STRINGSTRING
cysNC cysNC metX_1 metX_1 mtnC mtnC mtnD mtnD LuPra_00123 LuPra_00123 xecA1 xecA1 LuPra_00328 LuPra_00328 ywrD_1 ywrD_1 ggt_1 ggt_1 LuPra_00414 LuPra_00414 ywrD_2 ywrD_2 acsA acsA LuPra_00561 LuPra_00561 ble_1 ble_1 LuPra_00686 LuPra_00686 LuPra_00783 LuPra_00783 LuPra_00833 LuPra_00833 LuPra_00863 LuPra_00863 gabT gabT LuPra_00921 LuPra_00921 ggt_2 ggt_2 LuPra_01174 LuPra_01174 LuPra_01210 LuPra_01210 LuPra_01457 LuPra_01457 LuPra_01913 LuPra_01913 LuPra_01983 LuPra_01983 cysK1 cysK1 sir sir cysD cysD cysH cysH ackA ackA cysM cysM metE_1 metE_1 LuPra_02370 LuPra_02370 ggt_3 ggt_3 thiL thiL metX_2 metX_2 LuPra_02944 LuPra_02944 LuPra_02966 LuPra_02966 LuPra_03266 LuPra_03266 LuPra_03457 LuPra_03457 LuPra_03458 LuPra_03458 accA accA metH metH metE_2 metE_2 LuPra_04089 LuPra_04089 mshB mshB LuPra_04131 LuPra_04131 folD folD thiE thiE tenI tenI accA1_1 accA1_1 mtnP mtnP metK metK lipA lipA mtnA mtnA thiS thiS thiG thiG LuPra_05323 LuPra_05323 LuPra_05387 LuPra_05387 yitJ_2 yitJ_2 asd2 asd2 thiD thiD accD accD thiC thiC LuPra_05981 LuPra_05981 LuPra_06105 LuPra_06105 LuPra_06195 LuPra_06195
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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cysNCSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (426 aa)
metX_1Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (354 aa)
mtnCEnolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (247 aa)
mtnDAcireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (188 aa)
LuPra_00123Putative enzyme related to lactoylglutathione lyase. (136 aa)
xecA12-hydroxypropyl-CoM lyase. (344 aa)
LuPra_003283-dmu-9_3-mt domain-containing protein. (139 aa)
ywrD_1Gamma-glutamyltransferase YwrD. (616 aa)
ggt_1Gamma-glutamyltranspeptidase. (612 aa)
LuPra_00414Bacillithiol biosynthesis deacetylase BshB1. (296 aa)
ywrD_2Gamma-glutamyltransferase YwrD. (570 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
LuPra_00561Argininosuccinate lyase. (402 aa)
ble_1Phleomycin resistance protein. (124 aa)
LuPra_00686Putative enzyme related to lactoylglutathione lyase. (159 aa)
LuPra_00783Bacillithiol biosynthesis deacetylase BshB1. (329 aa)
LuPra_00833Putative enzyme related to lactoylglutathione lyase. (134 aa)
LuPra_00863Putative enzyme related to lactoylglutathione lyase. (136 aa)
gabT4-aminobutyrate aminotransferase GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
LuPra_00921Uncharacterized protein. (68 aa)
ggt_2Gamma-glutamyltranspeptidase. (597 aa)
LuPra_01174Bacillithiol biosynthesis deacetylase BshB1. (234 aa)
LuPra_01210Methylthioribose kinase. (337 aa)
LuPra_01457Bacillithiol biosynthesis deacetylase BshB1. (266 aa)
LuPra_019133-demethylubiquinone-9 3-methyltransferase. (139 aa)
LuPra_01983Glyoxalase-like domain protein. (313 aa)
cysK1O-acetylserine sulfhydrylase. (67 aa)
sirSulfite reductase [ferredoxin]; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (561 aa)
cysDSulfate adenylyltransferase. (302 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (233 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
cysMCysteine synthase B. (313 aa)
metE_15-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. (381 aa)
LuPra_02370Putative lactoylglutathione lyase. (133 aa)
ggt_3Gamma-glutamyltranspeptidase. (188 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (390 aa)
metX_2Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (342 aa)
LuPra_02944Mycothiol conjugate amidase Mca. (887 aa)
LuPra_02966Argininosuccinate lyase. (423 aa)
LuPra_03266Argininosuccinate lyase. (400 aa)
LuPra_03457Bacillithiol biosynthesis deacetylase BshB1. (297 aa)
LuPra_03458Bacillithiol biosynthesis deacetylase BshB1. (300 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa)
metHMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1228 aa)
metE_25-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. (367 aa)
LuPra_04089Glyoxalase-like domain protein. (81 aa)
mshB1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase. (270 aa)
LuPra_04131Bacillithiol biosynthesis deacetylase BshB1. (287 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (308 aa)
thiEThiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (217 aa)
tenIRegulatory protein TenI. (222 aa)
accA1_1Acetyl-/propionyl-coenzyme A carboxylase alpha chain. (512 aa)
mtnPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (287 aa)
metKS-adenosylmethionine synthase; Belongs to the AdoMet synthase family. (369 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (304 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (365 aa)
thiSThiamine biosynthesis protein ThiS. (66 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (261 aa)
LuPra_05323VOC domain-containing protein. (191 aa)
LuPra_05387Bacillithiol biosynthesis deacetylase BshB1. (289 aa)
yitJ_2Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. (314 aa)
asd2Aspartate-semialdehyde dehydrogenase 2; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa)
thiDHydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (267 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (577 aa)
LuPra_059815'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. (190 aa)
LuPra_06105Mycothiol conjugate amidase Mca. (894 aa)
LuPra_061958-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. (393 aa)
Your Current Organism:
Luteitalea pratensis
NCBI taxonomy Id: 1855912
Other names: Acidobacteria bacterium DSM 100886, Acidobacteria bacterium HEG_-6_39, DSM 100886, KCTC 52215, L. pratensis, Luteitalea pratensis Vieira et al. 2017, strain HEG_-6_39
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