(12 nodes) Clathrin adaptor complex network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AP1B1	AP complex subunit beta. (949 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
	AP4E1	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. (1134 aa)
	AP4B1	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
	AP1G2	AP-1 complex subunit gamma. (785 aa)
	AP1S3	AP-1 complex subunit sigma-3. (154 aa)
	AP1S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (159 aa)
	AP1M1	AP-1 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family. (436 aa)
	AP4S1	AP-4 complex subunit sigma-1 isoform X2. (163 aa)
	AP4M1	AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (402 aa)
	AP1M2	AP-1 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (409 aa)
	AP1G1	AP-1 complex subunit gamma. (847 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1B1	AP1G1	ENSTSYP00000001911	ENSTSYP00000026944	AP complex subunit beta.	AP-1 complex subunit gamma.	0.998
AP1B1	AP1G2	ENSTSYP00000001911	ENSTSYP00000006198	AP complex subunit beta.	AP-1 complex subunit gamma.	0.995
AP1B1	AP1M1	ENSTSYP00000001911	ENSTSYP00000017771	AP complex subunit beta.	AP-1 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family.	0.992
AP1B1	AP1M2	ENSTSYP00000001911	ENSTSYP00000022647	AP complex subunit beta.	AP-1 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.	0.992
AP1B1	AP1S1	ENSTSYP00000001911	ENSTSYP00000014701	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.996
AP1B1	AP1S2	ENSTSYP00000001911	ENSTSYP00000004843	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.993
AP1B1	AP1S3	ENSTSYP00000001911	ENSTSYP00000007986	AP complex subunit beta.	AP-1 complex subunit sigma-3.	0.994
AP1B1	AP4B1	ENSTSYP00000001911	ENSTSYP00000005993	AP complex subunit beta.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.738
AP1B1	AP4E1	ENSTSYP00000001911	ENSTSYP00000005356	AP complex subunit beta.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.982
AP1B1	AP4M1	ENSTSYP00000001911	ENSTSYP00000019477	AP complex subunit beta.	AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.973
AP1B1	AP4S1	ENSTSYP00000001911	ENSTSYP00000019170	AP complex subunit beta.	AP-4 complex subunit sigma-1 isoform X2.	0.932
AP1G1	AP1B1	ENSTSYP00000026944	ENSTSYP00000001911	AP-1 complex subunit gamma.	AP complex subunit beta.	0.998
AP1G1	AP1G2	ENSTSYP00000026944	ENSTSYP00000006198	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.886
AP1G1	AP1M1	ENSTSYP00000026944	ENSTSYP00000017771	AP-1 complex subunit gamma.	AP-1 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family.	0.993
AP1G1	AP1M2	ENSTSYP00000026944	ENSTSYP00000022647	AP-1 complex subunit gamma.	AP-1 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.	0.993
AP1G1	AP1S1	ENSTSYP00000026944	ENSTSYP00000014701	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.995
AP1G1	AP1S2	ENSTSYP00000026944	ENSTSYP00000004843	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.994
AP1G1	AP1S3	ENSTSYP00000026944	ENSTSYP00000007986	AP-1 complex subunit gamma.	AP-1 complex subunit sigma-3.	0.996
AP1G1	AP4B1	ENSTSYP00000026944	ENSTSYP00000005993	AP-1 complex subunit gamma.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.979
AP1G1	AP4E1	ENSTSYP00000026944	ENSTSYP00000005356	AP-1 complex subunit gamma.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.740