(5 nodes) Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	PLCB3	Phosphoinositide phospholipase C. (828 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1094 aa)
	GNA15	Guanine nucleotide-binding protein subunit alpha-15. (250 aa)
	ENSTSYP00000032761	annotation not available (68 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTSYP00000032761	GNA15	ENSTSYP00000032761	ENSTSYP00000032061	annotation not available	Guanine nucleotide-binding protein subunit alpha-15.	0.827
ENSTSYP00000032761	GNAQ	ENSTSYP00000032761	ENSTSYP00000008426	annotation not available	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.773
ENSTSYP00000032761	PLCB2	ENSTSYP00000032761	ENSTSYP00000026358	annotation not available	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.799
ENSTSYP00000032761	PLCB3	ENSTSYP00000032761	ENSTSYP00000020180	annotation not available	Phosphoinositide phospholipase C.	0.776
GNA15	ENSTSYP00000032761	ENSTSYP00000032061	ENSTSYP00000032761	Guanine nucleotide-binding protein subunit alpha-15.	annotation not available	0.827
GNA15	GNAQ	ENSTSYP00000032061	ENSTSYP00000008426	Guanine nucleotide-binding protein subunit alpha-15.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.795
GNA15	PLCB2	ENSTSYP00000032061	ENSTSYP00000026358	Guanine nucleotide-binding protein subunit alpha-15.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.924
GNA15	PLCB3	ENSTSYP00000032061	ENSTSYP00000020180	Guanine nucleotide-binding protein subunit alpha-15.	Phosphoinositide phospholipase C.	0.909
GNAQ	ENSTSYP00000032761	ENSTSYP00000008426	ENSTSYP00000032761	Guanine nucleotide-binding protein G(Q) subunit alpha.	annotation not available	0.773
GNAQ	GNA15	ENSTSYP00000008426	ENSTSYP00000032061	Guanine nucleotide-binding protein G(Q) subunit alpha.	Guanine nucleotide-binding protein subunit alpha-15.	0.795
GNAQ	PLCB2	ENSTSYP00000008426	ENSTSYP00000026358	Guanine nucleotide-binding protein G(Q) subunit alpha.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.907
GNAQ	PLCB3	ENSTSYP00000008426	ENSTSYP00000020180	Guanine nucleotide-binding protein G(Q) subunit alpha.	Phosphoinositide phospholipase C.	0.940
PLCB2	ENSTSYP00000032761	ENSTSYP00000026358	ENSTSYP00000032761	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	annotation not available	0.799
PLCB2	GNA15	ENSTSYP00000026358	ENSTSYP00000032061	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Guanine nucleotide-binding protein subunit alpha-15.	0.924
PLCB2	GNAQ	ENSTSYP00000026358	ENSTSYP00000008426	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.907
PLCB2	PLCB3	ENSTSYP00000026358	ENSTSYP00000020180	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Phosphoinositide phospholipase C.	0.860
PLCB3	ENSTSYP00000032761	ENSTSYP00000020180	ENSTSYP00000032761	Phosphoinositide phospholipase C.	annotation not available	0.776
PLCB3	GNA15	ENSTSYP00000020180	ENSTSYP00000032061	Phosphoinositide phospholipase C.	Guanine nucleotide-binding protein subunit alpha-15.	0.909
PLCB3	GNAQ	ENSTSYP00000020180	ENSTSYP00000008426	Phosphoinositide phospholipase C.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.940
PLCB3	PLCB2	ENSTSYP00000020180	ENSTSYP00000026358	Phosphoinositide phospholipase C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.860