(10 nodes) 2-oxoacid dehydrogenase acyltransferase, catalytic domain, and Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor network (Pseudomonas sp. TCUHL1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THL1_2177	2-oxoglutarate dehydrogenase. (943 aa)
	THL1_2178	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (405 aa)
	THL1_2179	Dihydrolipoamide dehydrogenase. (478 aa)
	THL1_2431	Dihydrolipoamide dehydrogenase. (469 aa)
	THL1_2925	Acetoin dehydrogenase. (234 aa)
	THL1_4745	Branched-chain alpha-keto acid dehydrogenase subunit E2. (368 aa)
	THL1_4746	2-oxoisovalerate dehydrogenase. (333 aa)
	pdhA	ABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (363 aa)
	THL1_5278	Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)
	THL1_5279	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (648 aa)

Your Current Organism:

Pseudomonas sp. TCUHL1

NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THL1_2177	THL1_2178	THL1_2177	THL1_2178	2-oxoglutarate dehydrogenase.	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.999
THL1_2177	THL1_2179	THL1_2177	THL1_2179	2-oxoglutarate dehydrogenase.	Dihydrolipoamide dehydrogenase.	0.993
THL1_2177	THL1_2431	THL1_2177	THL1_2431	2-oxoglutarate dehydrogenase.	Dihydrolipoamide dehydrogenase.	0.986
THL1_2177	THL1_2925	THL1_2177	THL1_2925	2-oxoglutarate dehydrogenase.	Acetoin dehydrogenase.	0.946
THL1_2177	THL1_4745	THL1_2177	THL1_4745	2-oxoglutarate dehydrogenase.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.945
THL1_2177	THL1_4746	THL1_2177	THL1_4746	2-oxoglutarate dehydrogenase.	2-oxoisovalerate dehydrogenase.	0.740
THL1_2177	THL1_5278	THL1_2177	THL1_5278	2-oxoglutarate dehydrogenase.	Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.577
THL1_2177	THL1_5279	THL1_2177	THL1_5279	2-oxoglutarate dehydrogenase.	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.947
THL1_2177	pdhA	THL1_2177	THL1_4747	2-oxoglutarate dehydrogenase.	ABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.622
THL1_2178	THL1_2177	THL1_2178	THL1_2177	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	2-oxoglutarate dehydrogenase.	0.999
THL1_2178	THL1_2179	THL1_2178	THL1_2179	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.997
THL1_2178	THL1_2431	THL1_2178	THL1_2431	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.994
THL1_2178	THL1_4746	THL1_2178	THL1_4746	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	2-oxoisovalerate dehydrogenase.	0.961
THL1_2178	THL1_5278	THL1_2178	THL1_5278	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.741
THL1_2178	pdhA	THL1_2178	THL1_4747	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	ABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.937
THL1_2179	THL1_2177	THL1_2179	THL1_2177	Dihydrolipoamide dehydrogenase.	2-oxoglutarate dehydrogenase.	0.993
THL1_2179	THL1_2178	THL1_2179	THL1_2178	Dihydrolipoamide dehydrogenase.	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.997
THL1_2179	THL1_2431	THL1_2179	THL1_2431	Dihydrolipoamide dehydrogenase.	Dihydrolipoamide dehydrogenase.	0.905
THL1_2179	THL1_2925	THL1_2179	THL1_2925	Dihydrolipoamide dehydrogenase.	Acetoin dehydrogenase.	0.992
THL1_2179	THL1_4745	THL1_2179	THL1_4745	Dihydrolipoamide dehydrogenase.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.991