(17 nodes) AMP-binding enzyme, C-terminal domain network (Pseudomonas sp. TCUHL1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THL1_4091	Long-chain fatty acid--CoA ligase. (568 aa)
	THL1_4092	Long-chain fatty acid--CoA ligase. (562 aa)
	THL1_4155	Fatty acid--CoA ligase. (544 aa)
	THL1_4223	acyl-CoA ligase MyrC. (514 aa)
	acsA	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
	THL1_4405	Fatty acid--CoA ligase. (522 aa)
	THL1_4792	Medium-chain fatty-acid--CoA ligase. (560 aa)
	acsA-2	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
	THL1_1324	AMP-binding protein. (576 aa)
	THL1_2290	acetyl-CoA synthetase. (567 aa)
	THL1_2646	AMP-binding protein. (647 aa)
	THL1_3169	AMP-binding protein. (539 aa)
	THL1_3172	AMP-binding protein. (566 aa)
	THL1_3233	Putative acetoacetyl-CoA synthetase. (668 aa)
	THL1_3481	Long-chain fatty acid--CoA ligase. (519 aa)
	THL1_3538	Hypothetical protein. (555 aa)
	THL1_3725	Long-chain acyl-CoA synthetase. (607 aa)

Your Current Organism:

Pseudomonas sp. TCUHL1

NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THL1_1324	THL1_2290	THL1_1324	THL1_2290	AMP-binding protein.	acetyl-CoA synthetase.	0.662
THL1_1324	THL1_3169	THL1_1324	THL1_3169	AMP-binding protein.	AMP-binding protein.	0.664
THL1_1324	THL1_3233	THL1_1324	THL1_3233	AMP-binding protein.	Putative acetoacetyl-CoA synthetase.	0.534
THL1_1324	THL1_4091	THL1_1324	THL1_4091	AMP-binding protein.	Long-chain fatty acid--CoA ligase.	0.561
THL1_1324	acsA	THL1_1324	THL1_4296	AMP-binding protein.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.600
THL1_1324	acsA-2	THL1_1324	THL1_4906	AMP-binding protein.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.602
THL1_2290	THL1_1324	THL1_2290	THL1_1324	acetyl-CoA synthetase.	AMP-binding protein.	0.662
THL1_2290	THL1_2646	THL1_2290	THL1_2646	acetyl-CoA synthetase.	AMP-binding protein.	0.649
THL1_2290	THL1_3169	THL1_2290	THL1_3169	acetyl-CoA synthetase.	AMP-binding protein.	0.921
THL1_2290	THL1_3172	THL1_2290	THL1_3172	acetyl-CoA synthetase.	AMP-binding protein.	0.666
THL1_2290	THL1_3481	THL1_2290	THL1_3481	acetyl-CoA synthetase.	Long-chain fatty acid--CoA ligase.	0.657
THL1_2290	THL1_3538	THL1_2290	THL1_3538	acetyl-CoA synthetase.	Hypothetical protein.	0.660
THL1_2290	THL1_3725	THL1_2290	THL1_3725	acetyl-CoA synthetase.	Long-chain acyl-CoA synthetase.	0.565
THL1_2290	THL1_4091	THL1_2290	THL1_4091	acetyl-CoA synthetase.	Long-chain fatty acid--CoA ligase.	0.629
THL1_2290	THL1_4092	THL1_2290	THL1_4092	acetyl-CoA synthetase.	Long-chain fatty acid--CoA ligase.	0.630
THL1_2290	THL1_4155	THL1_2290	THL1_4155	acetyl-CoA synthetase.	Fatty acid--CoA ligase.	0.667
THL1_2290	THL1_4223	THL1_2290	THL1_4223	acetyl-CoA synthetase.	acyl-CoA ligase MyrC.	0.627
THL1_2290	THL1_4405	THL1_2290	THL1_4405	acetyl-CoA synthetase.	Fatty acid--CoA ligase.	0.654
THL1_2290	THL1_4792	THL1_2290	THL1_4792	acetyl-CoA synthetase.	Medium-chain fatty-acid--CoA ligase.	0.638
THL1_2290	acsA	THL1_2290	THL1_4296	acetyl-CoA synthetase.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.918