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| | THL1_1413 | enoyl-CoA hydratase. (288 aa) |
| | THL1_1415 | enoyl-CoA hydratase. (252 aa) |
| | THL1_1418 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa) |
| | THL1_1428 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa) |
| | fadB | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa) |
| | THL1_2179 | Dihydrolipoamide dehydrogenase. (478 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa) |
| | THL1_2275 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | THL1_2276 | 3-hydroxyacyl-CoA dehydrogenase. (714 aa) |
| | THL1_2284 | enoyl-CoA hydratase. (229 aa) |
| | THL1_2288 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_2289 | Methylmalonate-semialdehyde dehydrogenase. (502 aa) |
| | THL1_2290 | acetyl-CoA synthetase. (567 aa) |
| | THL1_2316 | enoyl-CoA hydratase. (263 aa) |
| | THL1_2431 | Dihydrolipoamide dehydrogenase. (469 aa) |
| | THL1_2743 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa) |
| | THL1_2783 | 2-methylcitrate dehydratase. (494 aa) |
| | THL1_2900 | Alcohol dehydrogenase. (327 aa) |
| | THL1_3165 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_3166 | 2-methyl-branched-chain-enoyl-CoA reductase. (375 aa) |
| | THL1_3167 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | THL1_3169 | AMP-binding protein. (539 aa) |
| | THL1_3186 | 2,3-dehydroadipyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_3229 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | THL1_3486 | Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | THL1_3523 | Methylmalonate-semialdehyde dehydrogenase. (498 aa) |
| | THL1_3537 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
| | THL1_3612 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa) |
| | THL1_3656 | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (884 aa) |
| | THL1_3677 | 3-methylitaconate isomerase. (395 aa) |
| | THL1_3678 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (876 aa) |
| | THL1_3679 | Methylcitrate synthase; Belongs to the citrate synthase family. (385 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (294 aa) |
| | THL1_3999 | Hypothetical protein. (705 aa) |
| | THL1_4135 | Methylmalonate-semialdehyde dehydrogenase. (501 aa) |
| | THL1_4136 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | THL1_4177 | Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | THL1_4219 | 3-hydroxyacyl-CoA dehydrogenase. (715 aa) |
| | THL1_4220 | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | THL1_4237 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa) |
| | THL1_4239 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | acsA | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa) |
| | THL1_4332 | Methylmalonate-semialdehyde dehydrogenase. (497 aa) |
| | accA | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa) |
| | THL1_457 | CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (518 aa) |
| | THL1_4579 | Aldehyde reductase. (383 aa) |
| | THL1_4596 | Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family. (277 aa) |
| | ackA | Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (388 aa) |
| | THL1_4778 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (677 aa) |
| | THL1_4793 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | acsA-2 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa) |
| | THL1_5026 | Methylmalonate-semialdehyde dehydrogenase. (498 aa) |
| | THL1_5028 | Beta-alanine--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa) |
| | THL1_5072 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa) |
| | THL1_5132 | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa) |
| | THL1_5133 | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | THL1_5608 | Omega amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa) |
