STRINGSTRING
MED13L MED13L PLPPR1 PLPPR1 TAF3 TAF3 CDK19 CDK19 MED7 MED7 MED10 MED10 GTF2H1 GTF2H1 MED14 MED14 TAF2 TAF2 TAF12 TAF12 ENSTSYP00000004911 ENSTSYP00000004911 MED22 MED22 MED8 MED8 TBPL1 TBPL1 MED29 MED29 MED13 MED13 CDK8 CDK8 GTF2H3 GTF2H3 TAF5 TAF5 PLPPR5 PLPPR5 MED6 MED6 CDK7 CDK7 LOC103259463 LOC103259463 GTF2H4 GTF2H4 TAF4B TAF4B GTF2B GTF2B CCNH CCNH GTF2F1 GTF2F1 TAF7L TAF7L GTF2E2 GTF2E2 MED12L MED12L FBXW12 FBXW12 MED16 MED16 PLPPR4 PLPPR4 LOC103251355 LOC103251355 MED15 MED15 GTF2E1 GTF2E1 PLPPR2 PLPPR2 MED25 MED25 TAF13 TAF13 ENSTSYP00000017951 ENSTSYP00000017951 ENSTSYP00000018417 ENSTSYP00000018417 GTF2A1L GTF2A1L MED21 MED21 MED24 MED24 MED28 MED28 ERCC3 ERCC3 GTF2H5 GTF2H5 MED9 MED9 ENSTSYP00000021098 ENSTSYP00000021098 TAF1 TAF1 TAF4 TAF4 ENSTSYP00000022732 ENSTSYP00000022732 LOC103277207 LOC103277207 MED4 MED4 ERCC2 ERCC2 GTF2F2 GTF2F2 MED23 MED23 MED26 MED26 MED12 MED12 TAF10 TAF10 CDK20 CDK20 ENSTSYP00000025255 ENSTSYP00000025255 TAF11 TAF11 LOC103262420 LOC103262420 GTF2A1 GTF2A1 MNAT1 MNAT1 ENSTSYP00000026217 ENSTSYP00000026217 ENSTSYP00000027207 ENSTSYP00000027207 ENSTSYP00000027279 ENSTSYP00000027279 ENSTSYP00000027441 ENSTSYP00000027441 ENSTSYP00000027812 ENSTSYP00000027812 MED19 MED19 ENSTSYP00000028885 ENSTSYP00000028885 MED18 MED18 MED17 MED17 MED31 MED31 ENSTSYP00000029577 ENSTSYP00000029577 ENSTSYP00000030172 ENSTSYP00000030172 MED20 MED20 TAF8 TAF8 INTS2 INTS2 TAF6 TAF6 MED1 MED1 MED11 MED11 GTF2A2 GTF2A2 LOC103270356 LOC103270356 MED30 MED30 CCNC CCNC LOC103262367 LOC103262367
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED13LMediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2197 aa)
PLPPR1Phospholipid phosphatase-related protein type 1 isoform X1. (325 aa)
TAF3Transcription initiation factor TFIID subunit 3. (930 aa)
CDK19Cyclin-dependent kinase 19. (501 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (233 aa)
MED10Mediator complex subunit 10. (121 aa)
GTF2H1General transcription factor IIH subunit 1 isoform X1. (548 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1437 aa)
TAF2Transcription initiation factor TFIID subunit 2. (1198 aa)
TAF12Transcription initiation factor TFIID subunit 12. (161 aa)
ENSTSYP00000004911annotation not available (288 aa)
MED22Mediator of RNA polymerase II transcription subunit 22. (200 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (280 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
MED29Mediator of RNA polymerase II transcription subunit 29. (200 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2158 aa)
CDK8Cyclin-dependent kinase 8. (464 aa)
GTF2H3General transcription factor IIH subunit 3 isoform X1. (309 aa)
TAF5Transcription initiation factor TFIID subunit 5. (500 aa)
PLPPR5Phospholipid phosphatase-related protein type 5 isoform X1. (319 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (258 aa)
CDK7Cyclin-dependent kinase 7 isoform X1. (332 aa)
LOC103259463Mediator of RNA polymerase II transcription subunit 30-like isoform X1. (162 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
TAF4BTranscription initiation factor TFIID subunit 4B. (831 aa)
GTF2BTranscription initiation factor IIB. (316 aa)
CCNHcyclin-H; Belongs to the cyclin family. (232 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
TAF7LTranscription initiation factor TFIID subunit 7-like. (467 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
MED12LMediator of RNA polymerase II transcription subunit 12-like protein. (2103 aa)
FBXW12F-box/WD repeat-containing protein 12. (465 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (223 aa)
PLPPR4Phospholipid phosphatase-related protein type 4. (763 aa)
LOC103251355LOW QUALITY PROTEIN: uroplakin-3b-like protein. (209 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (781 aa)
GTF2E1General transcription factor IIE subunit 1. (438 aa)
PLPPR2Phospholipid phosphatase-related protein type 2 isoform X1. (450 aa)
MED25Mediator of RNA polymerase II transcription subunit 25. (724 aa)
TAF13Transcription initiation factor TFIID subunit 13. (86 aa)
ENSTSYP00000017951annotation not available (499 aa)
ENSTSYP00000018417annotation not available (93 aa)
GTF2A1LTFIIA-alpha and beta-like factor isoform X1. (472 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa)
MED24Mediator of RNA polymerase II transcription subunit 24 isoform X2. (1013 aa)
MED28Mediator of RNA polymerase II transcription subunit 28. (178 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (780 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (147 aa)
ENSTSYP00000021098annotation not available (276 aa)
TAF1Transcription initiation factor TFIID subunit. (1925 aa)
TAF4Transcription initiation factor TFIID subunit 4. (631 aa)
ENSTSYP00000022732annotation not available (65 aa)
LOC103277207Transcription initiation factor IIA subunit 1-like. (58 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
ERCC2LOW QUALITY PROTEIN: TFIIH basal transcription factor complex helicase XPD subunit. (668 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
MED23Mediator of RNA polymerase II transcription subunit 23 isoform X2. (1368 aa)
MED26Mediator of RNA polymerase II transcription subunit 26. (596 aa)
MED12Mediator of RNA polymerase II transcription subunit 12 isoform X1. (2127 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (215 aa)
CDK20Cyclin-dependent kinase 20 isoform X1. (288 aa)
ENSTSYP00000025255annotation not available (253 aa)
TAF11Transcription initiation factor TFIID subunit 11 isoform X1. (211 aa)
LOC103262420Mediator of RNA polymerase II transcription subunit 27 isoform X1. (160 aa)
GTF2A1Transcription initiation factor IIA subunit 1. (216 aa)
MNAT1CDK-activating kinase assembly factor MAT1. (169 aa)
ENSTSYP00000026217annotation not available (167 aa)
ENSTSYP00000027207annotation not available (99 aa)
ENSTSYP00000027279annotation not available (208 aa)
ENSTSYP00000027441annotation not available (357 aa)
ENSTSYP00000027812annotation not available (64 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
ENSTSYP00000028885annotation not available (267 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (567 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
ENSTSYP00000029577annotation not available (95 aa)
ENSTSYP00000030172annotation not available (239 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (212 aa)
TAF8Transcription initiation factor TFIID subunit 8 isoform X2. (312 aa)
INTS2Integrator complex subunit 2 isoform X1. (1218 aa)
TAF6Transcription initiation factor TFIID subunit 6. (644 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
LOC103270356General transcription factor IIH subunit. (395 aa)
MED30Mediator of RNA polymerase II transcription subunit 30 isoform X1. (177 aa)
CCNCcyclin-C isoform X1; Belongs to the cyclin family. (283 aa)
LOC103262367Mediator of RNA polymerase II transcription subunit 27-like. (145 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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