512 aa) |
| | gcdC_1 | Glutaconyl-CoA decarboxylase subunit gamma. (132 aa) |
| | yngG | Hydroxymethylglutaryl-CoA lyase YngG. (314 aa) |
| | gcd_3 | Quinoprotein glucose dehydrogenase. (725 aa) |
| | etfA | Electron transfer flavoprotein large subunit. (317 aa) |
| | etfB | Electron transfer flavoprotein small subunit. (256 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (399 aa) |
| | echA8 | Putative enoyl-CoA hydratase echA8. (260 aa) |
| | acdA_3 | Acyl-CoA dehydrogenase. (379 aa) |
| | LuPra_04508 | N-acetyltransferase domain-containing protein. (275 aa) |
| | mmgC | Acyl-CoA dehydrogenase. (379 aa) |
| | LuPra_04510 | AP-4-A phosphorylase. (167 aa) |
| | hupA | DNA-binding protein HU 1; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (111 aa) |
| | gno_6 | Gluconate 5-dehydrogenase. (269 aa) |
| | acn | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (899 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (304 aa) |
| | lpdA | Dihydrolipoyl dehydrogenase. (472 aa) |
| | aceF | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (572 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (891 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | gap1 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | tdh_3 | L-threonine 3-dehydrogenase. (350 aa) |
| | cfiB | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1170 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa) |
| | tal_2 | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa) |
| | tktB | Transketolase 2. (622 aa) |
| | icd_2 | Isocitrate dehydrogenase [NADP]. (337 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (324 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa) |
| | ywlF | Sugar phosphate isomerase YwlF. (165 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) |
| | citZ | Citrate synthase; Belongs to the citrate synthase family. (377 aa) |
| | bfmBAB | 2-oxoisovalerate dehydrogenase subunit beta. (708 aa) |
| | paaF_2 | 2,3-dehydroadipyl-CoA hydratase. (256 aa) |
| | fadN | Putative 3-hydroxyacyl-CoA dehydrogenase. (770 aa) |
| | fadA | Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | fadE | Putative acyl-CoA dehydrogenase. (592 aa) |
| | fbaB | Fructose-bisphosphate aldolase class 1. (357 aa) |
| | mdh_3 | Malate dehydrogenase. (270 aa) |
| | lipB | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (216 aa) |
| | pdhC | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (441 aa) |
| | lpdG | Dihydrolipoyl dehydrogenase. (475 aa) |
