STRINGSTRING
mnmC mnmC THL1_1462 THL1_1462 THL1_1467 THL1_1467 THL1_1468 THL1_1468 THL1_1469 THL1_1469 THL1_1470 THL1_1470 folD folD folD-2 folD-2 THL1_1513 THL1_1513 THL1_1946 THL1_1946 THL1_204 THL1_204 proC proC THL1_2774 THL1_2774 THL1_314 THL1_314 THL1_3254 THL1_3254 THL1_3289 THL1_3289 queF queF THL1_353 THL1_353 THL1_354 THL1_354 folD-3 folD-3 THL1_3737 THL1_3737 THL1_3867 THL1_3867 THL1_393 THL1_393 THL1_394 THL1_394 THL1_395 THL1_395 THL1_396 THL1_396 THL1_4158 THL1_4158 THL1_4410 THL1_4410 THL1_462 THL1_462 THL1_5066 THL1_5066
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mnmCFAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (655 aa)
THL1_1462Flavin reductase. (161 aa)
THL1_1467Sarcosine oxidase. (189 aa)
THL1_1468Aminomethyltransferase; Belongs to the GcvT family. (965 aa)
THL1_1469Sarcosine oxidase subunit delta. (100 aa)
THL1_1470Sarcosine oxidase subunit beta. (413 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (307 aa)
folD-2Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (303 aa)
THL1_1513Flavin reductase. (161 aa)
THL1_1946Transcriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1325 aa)
THL1_204Diacylglycerol kinase; Belongs to the dihydrofolate reductase family. (207 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)
THL1_2774Flavin oxidoreductase. (312 aa)
THL1_3145,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (281 aa)
THL1_3254Flavin reductase. (202 aa)
THL1_3289Hypothetical protein. (79 aa)
queFpreQ1 synthase / 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (277 aa)
THL1_353(Fe-S)-binding protein. (652 aa)
THL1_354N-methylproline demethylase. (686 aa)
folD-3Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
THL1_3737Electron transfer flavoprotein-ubiquinoneoxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (551 aa)
THL1_3867Oxidoreductase. (192 aa)
THL1_393Sarcosine oxidase subunit beta. (416 aa)
THL1_394Sarcosine oxidase subunit delta. (108 aa)
THL1_395Sarcosine oxidase subunit alpha; Belongs to the GcvT family. (1005 aa)
THL1_396Sarcosine oxidase subunit gamma. (209 aa)
THL1_4158Monooxygenase. (170 aa)
THL1_44104-hydroxyphenylacetate 3-monooxygenase reductase component. (168 aa)
THL1_462Flavin reductase. (217 aa)
THL1_50663-beta hydroxysteroid dehydrogenase. (213 aa)
Your Current Organism:
Pseudomonas sp. TCUHL1
NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1
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