(15 nodes) Exon-exon junction complex, and Est1/Ebs1-like network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMG7	Protein SMG7 isoform X3. (1177 aa)
	CASC3	Protein CASC3. (703 aa)
	SMG6	Telomerase-binding protein EST1A isoform X1. (1419 aa)
	SMG5	Protein SMG5 isoform X1. (1017 aa)
	ZGRF1	Protein ZGRF1. (2113 aa)
	SRRM1	Serine/arginine repetitive matrix protein 1 isoform X1. (913 aa)
	LOC103267487	Protein mago nashi homolog isoform X1. (148 aa)
	UPF2	Regulator of nonsense transcripts 2. (1271 aa)
	UPF3A	UPF3A regulator of nonsense mediated mRNA decay. (361 aa)
	UPF1	Regulator of nonsense transcripts 1. (1129 aa)
	UPF3B	Regulator of nonsense transcripts 3B isoform X2. (468 aa)
	EIF4A3	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
	ENSTSYP00000028851	annotation not available (245 aa)
	RBM8A	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
	SMG1	Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family. (3611 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASC3	EIF4A3	ENSTSYP00000002744	ENSTSYP00000028101	Protein CASC3.	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.	0.999
CASC3	ENSTSYP00000028851	ENSTSYP00000002744	ENSTSYP00000028851	Protein CASC3.	annotation not available	0.804
CASC3	LOC103267487	ENSTSYP00000002744	ENSTSYP00000009522	Protein CASC3.	Protein mago nashi homolog isoform X1.	0.985
CASC3	RBM8A	ENSTSYP00000002744	ENSTSYP00000032729	Protein CASC3.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.999
CASC3	SMG1	ENSTSYP00000002744	ENSTSYP00000032795	Protein CASC3.	Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family.	0.480
CASC3	SMG5	ENSTSYP00000002744	ENSTSYP00000003747	Protein CASC3.	Protein SMG5 isoform X1.	0.687
CASC3	SMG6	ENSTSYP00000002744	ENSTSYP00000003134	Protein CASC3.	Telomerase-binding protein EST1A isoform X1.	0.867
CASC3	SMG7	ENSTSYP00000002744	ENSTSYP00000002471	Protein CASC3.	Protein SMG7 isoform X3.	0.672
CASC3	SRRM1	ENSTSYP00000002744	ENSTSYP00000006262	Protein CASC3.	Serine/arginine repetitive matrix protein 1 isoform X1.	0.753
CASC3	UPF1	ENSTSYP00000002744	ENSTSYP00000017119	Protein CASC3.	Regulator of nonsense transcripts 1.	0.997
CASC3	UPF2	ENSTSYP00000002744	ENSTSYP00000015331	Protein CASC3.	Regulator of nonsense transcripts 2.	0.969
CASC3	UPF3A	ENSTSYP00000002744	ENSTSYP00000016505	Protein CASC3.	UPF3A regulator of nonsense mediated mRNA decay.	0.996
CASC3	UPF3B	ENSTSYP00000002744	ENSTSYP00000022703	Protein CASC3.	Regulator of nonsense transcripts 3B isoform X2.	0.998
CASC3	ZGRF1	ENSTSYP00000002744	ENSTSYP00000006193	Protein CASC3.	Protein ZGRF1.	0.972
EIF4A3	CASC3	ENSTSYP00000028101	ENSTSYP00000002744	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.	Protein CASC3.	0.999
EIF4A3	ENSTSYP00000028851	ENSTSYP00000028101	ENSTSYP00000028851	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.	annotation not available	0.992
EIF4A3	LOC103267487	ENSTSYP00000028101	ENSTSYP00000009522	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.	Protein mago nashi homolog isoform X1.	0.989
EIF4A3	RBM8A	ENSTSYP00000028101	ENSTSYP00000032729	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.999
EIF4A3	SMG1	ENSTSYP00000028101	ENSTSYP00000032795	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.	Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family.	0.993
EIF4A3	SMG5	ENSTSYP00000028101	ENSTSYP00000003747	Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.	Protein SMG5 isoform X1.	0.788