(18 nodes) ATP-grasp fold network (Pseudomonas sp. TCUHL1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	purK	5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa)
	ddl	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (315 aa)
	sucC	succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
	gshB	Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. (320 aa)
	THL1_3226	3-methylcrotonyl-CoA carboxylase. (647 aa)
	THL1_3684	Hypothetical protein. (328 aa)
	THL1_3723	3-methylcrotonyl-CoA carboxylase. (661 aa)
	THL1_3999	Hypothetical protein. (705 aa)
	THL1_4152	Carbamoyl-phosphate synthase large subunit. (1096 aa)
	THL1_4354	Urea carboxylase. (1217 aa)
	purT	Phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (393 aa)
	carB	Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1073 aa)
	THL1_5133	acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
	purD	Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (429 aa)
	rimK	Ribosomal protein S6 modification protein; Belongs to the RimK family. (301 aa)
	THL1_5568	3-methylcrotonyl-CoA carboxylase subunitalpha. (648 aa)
	THL1_5687	Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (471 aa)
	THL1_781	Carbamoyl-phosphate synthase large subunit. (1089 aa)

Your Current Organism:

Pseudomonas sp. TCUHL1

NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THL1_3226	THL1_4152	THL1_3226	THL1_4152	3-methylcrotonyl-CoA carboxylase.	Carbamoyl-phosphate synthase large subunit.	0.987
THL1_3226	THL1_4354	THL1_3226	THL1_4354	3-methylcrotonyl-CoA carboxylase.	Urea carboxylase.	0.476
THL1_3226	THL1_5133	THL1_3226	THL1_5133	3-methylcrotonyl-CoA carboxylase.	acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.474
THL1_3226	THL1_5568	THL1_3226	THL1_5568	3-methylcrotonyl-CoA carboxylase.	3-methylcrotonyl-CoA carboxylase subunitalpha.	0.900
THL1_3226	THL1_5687	THL1_3226	THL1_5687	3-methylcrotonyl-CoA carboxylase.	Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.462
THL1_3226	THL1_781	THL1_3226	THL1_781	3-methylcrotonyl-CoA carboxylase.	Carbamoyl-phosphate synthase large subunit.	0.987
THL1_3684	ddl	THL1_3684	THL1_1129	Hypothetical protein.	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.	0.472
THL1_3723	THL1_4152	THL1_3723	THL1_4152	3-methylcrotonyl-CoA carboxylase.	Carbamoyl-phosphate synthase large subunit.	0.987
THL1_3723	THL1_4354	THL1_3723	THL1_4354	3-methylcrotonyl-CoA carboxylase.	Urea carboxylase.	0.484
THL1_3723	THL1_5133	THL1_3723	THL1_5133	3-methylcrotonyl-CoA carboxylase.	acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.471
THL1_3723	THL1_5687	THL1_3723	THL1_5687	3-methylcrotonyl-CoA carboxylase.	Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.462
THL1_3723	THL1_781	THL1_3723	THL1_781	3-methylcrotonyl-CoA carboxylase.	Carbamoyl-phosphate synthase large subunit.	0.988
THL1_3999	THL1_5133	THL1_3999	THL1_5133	Hypothetical protein.	acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.901
THL1_3999	THL1_5687	THL1_3999	THL1_5687	Hypothetical protein.	Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.803
THL1_3999	sucC	THL1_3999	THL1_2180	Hypothetical protein.	succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.830
THL1_4152	THL1_3226	THL1_4152	THL1_3226	Carbamoyl-phosphate synthase large subunit.	3-methylcrotonyl-CoA carboxylase.	0.987
THL1_4152	THL1_3723	THL1_4152	THL1_3723	Carbamoyl-phosphate synthase large subunit.	3-methylcrotonyl-CoA carboxylase.	0.987
THL1_4152	THL1_4354	THL1_4152	THL1_4354	Carbamoyl-phosphate synthase large subunit.	Urea carboxylase.	0.763
THL1_4152	THL1_5133	THL1_4152	THL1_5133	Carbamoyl-phosphate synthase large subunit.	acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.761
THL1_4152	THL1_5568	THL1_4152	THL1_5568	Carbamoyl-phosphate synthase large subunit.	3-methylcrotonyl-CoA carboxylase subunitalpha.	0.987