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preA_1 preA_1 LuPra_00914 LuPra_00914 LuPra_00915 LuPra_00915 acpH acpH coaA coaA ilvC ilvC ilvH ilvH ilvB ilvB ilvD_2 ilvD_2 dat_1 dat_1 coaD coaD coaBC coaBC coaE coaE mazG mazG psf-1 psf-1 ilvK ilvK LuPra_06050 LuPra_06050
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
preA_1NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. (376 aa)
LuPra_00914N-carbamoyl-D-amino acid hydrolase. (290 aa)
LuPra_00915D-hydantoinase. (458 aa)
acpHAcyl carrier protein phosphodiesterase. (205 aa)
coaAPantothenate kinase. (340 aa)
ilvCKetol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (345 aa)
ilvHAcetolactate synthase small subunit. (184 aa)
ilvBAcetolactate synthase. (569 aa)
ilvD_2Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (574 aa)
dat_1D-alanine aminotransferase. (295 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa)
coaBCCoenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (433 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (208 aa)
mazGNucleoside triphosphate pyrophosphohydrolase. (269 aa)
psf-14'-phosphopantetheinyl transferase psf-1; Belongs to the P-Pant transferase superfamily. (245 aa)
ilvKBranched-chain-amino-acid aminotransferase 2. (360 aa)
LuPra_060502-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (321 aa)
Your Current Organism:
Luteitalea pratensis
NCBI taxonomy Id: 1855912
Other names: Acidobacteria bacterium DSM 100886, Acidobacteria bacterium HEG_-6_39, DSM 100886, KCTC 52215, L. pratensis, Luteitalea pratensis Vieira et al. 2017, strain HEG_-6_39
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