(59 nodes) Outer membrane-bounded periplasmic space network (Pseudomonas sp. TCUHL1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THL1_199	Ribonuclease T2; Belongs to the RNase T2 family. (332 aa)
	THL1_1999	Transporter. (348 aa)
	THL1_2119	Lytic transglycosylase. (644 aa)
	THL1_222	Gamma-glutamyltransferase. (569 aa)
	THL1_2251	Histidine kinase. (882 aa)
	THL1_2298	Hypothetical protein. (221 aa)
	THL1_232	Peptidase M16. (451 aa)
	THL1_2355	Esterase. (201 aa)
	THL1_2407	MexE family multidrug efflux RND transporter periplasmic adaptor subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (413 aa)
	THL1_2546	Hypothetical protein. (350 aa)
	THL1_2676	Multidrug transporter. (417 aa)
	THL1_2808	Transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (390 aa)
	THL1_2837	Hypothetical protein; Belongs to the peptidase M16 family. (818 aa)
	THL1_2851	Branched-chain amino acid ABC transportersubstrate-binding protein. (398 aa)
	THL1_2941	Glycine/betaine ABC transporter substrate-binding protein. (343 aa)
	THL1_3545	ABC transporter permease. (403 aa)
	THL1_3633	ABC transporter substrate-binding protein. (608 aa)
	THL1_3634	Hypothetical protein. (615 aa)
	THL1_371	Pilus assembly protein. (246 aa)
	THL1_3873	Peptidase C45. (358 aa)
	THL1_3902	Histidine kinase. (450 aa)
	THL1_3926	Thiol--disulfide interchange protein DsbE. (178 aa)
	THL1_3993	Peptide ABC transporter substrate-bindingprotein. (533 aa)
	THL1_4041	Membrane protein. (696 aa)
	THL1_4071	Hypothetical protein. (137 aa)
	THL1_4345	MBL fold metallo-hydrolase. (595 aa)
	THL1_4399	MexA family multidrug efflux RND transporter periplasmic adaptor subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (380 aa)
	cpoB	Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (274 aa)
	THL1_4510	Lipoprotein. (135 aa)
	THL1_4817	Cupin. (157 aa)
	nbaC	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (190 aa)
	THL1_5056	RND-type multidrug efflux pump membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (388 aa)
	THL1_5146	Urea ABC transporter substrate-binding protein UrtA. (421 aa)
	THL1_5208	Membrane protein; HflC and HflK could encode or regulate a protease. (389 aa)
	THL1_5228	Lipoprotein. (237 aa)
	THL1_5386	Peptidase M23. (421 aa)
	THL1_5589	Molecular chaperone. (239 aa)
	THL1_5612	Peptide ABC transporter substrate-bindingprotein. (524 aa)
	THL1_782	Hypothetical protein. (302 aa)
	THL1_792	Hypothetical protein. (700 aa)
	THL1_839	Hypothetical protein. (438 aa)
	mrdA	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (632 aa)
	THL1_849	Lytic transglycosylase. (339 aa)
	THL1_851	D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (387 aa)
	lnt	Acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (506 aa)
	THL1_855	Murein transglycosylase. (436 aa)
	THL1_1045	Peptide ABC transporter substrate-bindingprotein. (533 aa)
	THL1_1048	Peptide ABC transporter substrate-bindingprotein. (528 aa)
	THL1_1049	Peptide ABC transporter substrate-bindingprotein. (533 aa)
	lptC	Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (189 aa)
	THL1_1082	Toluene tolerance protein Ttg2D. (214 aa)
	THL1_1251	Cupin. (106 aa)
	THL1_1316	Murein-DD-endopeptidase; Belongs to the peptidase S11 family. (315 aa)
	THL1_1342	Peptidase S41; Belongs to the peptidase S41A family. (693 aa)
	THL1_1347	Molybdate ABC transporter substrate-binding protein. (251 aa)
	THL1_1547	ABC transporter substrate-binding protein. (387 aa)
	THL1_1745	Hypothetical protein. (777 aa)
	THL1_1792	Histidine kinase. (538 aa)
	THL1_1966	Deoxyribonuclease. (229 aa)

Your Current Organism:

Pseudomonas sp. TCUHL1

NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THL1_1045	THL1_3633	THL1_1045	THL1_3633	Peptide ABC transporter substrate-bindingprotein.	ABC transporter substrate-binding protein.	0.608
THL1_1045	THL1_3634	THL1_1045	THL1_3634	Peptide ABC transporter substrate-bindingprotein.	Hypothetical protein.	0.608
THL1_1045	THL1_3993	THL1_1045	THL1_3993	Peptide ABC transporter substrate-bindingprotein.	Peptide ABC transporter substrate-bindingprotein.	0.476
THL1_1048	THL1_1049	THL1_1048	THL1_1049	Peptide ABC transporter substrate-bindingprotein.	Peptide ABC transporter substrate-bindingprotein.	0.751
THL1_1048	THL1_3633	THL1_1048	THL1_3633	Peptide ABC transporter substrate-bindingprotein.	ABC transporter substrate-binding protein.	0.608
THL1_1048	THL1_3634	THL1_1048	THL1_3634	Peptide ABC transporter substrate-bindingprotein.	Hypothetical protein.	0.608
THL1_1048	THL1_3993	THL1_1048	THL1_3993	Peptide ABC transporter substrate-bindingprotein.	Peptide ABC transporter substrate-bindingprotein.	0.495
THL1_1049	THL1_1048	THL1_1049	THL1_1048	Peptide ABC transporter substrate-bindingprotein.	Peptide ABC transporter substrate-bindingprotein.	0.751
THL1_1049	THL1_3633	THL1_1049	THL1_3633	Peptide ABC transporter substrate-bindingprotein.	ABC transporter substrate-binding protein.	0.608
THL1_1049	THL1_3634	THL1_1049	THL1_3634	Peptide ABC transporter substrate-bindingprotein.	Hypothetical protein.	0.608
THL1_1049	THL1_3993	THL1_1049	THL1_3993	Peptide ABC transporter substrate-bindingprotein.	Peptide ABC transporter substrate-bindingprotein.	0.477
THL1_1082	THL1_839	THL1_1082	THL1_839	Toluene tolerance protein Ttg2D.	Hypothetical protein.	0.511
THL1_1082	lptC	THL1_1082	THL1_1076	Toluene tolerance protein Ttg2D.	Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.	0.784
THL1_1316	mrdA	THL1_1316	THL1_847	Murein-DD-endopeptidase; Belongs to the peptidase S11 family.	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.638
THL1_1342	THL1_5386	THL1_1342	THL1_5386	Peptidase S41; Belongs to the peptidase S41A family.	Peptidase M23.	0.463
THL1_1547	THL1_3545	THL1_1547	THL1_3545	ABC transporter substrate-binding protein.	ABC transporter permease.	0.936
THL1_1547	THL1_5146	THL1_1547	THL1_5146	ABC transporter substrate-binding protein.	Urea ABC transporter substrate-binding protein UrtA.	0.499
THL1_1745	THL1_5228	THL1_1745	THL1_5228	Hypothetical protein.	Lipoprotein.	0.568
THL1_1745	lptC	THL1_1745	THL1_1076	Hypothetical protein.	Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.	0.471
THL1_1999	THL1_2407	THL1_1999	THL1_2407	Transporter.	MexE family multidrug efflux RND transporter periplasmic adaptor subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.590