node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LuPra_06195 | glyA | LuPra_06195 | LuPra_05864 | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.933 |
LuPra_06195 | ltaA_1 | LuPra_06195 | LuPra_05446 | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | L-allo-threonine aldolase. | 0.917 |
LuPra_06195 | pucG | LuPra_06195 | LuPra_02136 | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | Purine catabolism protein PucG. | 0.919 |
alaA_1 | pucG | LuPra_00476 | LuPra_02136 | Glutamate-pyruvate aminotransferase AlaA. | Purine catabolism protein PucG. | 0.927 |
cefD_3 | lysN_1 | LuPra_01104 | LuPra_01103 | Isopenicillin N epimerase. | 2-aminoadipate transaminase. | 0.491 |
glyA | LuPra_06195 | LuPra_05864 | LuPra_06195 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | 0.933 |
glyA | ltaA_1 | LuPra_05864 | LuPra_05446 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-allo-threonine aldolase. | 0.924 |
glyA | pucG | LuPra_05864 | LuPra_02136 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Purine catabolism protein PucG. | 0.935 |
hisC_1 | hisC_2 | LuPra_05625 | LuPra_06090 | Histidinol-phosphate aminotransferase. | Histidinol-phosphate aminotransferase. | 0.929 |
hisC_1 | pat | LuPra_05625 | LuPra_00314 | Histidinol-phosphate aminotransferase. | Phenylalanine aminotransferase. | 0.913 |
hisC_2 | hisC_1 | LuPra_06090 | LuPra_05625 | Histidinol-phosphate aminotransferase. | Histidinol-phosphate aminotransferase. | 0.929 |
hisC_2 | pat | LuPra_06090 | LuPra_00314 | Histidinol-phosphate aminotransferase. | Phenylalanine aminotransferase. | 0.929 |
ltaA_1 | LuPra_06195 | LuPra_05446 | LuPra_06195 | L-allo-threonine aldolase. | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | 0.917 |
ltaA_1 | glyA | LuPra_05446 | LuPra_05864 | L-allo-threonine aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
ltaA_1 | pucG | LuPra_05446 | LuPra_02136 | L-allo-threonine aldolase. | Purine catabolism protein PucG. | 0.922 |
lysN_1 | cefD_3 | LuPra_01103 | LuPra_01104 | 2-aminoadipate transaminase. | Isopenicillin N epimerase. | 0.491 |
pat | hisC_1 | LuPra_00314 | LuPra_05625 | Phenylalanine aminotransferase. | Histidinol-phosphate aminotransferase. | 0.913 |
pat | hisC_2 | LuPra_00314 | LuPra_06090 | Phenylalanine aminotransferase. | Histidinol-phosphate aminotransferase. | 0.929 |
pucG | LuPra_06195 | LuPra_02136 | LuPra_06195 | Purine catabolism protein PucG. | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | 0.919 |
pucG | alaA_1 | LuPra_02136 | LuPra_00476 | Purine catabolism protein PucG. | Glutamate-pyruvate aminotransferase AlaA. | 0.927 |