(12 nodes) Amyloid precursor protein catabolic process, and PHTF1/2, N-terminal network (Carlito syrichta)

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second shell of interactors

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proteins of unknown 3D structure

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protein homology

Your Input:
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (679 aa)
	ENSTSYP00000003660	annotation not available (886 aa)
	ADAM17	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1. (824 aa)
	PHTF1	Putative homeodomain transcription factor 1. (601 aa)
	APH1B	Gamma-secretase subunit APH-1B. (245 aa)
	PSENEN	Gamma-secretase subunit PEN-2. (101 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
	NCSTN	Nicastrin isoform X1. (708 aa)
	FAT3	Protocadherin Fat 3. (2319 aa)
	APH1A	Gamma-secretase subunit APH-1A isoform X1. (265 aa)
	LOC103253504	Mucin-4-like. (733 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	ADAM17	ENSTSYP00000002825	ENSTSYP00000008166	Disintegrin and metalloproteinase domain-containing protein 10.	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	0.888
ADAM10	APH1A	ENSTSYP00000002825	ENSTSYP00000030221	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1A isoform X1.	0.551
ADAM10	APH1B	ENSTSYP00000002825	ENSTSYP00000008833	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1B.	0.459
ADAM10	ENSTSYP00000003660	ENSTSYP00000002825	ENSTSYP00000003660	Disintegrin and metalloproteinase domain-containing protein 10.	annotation not available	0.826
ADAM10	FAT3	ENSTSYP00000002825	ENSTSYP00000029894	Disintegrin and metalloproteinase domain-containing protein 10.	Protocadherin Fat 3.	0.826
ADAM10	LOC103253504	ENSTSYP00000002825	ENSTSYP00000031234	Disintegrin and metalloproteinase domain-containing protein 10.	Mucin-4-like.	0.580
ADAM10	NCSTN	ENSTSYP00000002825	ENSTSYP00000023582	Disintegrin and metalloproteinase domain-containing protein 10.	Nicastrin isoform X1.	0.656
ADAM10	PHTF1	ENSTSYP00000002825	ENSTSYP00000008675	Disintegrin and metalloproteinase domain-containing protein 10.	Putative homeodomain transcription factor 1.	0.532
ADAM10	PSEN1	ENSTSYP00000002825	ENSTSYP00000032237	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.613
ADAM10	PSEN2	ENSTSYP00000002825	ENSTSYP00000018767	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.574
ADAM10	PSENEN	ENSTSYP00000002825	ENSTSYP00000014007	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit PEN-2.	0.652
ADAM17	ADAM10	ENSTSYP00000008166	ENSTSYP00000002825	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Disintegrin and metalloproteinase domain-containing protein 10.	0.888
ADAM17	ENSTSYP00000003660	ENSTSYP00000008166	ENSTSYP00000003660	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	annotation not available	0.826
ADAM17	FAT3	ENSTSYP00000008166	ENSTSYP00000029894	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Protocadherin Fat 3.	0.826
ADAM17	LOC103253504	ENSTSYP00000008166	ENSTSYP00000031234	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Mucin-4-like.	0.511
ADAM17	NCSTN	ENSTSYP00000008166	ENSTSYP00000023582	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Nicastrin isoform X1.	0.649
ADAM17	PHTF1	ENSTSYP00000008166	ENSTSYP00000008675	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Putative homeodomain transcription factor 1.	0.691
ADAM17	PSEN1	ENSTSYP00000008166	ENSTSYP00000032237	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.486
ADAM17	PSEN2	ENSTSYP00000008166	ENSTSYP00000018767	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.562
ADAM17	PSENEN	ENSTSYP00000008166	ENSTSYP00000014007	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Gamma-secretase subunit PEN-2.	0.561