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leuA leuA LuPra_00430 LuPra_00430 acsA acsA blh_1 blh_1 maeA_1 maeA_1 ldhA ldhA LuPra_01838 LuPra_01838 pckG pckG maeA_2 maeA_2 pflB pflB ackA ackA pta pta aceB aceB ppc ppc ppdK ppdK thlA_1 thlA_1 adhE adhE accA accA acyP acyP thlA_2 thlA_2 frdA_1 frdA_1 frdB_2 frdB_2 frdC frdC frdD frdD nifJ nifJ korB korB korA korA mdh_2 mdh_2 accC accC accB accB lpdA lpdA aceF aceF aceE aceE cfiB cfiB fumC fumC accA1_2 accA1_2 pyk pyk accD accD blh_3 blh_3 mdh_3 mdh_3 lpdG lpdG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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leuA2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (399 aa)
LuPra_00430Putative FAD-linked oxidoreductase. (530 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
blh_1Beta-lactamase hydrolase-like protein. (472 aa)
maeA_1NAD-dependent malic enzyme. (532 aa)
ldhAD-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa)
LuPra_01838Putative FAD-linked oxidoreductase. (481 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
maeA_2Putative NAD-dependent malic enzyme 2. (557 aa)
pflBFormate acetyltransferase. (752 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
ptaPhosphate acetyltransferase. (314 aa)
aceBMalate synthase A. (634 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (845 aa)
ppdKPyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (954 aa)
thlA_1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (460 aa)
adhEAldehyde-alcohol dehydrogenase. (602 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa)
acyPAcylphosphatase. (89 aa)
thlA_2Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
frdA_1Fumarate reductase flavoprotein subunit. (599 aa)
frdB_2Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (246 aa)
frdCFumarate reductase 15 kDa hydrophobic protein. (138 aa)
frdDFumarate reductase 13 kDa hydrophobic protein. (117 aa)
nifJPyruvate-flavodoxin oxidoreductase. (1187 aa)
korB2-oxoglutarate oxidoreductase subunit KorB. (348 aa)
korA2-oxoglutarate oxidoreductase subunit KorA. (630 aa)
mdh_2Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (460 aa)
accBBiotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa)
lpdADihydrolipoyl dehydrogenase. (472 aa)
aceFAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (572 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (891 aa)
cfiBPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1170 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
accA1_2Acetyl-/propionyl-coenzyme A carboxylase alpha chain. (509 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa)
blh_3Beta-lactamase hydrolase-like protein. (208 aa)
mdh_3Malate dehydrogenase. (270 aa)
lpdGDihydrolipoyl dehydrogenase. (475 aa)
Your Current Organism:
Luteitalea pratensis
NCBI taxonomy Id: 1855912
Other names: Acidobacteria bacterium DSM 100886, Acidobacteria bacterium HEG_-6_39, DSM 100886, KCTC 52215, L. pratensis, Luteitalea pratensis Vieira et al. 2017, strain HEG_-6_39
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