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| | THL1_3223 | isovaleryl-CoA dehydrogenase. (387 aa) |
| | THL1_3227 | hydroxymethylglutaryl-CoA lyase. (301 aa) |
| | THL1_3224 | methylcrotonoyl-CoA carboxylase. (535 aa) |
| | THL1_917 | acyl-CoA thioesterase II. (289 aa) |
| | THL1_876 | Hypothetical protein. (348 aa) |
| | anmK | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (363 aa) |
| | THL1_675 | Zinc-binding protein. (112 aa) |
| | THL1_652 | P-hydroxybenzoate hydroxylase. (395 aa) |
| | THL1_564 | 5-aminovalerate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa) |
| | THL1_5614 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa) |
| | THL1_561 | Protein CsiD. (325 aa) |
| | THL1_5604 | Leucine-responsive regulatory protein. (162 aa) |
| | dadA | Amino acid dehydrogenase; Oxidative deamination of D-amino acids. (432 aa) |
| | THL1_5572 | phenylacetate--CoA ligase. (438 aa) |
| | THL1_5570 | methylcrotonoyl-CoA carboxylase. (535 aa) |
| | THL1_5567 | hydroxymethylglutaryl-CoA lyase. (301 aa) |
| | gcvT | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (360 aa) |
| | gcvH-3 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | gcvP-3 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa) |
| | THL1_5463 | 3-hydroxyacyl-CoA dehydrogenase. (373 aa) |
| | THL1_5462 | acyl-CoA dehydrogenase. (596 aa) |
| | THL1_5460 | Thioesterase. (145 aa) |
| | THL1_1020 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (282 aa) |
| | THL1_110 | glutaryl-CoA dehydrogenase. (393 aa) |
| | THL1_1103 | acyl-CoA dehydrogenase. (379 aa) |
| | THL1_1139 | Glutathione S-transferase. (212 aa) |
| | THL1_1153 | Ornithine cyclodeaminase. (318 aa) |
| | THL1_1154 | FAD-dependent oxidoreductase. (374 aa) |
| | THL1_118 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa) |
| | algL | poly(beta-D-mannuronate) lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism; Belongs to the polysaccharide lyase 5 family. (365 aa) |
| | THL1_1324 | AMP-binding protein. (576 aa) |
| | THL1_1390 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | THL1_1403 | Maleylacetoacetate isomerase. (221 aa) |
| | THL1_1409 | Hypothetical protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (407 aa) |
| | THL1_1413 | enoyl-CoA hydratase. (288 aa) |
| | THL1_1415 | enoyl-CoA hydratase. (252 aa) |
| | THL1_1416 | acyl-CoA dehydrogenase. (388 aa) |
| | THL1_1418 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa) |
| | THL1_1425 | acyl-CoA dehydrogenase. (395 aa) |
| | THL1_1428 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | THL1_1467 | Sarcosine oxidase. (189 aa) |
| | THL1_1468 | Aminomethyltransferase; Belongs to the GcvT family. (965 aa) |
| | THL1_1470 | Sarcosine oxidase subunit beta. (413 aa) |
| | THL1_1500 | Aminomethyltransferase; Belongs to the GcvT family. (781 aa) |
| | THL1_1504 | Aminomethyltransferase; Belongs to the GcvT family. (376 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | THL1_1533 | Aldehyde dehydrogenase. (541 aa) |
| | THL1_1537 | Muconate cycloisomerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (377 aa) |
| | THL1_1549 | Benzene 1,2-dioxygenase. (163 aa) |
| | glaH | Protein CsiD; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (325 aa) |
| | THL1_1566 | 3-amino-2-methylpropionate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa) |
| | THL1_1573 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | THL1_1575 | Amino acid dehydrogenase. (424 aa) |
| | THL1_1675 | Phenylalanine 4-hydroxylase. (263 aa) |
| | THL1_1698 | Zn-dependent hydrolase. (259 aa) |
| | THL1_1801 | acyl-CoA dehydrogenase. (379 aa) |
| | THL1_1858 | Amidohydrolase. (580 aa) |
| | THL1_1876 | Agmatinase; Belongs to the arginase family. (319 aa) |
| | THL1_1899 | Glyoxylate carboligase; Belongs to the TPP enzyme family. (591 aa) |
| | THL1_1944 | acyl-CoA dehydrogenase. (382 aa) |
| | THL1_1946 | Transcriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1325 aa) |
| | THL1_2045 | 2,4-dienoyl-CoA reductase. (678 aa) |
| | THL1_2069 | NAD-glutamate dehydrogenase. (1620 aa) |
| | THL1_210 | Lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (341 aa) |
| | fadB | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa) |
| | fadA | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (391 aa) |
| | THL1_215 | Amino acid dehydrogenase. (413 aa) |
| | THL1_2244 | Agmatinase; Belongs to the arginase family. (317 aa) |
| | THL1_2275 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | THL1_2276 | 3-hydroxyacyl-CoA dehydrogenase. (714 aa) |
| | THL1_5449 | Carbamate kinase; Belongs to the carbamate kinase family. (310 aa) |
| | THL1_5448 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (336 aa) |
| | arcA | Arginine deiminase. (416 aa) |
| | THL1_5354 | N-formimino-L-glutamate deiminase. (454 aa) |
| | THL1_5353 | Histidine utilization repressor. (250 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa) |
| | hutH | Histidine ammonia-lyase. (510 aa) |
| | THL1_5344 | Histidine ammonia-lyase. (510 aa) |
| | hutI | Imidazolonepropionase. (402 aa) |
| | THL1_5342 | N-formylglutamate amidohydrolase. (267 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa) |
| | THL1_5251 | butyryl-CoA dehydrogenase. (425 aa) |
| | THL1_5250 | acyl-CoA dehydrogenase. (401 aa) |
| | THL1_5242 | Oxidoreductase. (651 aa) |
| | speA | Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa) |
| | THL1_5072 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa) |
| | THL1_5026 | Methylmalonate-semialdehyde dehydrogenase. (498 aa) |
| | THL1_5019 | Dioxygenase. (249 aa) |
| | THL1_497 | Alanine racemase. (425 aa) |
| | THL1_4947 | 4Fe-4S ferredoxin. (937 aa) |
| | nbaC | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (190 aa) |
| | THL1_4809 | Glycerol acyltransferase. (387 aa) |
| | THL1_4793 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (414 aa) |
| | THL1_4746 | 2-oxoisovalerate dehydrogenase. (333 aa) |
| | THL1_4676 | enoyl-CoA hydratase. (257 aa) |
| | THL1_456 | Agmatinase; Belongs to the arginase family. (324 aa) |
| | slyX | Hypothetical protein; Belongs to the SlyX family. (68 aa) |
| | THL1_442 | Amine oxidase. (560 aa) |
| | THL1_4407 | 3-ketosteroid 9alpha-hydroxylase component KshB. (352 aa) |
| | THL1_4391 | Aminomethyltransferase. (372 aa) |
| | THL1_439 | phenylacyl-CoA dehydrogenase. (598 aa) |
| | gcvP-2 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa) |
| | gcvH-2 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa) |
| | THL1_4386 | Fis family transcriptional regulator. (511 aa) |
| | THL1_4384 | Arginase; Belongs to the arginase family. (323 aa) |
| | THL1_437 | acyl-CoA dehydrogenase. (601 aa) |
| | THL1_4336 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (294 aa) |
| | THL1_4335 | enoyl-CoA hydratase. (376 aa) |
| | THL1_4334 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa) |
| | THL1_4333 | acyl-CoA dehydrogenase. (387 aa) |
| | THL1_4332 | Methylmalonate-semialdehyde dehydrogenase. (497 aa) |
| | THL1_4297 | Proline:sodium symporter PutP; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (497 aa) |
| | THL1_4288 | Arginine N-succinyltransferase. (338 aa) |
| | THL1_4287 | Arginine N-succinyltransferase subunit beta. (340 aa) |
| | astD | Succinylglutamate-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (487 aa) |
| | astB | N-succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (448 aa) |
| | astE | Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (332 aa) |
| | THL1_4282 | Threonine aldolase. (334 aa) |
| | THL1_4260 | Hypothetical protein. (161 aa) |
| | THL1_4239 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | THL1_4237 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa) |
| | THL1_4236 | 3-hydroxyacyl-CoA dehydrogenase. (504 aa) |
| | THL1_4225 | acyl-CoA dehydrogenase. (383 aa) |
| | THL1_4220 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | THL1_4219 | 3-hydroxyacyl-CoA dehydrogenase. (715 aa) |
| | THL1_419 | Glutathione S-transferase. (207 aa) |
| | THL1_4177 | Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | THL1_4176 | 3-hydroxybutyryl-CoA dehydrogenase. (282 aa) |
| | THL1_4172 | Putidaredoxin reductase. (422 aa) |
| | THL1_4170 | 5-exo-hydroxycamphor dehydrogenase. (361 aa) |
| | THL1_4139 | isobutyryl-CoA dehydrogenase. (383 aa) |
| | THL1_2285 | butyryl-CoA dehydrogenase. (383 aa) |
| | THL1_2286 | 3-hydroxyisobutyryl-CoA hydrolase. (362 aa) |
| | THL1_2287 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (296 aa) |
| | THL1_2288 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_2289 | Methylmalonate-semialdehyde dehydrogenase. (502 aa) |
| | THL1_229 | Alpha/beta hydrolase. (336 aa) |
| | THL1_2316 | enoyl-CoA hydratase. (263 aa) |
| | THL1_2342 | acyl-CoA thioesterase. (265 aa) |
| | THL1_2434 | Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (373 aa) |
| | THL1_2518 | Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | THL1_4138 | 3-hydroxyisobutyryl-CoA hydrolase. (367 aa) |
| | THL1_4137 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (296 aa) |
| | THL1_4136 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_4135 | Methylmalonate-semialdehyde dehydrogenase. (501 aa) |
| | THL1_4104 | FAD-dependent oxidoreductase. (376 aa) |
| | THL1_4092 | Long-chain fatty acid--CoA ligase. (562 aa) |
| | THL1_4091 | Long-chain fatty acid--CoA ligase. (568 aa) |
| | THL1_4088 | Hydrolase. (144 aa) |
| | THL1_4087 | 3-oxoacyl-ACP synthase. (373 aa) |
| | THL1_4069 | Fumarylacetoacetase. (434 aa) |
| | hmgA | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (431 aa) |
| | THL1_4044 | 4-hydroxyphenylpyruvate dioxygenase. (358 aa) |
| | THL1_4042 | Maleylacetoacetate isomerase. (210 aa) |
| | THL1_4003 | Histidine kinase. (748 aa) |
| | THL1_4001 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | THL1_4000 | acyl-CoA dehydrogenase. (386 aa) |
| | THL1_3997 | Aspartate aminotransferase. (396 aa) |
| | THL1_396 | Sarcosine oxidase subunit gamma. (209 aa) |
| | THL1_395 | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. (1005 aa) |
| | THL1_394 | Sarcosine oxidase subunit delta. (108 aa) |
| | THL1_393 | Sarcosine oxidase subunit beta. (416 aa) |
| | THL1_3872 | Amidohydrolase. (575 aa) |
| | THL1_3797 | poly(beta-D-mannuronate) lyase. (363 aa) |
| | THL1_379 | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa) |
| | THL1_3735 | Electron transfer flavoprotein subunit beta. (309 aa) |
| | THL1_3721 | acyl-CoA dehydrogenase. (386 aa) |
| | THL1_3720 | acetyl-CoA carboxylase. (538 aa) |
| | THL1_3677 | 3-methylitaconate isomerase. (395 aa) |
| | THL1_3656 | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (884 aa) |
| | THL1_363 | NADPH:quinone reductase. (294 aa) |
| | THL1_3612 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa) |
| | THL1_3606 | Aminoglycoside phosphotransferase. (356 aa) |
| | THL1_3541 | acyl-CoA dehydrogenase. (379 aa) |
| | THL1_3537 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
| | THL1_3536 | 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa) |
| | THL1_3535 | acyl-CoA dehydrogenase. (398 aa) |
| | THL1_3532 | Electron transfer flavoprotein subunit beta. (309 aa) |
| | THL1_3531 | 3-hydroxybutyryl-CoA dehydrogenase. (506 aa) |
| | THL1_3530 | Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | THL1_3529 | glutaryl-CoA dehydrogenase. (393 aa) |
| | THL1_3523 | Methylmalonate-semialdehyde dehydrogenase. (498 aa) |
| | THL1_351 | Electron transfer flavoprotein subunit alpha. (410 aa) |
| | THL1_3498 | 3-hydroxyacyl-CoA dehydrogenase. (703 aa) |
| | THL1_3496 | Aminoglycoside phosphotransferase. (356 aa) |
| | THL1_3486 | Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | THL1_3481 | Long-chain fatty acid--CoA ligase. (519 aa) |
| | THL1_3480 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa) |
| | THL1_3477 | Amine oxidase. (498 aa) |
| | THL1_3468 | Amine oxidase. (495 aa) |
| | THL1_3460 | phytanoyl-CoA dioxygenase. (277 aa) |
| | THL1_3437 | 4-oxalomesaconate tautomerase. (366 aa) |
| | THL1_3410 | phytanoyl-CoA dioxygenase. (279 aa) |
| | THL1_3354 | Hypothetical protein. (589 aa) |
| | THL1_3349 | Oxidoreductase; Belongs to the LDH2/MDH2 oxidoreductase family. (333 aa) |
| | THL1_3344 | Hypothetical protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (368 aa) |
| | THL1_3331 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (314 aa) |
| | THL1_3323 | Thioesterase. (139 aa) |
| | THL1_3229 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | THL1_2531 | 4-hydroxyphenylpyruvate dioxygenase. (636 aa) |
| | THL1_2606 | Diaminopropionate ammonia-lyase. (429 aa) |
| | THL1_2646 | AMP-binding protein. (647 aa) |
| | THL1_2647 | Fumarylacetoacetate hydrolase. (318 aa) |
| | THL1_2655 | 3-(3-hydroxyphenyl)propionate hydroxylase. (551 aa) |
| | THL1_2715 | Gluconokinase. (173 aa) |
| | THL1_272 | 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (221 aa) |
| | THL1_2742 | Glycolate dehydrogenase. (1015 aa) |
| | THL1_2747 | 2-keto-3-deoxy-L-rhamnonate aldolase; Belongs to the HpcH/HpaI aldolase family. (268 aa) |
| | THL1_2752 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. (257 aa) |
| | THL1_2753 | 4-hydroxyphenylacetate isomerase. (219 aa) |
| | THL1_2788 | Hypothetical protein. (350 aa) |
| | THL1_2791 | (2Fe-2S)-binding protein. (116 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (526 aa) |
| | THL1_2821 | Amidohydrolase. (578 aa) |
| | THL1_2830 | Aminomethyltransferase. (372 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (954 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa) |
| | THL1_2834 | Fis family transcriptional regulator. (507 aa) |
| | ilvA-2 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa) |
| | THL1_2875 | 4-hydroxybenzoate hydroxylase. (394 aa) |
| | THL1_2885 | Protocatechuate 3,4-dioxygenase beta chain. (239 aa) |
| | THL1_2893 | Benzene 1,2-dioxygenase. (162 aa) |
| | THL1_2923 | Pyruvate dehydrogenase. (341 aa) |
| | THL1_2935 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (296 aa) |
| | THL1_2943 | AraC family transcriptional regulator. (346 aa) |
| | THL1_2966 | Demethylmenaquinone methyltransferase. (208 aa) |
| | THL1_2971 | Transcriptional regulator. (159 aa) |
| | THL1_2974 | Arginine N-succinyltransferase. (347 aa) |
| | THL1_308 | Amine oxidase. (491 aa) |
| | THL1_3163 | acyl-CoA dehydrogenase. (409 aa) |
| | THL1_3165 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_3166 | 2-methyl-branched-chain-enoyl-CoA reductase. (375 aa) |
| | THL1_3167 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | THL1_3183 | Phenylacetic acid degradation protein. (307 aa) |
| | THL1_3186 | 2,3-dehydroadipyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_3187 | enoyl-CoA hydratase. (263 aa) |
| | THL1_3188 | 3-hydroxyacyl-CoA dehydrogenase. (505 aa) |
| | THL1_3189 | Phenylacetic acid degradation protein. (149 aa) |
| | THL1_3190 | beta-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | THL1_3191 | phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (436 aa) |
| | THL1_3195 | phenylacetate-CoA oxygenase. (330 aa) |
| | THL1_3196 | phenylacetyl-CoA oxygenase subunit PaaB. (93 aa) |
| | THL1_3197 | Phenylacetic acid degradation protein. (253 aa) |
| | THL1_3198 | phenylacetate-CoA oxygenase. (177 aa) |
| | THL1_3199 | Phenylacetic acid degradation protein. (358 aa) |
| | THL1_3203 | enoyl-CoA hydratase. (686 aa) |
