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acsA acsA LuPra_00624 LuPra_00624 cbbZP cbbZP fdhA_1 fdhA_1 fdhA_2 fdhA_2 fdnH fdnH katE katE LuPra_01453 LuPra_01453 mutB mutB lutA_1 lutA_1 LuPra_02133 LuPra_02133 LuPra_02134 LuPra_02134 pucG pucG gcvT_1 gcvT_1 aceB aceB kdgA kdgA hyi_1 hyi_1 aarA aarA kynB_2 kynB_2 gph_1 gph_1 thlA_1 thlA_1 gcvT_2 gcvT_2 gcvH gcvH gcvP gcvP glnA_1 glnA_1 LuPra_03701 LuPra_03701 thlA_2 thlA_2 mdh_2 mdh_2 ttuD ttuD scpA_2 scpA_2 scpA_3 scpA_3 acn acn lpdA lpdA ttuC ttuC hyi_2 hyi_2 accD5 accD5 amiF amiF LuPra_05807 LuPra_05807 glyA glyA citZ citZ mdh_3 mdh_3 lpdG lpdG dapA_3 dapA_3 glnA_2 glnA_2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
LuPra_006242-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa)
cbbZPPhosphoglycolate phosphatase, plasmid. (217 aa)
fdhA_1Formate dehydrogenase subunit alpha. (260 aa)
fdhA_2Formate dehydrogenase subunit alpha; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (815 aa)
fdnHFormate dehydrogenase-N subunit beta. (730 aa)
katECatalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (792 aa)
LuPra_01453Methylmalonyl-CoA epimerase. (155 aa)
mutBMethylmalonyl-CoA mutase large subunit. (1012 aa)
lutA_1Lactate utilization protein A. (406 aa)
LuPra_02133Putative FAD-linked oxidoreductase. (358 aa)
LuPra_02134Putative FAD-linked oxidoreductase. (481 aa)
pucGPurine catabolism protein PucG. (363 aa)
gcvT_1Aminomethyltransferase; Belongs to the GcvT family. (395 aa)
aceBMalate synthase A. (634 aa)
kdgAKHG/KDPG aldolase. (216 aa)
hyi_1Hydroxypyruvate isomerase. (285 aa)
aarACitrate synthase; Belongs to the citrate synthase family. (427 aa)
kynB_2Kynurenine formamidase. (224 aa)
gph_1Phosphoglycolate phosphatase. (190 aa)
thlA_1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (460 aa)
gcvT_2Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (371 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (956 aa)
glnA_1Glutamine synthetase; Belongs to the glutamine synthetase family. (725 aa)
LuPra_03701Putative FAD-linked oxidoreductase. (470 aa)
thlA_2Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
mdh_2Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa)
ttuDHydroxypyruvate reductase. (442 aa)
scpA_2Methylmalonyl-CoA mutase. (137 aa)
scpA_3Methylmalonyl-CoA mutase. (534 aa)
acnAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (899 aa)
lpdADihydrolipoyl dehydrogenase. (472 aa)
ttuCPutative tartrate dehydrogenase/decarboxylase TtuC. (352 aa)
hyi_2Hydroxypyruvate isomerase; Belongs to the hyi family. (302 aa)
accD5Putative propionyl-CoA carboxylase beta chain 5. (516 aa)
amiFFormamidase. (333 aa)
LuPra_05807Phosphoglycolate phosphatase. (236 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa)
citZCitrate synthase; Belongs to the citrate synthase family. (377 aa)
mdh_3Malate dehydrogenase. (270 aa)
lpdGDihydrolipoyl dehydrogenase. (475 aa)
dapA_34-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (312 aa)
glnA_2Glutamine synthetase. (470 aa)
Your Current Organism:
Luteitalea pratensis
NCBI taxonomy Id: 1855912
Other names: Acidobacteria bacterium DSM 100886, Acidobacteria bacterium HEG_-6_39, DSM 100886, KCTC 52215, L. pratensis, Luteitalea pratensis Vieira et al. 2017, strain HEG_-6_39
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