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THL1_4725 THL1_4725 rsmC rsmC THL1_4833 THL1_4833 prmC prmC THL1_4908 THL1_4908 rlmE-2 rlmE-2 cmoM cmoM prmA prmA rsmA rsmA rlmJ rlmJ ubiE ubiE THL1_5416 THL1_5416 THL1_5729 THL1_5729 rsmG rsmG THL1_590 THL1_590 THL1_637 THL1_637 THL1_741 THL1_741 THL1_766 THL1_766 THL1_790 THL1_790 THL1_832 THL1_832 THL1_841 THL1_841 trmA trmA rlmG rlmG rsmH rsmH rlmF rlmF THL1_1357 THL1_1357 mnmC mnmC THL1_1401 THL1_1401 THL1_1438 THL1_1438 THL1_1601 THL1_1601 rlmE rlmE THL1_1811 THL1_1811 THL1_19 THL1_19 THL1_1988 THL1_1988 THL1_2013 THL1_2013 rlmL rlmL THL1_217 THL1_217 THL1_230 THL1_230 THL1_2315 THL1_2315 tpm tpm THL1_2379 THL1_2379 trmB trmB THL1_249 THL1_249 THL1_2957 THL1_2957 THL1_302 THL1_302 THL1_320 THL1_320 THL1_3577 THL1_3577 THL1_3628 THL1_3628 speE speE prmB prmB THL1_3763 THL1_3763 rlmM rlmM THL1_3847 THL1_3847 ubiG ubiG THL1_4011 THL1_4011 THL1_4029 THL1_4029 cmoA cmoA cmoB cmoB bioC bioC THL1_4418 THL1_4418 rlmD rlmD pcm pcm THL1_4582 THL1_4582 rsmJ rsmJ THL1_4624 THL1_4624
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THL1_4725Methyltransferase. (231 aa)
rsmC16S rRNA methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (332 aa)
THL1_4833Cyclopropane-fatty-acyl-phospholipid synthase. (423 aa)
prmCSAM-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (276 aa)
THL1_4908SAM-dependent methyltransferase; Belongs to the methyltransferase superfamily. (339 aa)
rlmE-2Hypothetical protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (207 aa)
cmoMSAM-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family. (249 aa)
prmARibosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (292 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (268 aa)
rlmJLactate dehydrogenase; Specifically methylates the adenine in position 2030 of 23S rRNA. (279 aa)
ubiEUbiquinone biosynthesis methyltransferaseUbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (256 aa)
THL1_5416SAM-dependent methyltransferase. (404 aa)
THL1_5729Cyclopropane-fatty-acyl-phospholipid synthase. (396 aa)
rsmGRibosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (215 aa)
THL1_590Hypothetical protein. (504 aa)
THL1_637Type III modification methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family. (292 aa)
THL1_741precorrin-6Y C5,15-methyltransferase. (408 aa)
THL1_766Methyltransferase. (217 aa)
THL1_790Methyltransferase; Belongs to the methyltransferase superfamily. (312 aa)
THL1_832Phospholipid methyltransferase. (203 aa)
THL1_841Polyketide biosynthesis methyltransferase. (281 aa)
trmAtRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (364 aa)
rlmG50S rRNA methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (374 aa)
rsmH16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (315 aa)
rlmF23S rRNA methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (330 aa)
THL1_1357Methyltransferase type 12. (191 aa)
mnmCFAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (655 aa)
THL1_1401Hypothetical protein. (298 aa)
THL1_1438Chemotaxis protein CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (281 aa)
THL1_1601SAM-dependent methyltransferase. (242 aa)
rlmE23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (206 aa)
THL1_1811SAM-dependent methyltransferase. (216 aa)
THL1_19Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (437 aa)
THL1_1988Membrane protein. (673 aa)
THL1_2013SAM-dependent methyltransferase. (254 aa)
rlmL50S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (725 aa)
THL1_217SAM-dependent methyltransferase. (398 aa)
THL1_23016S rRNA methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (205 aa)
THL1_2315Hypothetical protein. (248 aa)
tpmThiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. (233 aa)
THL1_2379SAM-dependent methyltransferase. (249 aa)
trmBtRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (238 aa)
THL1_249Methionine biosynthesis protein MetW. (206 aa)
THL1_2957Cyclopropane-fatty-acyl-phospholipid synthase. (169 aa)
THL1_302Methyltransferase. (295 aa)
THL1_320ArsR family transcriptional regulator. (333 aa)
THL1_3577DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (307 aa)
THL1_3628Hypothetical protein. (254 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (286 aa)
prmBSAM-dependent methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. (304 aa)
THL1_3763Type I restriction-modification protein subunit M. (799 aa)
rlmM23S rRNA methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (349 aa)
THL1_3847Methyltransferase. (209 aa)
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (232 aa)
THL1_4011Chemotaxis protein. (275 aa)
THL1_4029Methyltransferase type 12. (223 aa)
cmoAtRNA methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (247 aa)
cmoBtRNA methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (322 aa)
bioCmalonyl-CoA O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (271 aa)
THL1_4418SAM-dependent methyltransferase. (348 aa)
rlmD23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (450 aa)
pcmprotein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (225 aa)
THL1_4582rRNA methyltransferase. (268 aa)
rsmJSAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. (257 aa)
THL1_4624Methyltransferase. (416 aa)
Your Current Organism:
Pseudomonas sp. TCUHL1
NCBI taxonomy Id: 1856685
Other names: P. sp. TCU-HL1, Pseudomonas sp. TCU-HL1
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