(15 nodes) Citrate cycle (TCA cycle), and Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain network (Pseudomonas sp. TCUHL1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	THL1_2177	2-oxoglutarate dehydrogenase. (943 aa)
	THL1_2178	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (405 aa)
	THL1_2179	Dihydrolipoamide dehydrogenase. (478 aa)
	THL1_2382	Lipoate--protein ligase. (236 aa)
	THL1_2431	Dihydrolipoamide dehydrogenase. (469 aa)
	THL1_2922	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha. (329 aa)
	THL1_2923	Pyruvate dehydrogenase. (341 aa)
	THL1_2924	Biotin attachment protein. (77 aa)
	THL1_2925	Acetoin dehydrogenase. (234 aa)
	THL1_2926	Lipoate--protein ligase. (244 aa)
	THL1_4745	Branched-chain alpha-keto acid dehydrogenase subunit E2. (368 aa)
	THL1_4746	2-oxoisovalerate dehydrogenase. (333 aa)
	pdhA	ABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (363 aa)
	THL1_5278	Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)
	THL1_5279	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (648 aa)

Your Current Organism:

Pseudomonas sp. TCUHL1

NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THL1_2177	THL1_2178	THL1_2177	THL1_2178	2-oxoglutarate dehydrogenase.	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.999
THL1_2177	THL1_2179	THL1_2177	THL1_2179	2-oxoglutarate dehydrogenase.	Dihydrolipoamide dehydrogenase.	0.993
THL1_2177	THL1_2382	THL1_2177	THL1_2382	2-oxoglutarate dehydrogenase.	Lipoate--protein ligase.	0.606
THL1_2177	THL1_2431	THL1_2177	THL1_2431	2-oxoglutarate dehydrogenase.	Dihydrolipoamide dehydrogenase.	0.986
THL1_2177	THL1_2922	THL1_2177	THL1_2922	2-oxoglutarate dehydrogenase.	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha.	0.635
THL1_2177	THL1_2923	THL1_2177	THL1_2923	2-oxoglutarate dehydrogenase.	Pyruvate dehydrogenase.	0.740
THL1_2177	THL1_2924	THL1_2177	THL1_2924	2-oxoglutarate dehydrogenase.	Biotin attachment protein.	0.928
THL1_2177	THL1_2925	THL1_2177	THL1_2925	2-oxoglutarate dehydrogenase.	Acetoin dehydrogenase.	0.946
THL1_2177	THL1_2926	THL1_2177	THL1_2926	2-oxoglutarate dehydrogenase.	Lipoate--protein ligase.	0.606
THL1_2177	THL1_4745	THL1_2177	THL1_4745	2-oxoglutarate dehydrogenase.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.945
THL1_2177	THL1_4746	THL1_2177	THL1_4746	2-oxoglutarate dehydrogenase.	2-oxoisovalerate dehydrogenase.	0.740
THL1_2177	THL1_5278	THL1_2177	THL1_5278	2-oxoglutarate dehydrogenase.	Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.577
THL1_2177	THL1_5279	THL1_2177	THL1_5279	2-oxoglutarate dehydrogenase.	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.947
THL1_2177	pdhA	THL1_2177	THL1_4747	2-oxoglutarate dehydrogenase.	ABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.622
THL1_2178	THL1_2177	THL1_2178	THL1_2177	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	2-oxoglutarate dehydrogenase.	0.999
THL1_2178	THL1_2179	THL1_2178	THL1_2179	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.997
THL1_2178	THL1_2382	THL1_2178	THL1_2382	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Lipoate--protein ligase.	0.613
THL1_2178	THL1_2431	THL1_2178	THL1_2431	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.994
THL1_2178	THL1_2922	THL1_2178	THL1_2922	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha.	0.947
THL1_2178	THL1_2923	THL1_2178	THL1_2923	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Pyruvate dehydrogenase.	0.963