(50 nodes) Glycosaminoglycan degradation, and Glycolipid catabolic process network (Carlito syrichta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HPSE	Heparanase. (499 aa)
	HPSE2	Inactive heparanase-2. (592 aa)
	HEXA	Beta-hexosaminidase. (532 aa)
	NEU1	Sialidase-1. (417 aa)
	ARSG	Arylsulfatase G. (525 aa)
	ARSA	Arylsulfatase A isoform X1. (518 aa)
	NEU3	Sialidase-3. (454 aa)
	ARSH	Arylsulfatase H. (565 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (901 aa)
	HGSNAT	LOW QUALITY PROTEIN: heparan-alpha-glucosaminide N-acetyltransferase. (295 aa)
	CPVL	Probable serine carboxypeptidase CPVL; Belongs to the peptidase S10 family. (272 aa)
	GLB1L2	Beta-galactosidase. (636 aa)
	LOC103272462	Biorientation of chromosomes in cell division protein 1-like. (147 aa)
	GLA	Alpha-galactosidase. (429 aa)
	UGT8	2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Belongs to the UDP-glycosyltransferase family. (541 aa)
	SUMF1	Sulfatase-modifying factor 1 isoform X1. (373 aa)
	ALPK3	Alpha-protein kinase 3. (1640 aa)
	A4GNT	alpha-1,4-N-acetylglucosaminyltransferase. (341 aa)
	GLB1L	Beta-galactosidase-1-like protein; Belongs to the glycosyl hydrolase 35 family. (648 aa)
	GNS	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (568 aa)
	SGSH	N-sulphoglucosamine sulphohydrolase. (502 aa)
	ARSK	Arylsulfatase K. (536 aa)
	GLB1L3	Galactosidase beta 1 like 3. (652 aa)
	NEU4	Sialidase-4. (480 aa)
	HYAL1	Hyaluronidase. (435 aa)
	GAL3ST4	galactose-3-O-sulfotransferase 4. (486 aa)
	GALC	Galactocerebrosidase isoform X1. (685 aa)
	B4GALT6	Beta-1,4-galactosyltransferase 6 isoform X2. (382 aa)
	HYAL3	Hyaluronidase. (424 aa)
	ARSB	Arylsulfatase B. (488 aa)
	GUSB	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (624 aa)
	GLB1	Beta-galactosidase. (677 aa)
	LOC103265637	Biorientation of chromosomes in cell division protein 1. (217 aa)
	SUMF2	Sulfatase-modifying factor 2 isoform X1. (320 aa)
	GALNS	N-acetylgalactosamine-6-sulfatase. (515 aa)
	SULF2	Extracellular sulfatase Sulf-2 isoform X2. (788 aa)
	MANBA	Beta-mannosidase. (820 aa)
	IDS	Iduronate 2-sulfatase isoform X1. (550 aa)
	IDUA	alpha-L-iduronidase. (541 aa)
	CTSA	Carboxypeptidase; Belongs to the peptidase S10 family. (475 aa)
	HEXB	Beta-hexosaminidase subunit beta. (452 aa)
	ARSJ	Arylsulfatase J. (599 aa)
	ARSI	Arylsulfatase I. (535 aa)
	NAGLU	alpha-N-acetylglucosaminidase. (724 aa)
	TMEM130	Transmembrane protein 130. (435 aa)
	ARSE	Arylsulfatase E isoform X1. (599 aa)
	NEU2	Sialidase-2. (378 aa)
	BOD1L1	Biorientation of chromosomes in cell division protein 1-like 1. (3052 aa)
	NAGA	Alpha-galactosidase. (411 aa)
	GAL3ST1	Galactosylceramide sulfotransferase. (424 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4GNT	B4GALT6	ENSTSYP00000009416	ENSTSYP00000017254	alpha-1,4-N-acetylglucosaminyltransferase.	Beta-1,4-galactosyltransferase 6 isoform X2.	0.672
A4GNT	GLA	ENSTSYP00000009416	ENSTSYP00000007146	alpha-1,4-N-acetylglucosaminyltransferase.	Alpha-galactosidase.	0.822
A4GNT	GUSB	ENSTSYP00000009416	ENSTSYP00000019395	alpha-1,4-N-acetylglucosaminyltransferase.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.846
A4GNT	MANBA	ENSTSYP00000009416	ENSTSYP00000024753	alpha-1,4-N-acetylglucosaminyltransferase.	Beta-mannosidase.	0.845
A4GNT	NAGA	ENSTSYP00000009416	ENSTSYP00000033705	alpha-1,4-N-acetylglucosaminyltransferase.	Alpha-galactosidase.	0.822
ALPK3	BOD1L1	ENSTSYP00000008805	ENSTSYP00000031484	Alpha-protein kinase 3.	Biorientation of chromosomes in cell division protein 1-like 1.	0.527
ALPK3	GLB1	ENSTSYP00000008805	ENSTSYP00000019433	Alpha-protein kinase 3.	Beta-galactosidase.	0.420
ALPK3	GLB1L	ENSTSYP00000008805	ENSTSYP00000010775	Alpha-protein kinase 3.	Beta-galactosidase-1-like protein; Belongs to the glycosyl hydrolase 35 family.	0.420
ALPK3	GLB1L2	ENSTSYP00000008805	ENSTSYP00000006471	Alpha-protein kinase 3.	Beta-galactosidase.	0.420
ALPK3	GLB1L3	ENSTSYP00000008805	ENSTSYP00000012898	Alpha-protein kinase 3.	Galactosidase beta 1 like 3.	0.420
ALPK3	LOC103265637	ENSTSYP00000008805	ENSTSYP00000022343	Alpha-protein kinase 3.	Biorientation of chromosomes in cell division protein 1.	0.527
ALPK3	LOC103272462	ENSTSYP00000008805	ENSTSYP00000006920	Alpha-protein kinase 3.	Biorientation of chromosomes in cell division protein 1-like.	0.527
ARSA	ARSB	ENSTSYP00000001907	ENSTSYP00000019190	Arylsulfatase A isoform X1.	Arylsulfatase B.	0.910
ARSA	ARSE	ENSTSYP00000001907	ENSTSYP00000029794	Arylsulfatase A isoform X1.	Arylsulfatase E isoform X1.	0.512
ARSA	ARSG	ENSTSYP00000001907	ENSTSYP00000001791	Arylsulfatase A isoform X1.	Arylsulfatase G.	0.844
ARSA	ARSH	ENSTSYP00000001907	ENSTSYP00000003161	Arylsulfatase A isoform X1.	Arylsulfatase H.	0.516
ARSA	ARSI	ENSTSYP00000001907	ENSTSYP00000027840	Arylsulfatase A isoform X1.	Arylsulfatase I.	0.875
ARSA	ARSJ	ENSTSYP00000001907	ENSTSYP00000027672	Arylsulfatase A isoform X1.	Arylsulfatase J.	0.900
ARSA	ARSK	ENSTSYP00000001907	ENSTSYP00000012631	Arylsulfatase A isoform X1.	Arylsulfatase K.	0.702
ARSA	BOD1L1	ENSTSYP00000001907	ENSTSYP00000031484	Arylsulfatase A isoform X1.	Biorientation of chromosomes in cell division protein 1-like 1.	0.407