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THL1_101 THL1_101 THL1_2172 THL1_2172 THL1_2173 THL1_2173 THL1_2174 THL1_2174 THL1_2175 THL1_2175 THL1_2176 THL1_2176 sucC sucC sucD sucD THL1_2473 THL1_2473 THL1_2474 THL1_2474 THL1_2783 THL1_2783 THL1_2942 THL1_2942 THL1_3656 THL1_3656 THL1_3677 THL1_3677 THL1_3678 THL1_3678 THL1_3679 THL1_3679 prpB prpB THL1_3795 THL1_3795 THL1_4602 THL1_4602
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THL1_101acetyl-CoA hydrolase. (497 aa)
THL1_2172Type II citrate synthase; Belongs to the citrate synthase family. (428 aa)
THL1_2173Succinate dehydrogenase. (124 aa)
THL1_2174Succinate dehydrogenase; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa)
THL1_2175Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
THL1_2176Succinate dehydrogenase. (238 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
THL1_2473Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (742 aa)
THL1_2474Isocitrate dehydrogenase. (418 aa)
THL1_27832-methylcitrate dehydratase. (494 aa)
THL1_29422-methylcitrate dehydratase. (446 aa)
THL1_3656Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (884 aa)
THL1_36773-methylitaconate isomerase. (395 aa)
THL1_3678Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (876 aa)
THL1_3679Methylcitrate synthase; Belongs to the citrate synthase family. (385 aa)
prpB2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (294 aa)
THL1_3795Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (896 aa)
THL1_46022-methylisocitrate lyase. (275 aa)
Your Current Organism:
Pseudomonas sp. TCUHL1
NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1
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