(5 nodes) Tricarboxylic acid cycle enzyme complex network (Pseudomonas sp. TCUHL1)

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Your Input:
	THL1_2172	Type II citrate synthase; Belongs to the citrate synthase family. (428 aa)
	sucD	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
	THL1_2177	2-oxoglutarate dehydrogenase. (943 aa)
	fumC	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
	THL1_3679	Methylcitrate synthase; Belongs to the citrate synthase family. (385 aa)

Your Current Organism:

Pseudomonas sp. TCUHL1

NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THL1_2172	THL1_2177	THL1_2172	THL1_2177	Type II citrate synthase; Belongs to the citrate synthase family.	2-oxoglutarate dehydrogenase.	0.858
THL1_2172	fumC	THL1_2172	THL1_1394	Type II citrate synthase; Belongs to the citrate synthase family.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.903
THL1_2172	sucD	THL1_2172	THL1_2181	Type II citrate synthase; Belongs to the citrate synthase family.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.732
THL1_2177	THL1_2172	THL1_2177	THL1_2172	2-oxoglutarate dehydrogenase.	Type II citrate synthase; Belongs to the citrate synthase family.	0.858
THL1_2177	THL1_3679	THL1_2177	THL1_3679	2-oxoglutarate dehydrogenase.	Methylcitrate synthase; Belongs to the citrate synthase family.	0.769
THL1_2177	fumC	THL1_2177	THL1_1394	2-oxoglutarate dehydrogenase.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.670
THL1_2177	sucD	THL1_2177	THL1_2181	2-oxoglutarate dehydrogenase.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.967
THL1_3679	THL1_2177	THL1_3679	THL1_2177	Methylcitrate synthase; Belongs to the citrate synthase family.	2-oxoglutarate dehydrogenase.	0.769
THL1_3679	fumC	THL1_3679	THL1_1394	Methylcitrate synthase; Belongs to the citrate synthase family.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.537
THL1_3679	sucD	THL1_3679	THL1_2181	Methylcitrate synthase; Belongs to the citrate synthase family.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.695
fumC	THL1_2172	THL1_1394	THL1_2172	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Type II citrate synthase; Belongs to the citrate synthase family.	0.903
fumC	THL1_2177	THL1_1394	THL1_2177	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	2-oxoglutarate dehydrogenase.	0.670
fumC	THL1_3679	THL1_1394	THL1_3679	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Methylcitrate synthase; Belongs to the citrate synthase family.	0.537
fumC	sucD	THL1_1394	THL1_2181	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.831
sucD	THL1_2172	THL1_2181	THL1_2172	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Type II citrate synthase; Belongs to the citrate synthase family.	0.732
sucD	THL1_2177	THL1_2181	THL1_2177	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxoglutarate dehydrogenase.	0.967
sucD	THL1_3679	THL1_2181	THL1_3679	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Methylcitrate synthase; Belongs to the citrate synthase family.	0.695
sucD	fumC	THL1_2181	THL1_1394	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.831