STRINGSTRING
LYN LYN VAV3 VAV3 PTPRC PTPRC CD3E CD3E SOS2 SOS2 GRB10 GRB10 PTPN1 PTPN1 ITK ITK CD2AP CD2AP PTPN11 PTPN11 MST1 MST1 CBLB CBLB SOS1 SOS1 INPPL1 INPPL1 PLCG1 PLCG1 PIK3CA PIK3CA MFSD6L MFSD6L SH3KBP1 SH3KBP1 EGFR EGFR GAB1 GAB1 LRIG3 LRIG3 PTPN18 PTPN18 GRAP2 GRAP2 BTK BTK BMX BMX SHC1 SHC1 TXK TXK PAG1 PAG1 LRIG1 LRIG1 RRAS RRAS ZAP70 ZAP70 SH3GL2 SH3GL2 SHC4 SHC4 PLCG2 PLCG2 FGR FGR CD3D CD3D SYK SYK ENSTSYP00000017967 ENSTSYP00000017967 TEC TEC PIK3R1 PIK3R1 LCK LCK CD247 CD247 PIK3CG PIK3CG CSK CSK INSR INSR INSRR INSRR IRS4 IRS4 HCK HCK SHC3 SHC3 SH3GL3 SH3GL3 PTK2 PTK2 PIK3R3 PIK3R3 LAT LAT NTRK1 NTRK1 BLNK BLNK CBLC CBLC MST1R MST1R PIK3R5 PIK3R5 PDGFRB PDGFRB GP6 GP6 PIK3CD PIK3CD CBL CBL LOC103253501 LOC103253501 LOC103271944 LOC103271944 LCP2 LCP2 SH2D2A SH2D2A PTPN2 PTPN2 GRAP GRAP GRB2 GRB2 SRMS SRMS PIK3R6 PIK3R6 PIK3CB PIK3CB SPRY2 SPRY2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LYNTyrosine-protein kinase. (512 aa)
VAV3Guanine nucleotide exchange factor VAV3-like. (514 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C. (601 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (178 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1318 aa)
GRB10Growth factor receptor-bound protein 10 isoform X1. (593 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (434 aa)
ITKTyrosine-protein kinase. (620 aa)
CD2APCD2-associated protein. (638 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
MST1Hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
CBLBE3 ubiquitin-protein ligase CBL-B isoform X1. (983 aa)
SOS1Son of sevenless homolog 1 isoform X2. (441 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1259 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MFSD6LMajor facilitator superfamily domain-containing protein 6-like. (587 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1 isoform X1. (569 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (700 aa)
LRIG3Leucine-rich repeats and immunoglobulin-like domains protein 3. (1096 aa)
PTPN18Tyrosine-protein phosphatase non-receptor type 18. (454 aa)
GRAP2GRB2-related adapter protein 2 isoform X1. (322 aa)
BTKTyrosine-protein kinase. (659 aa)
BMXTyrosine-protein kinase. (653 aa)
SHC1SHC-transforming protein 1 isoform X1. (474 aa)
TXKTyrosine-protein kinase. (524 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (435 aa)
LRIG1Leucine-rich repeats and immunoglobulin-like domains protein 1. (1091 aa)
RRASRas-related protein R-Ras. (218 aa)
ZAP70Tyrosine-protein kinase ZAP-70. (556 aa)
SH3GL2endophilin-A1 isoform X2. (350 aa)
SHC4SHC-transforming protein 4. (629 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
FGRTyrosine-protein kinase. (526 aa)
CD3DT-cell surface glycoprotein CD3 delta chain isoform X1. (171 aa)
SYKTyrosine-protein kinase. (634 aa)
ENSTSYP00000017967annotation not available (148 aa)
TECTyrosine-protein kinase. (631 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
LCKTyrosine-protein kinase. (524 aa)
CD247CD247 molecule. (145 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa)
CSKTyrosine-protein kinase. (450 aa)
INSRTyrosine-protein kinase receptor. (1356 aa)
INSRRTyrosine-protein kinase receptor. (1284 aa)
IRS4Insulin receptor substrate 4. (1159 aa)
HCKTyrosine-protein kinase. (546 aa)
SHC3SHC-transforming protein 3. (107 aa)
SH3GL3endophilin-A3. (289 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2. (461 aa)
LATLinker for activation of T cells. (258 aa)
NTRK1High affinity nerve growth factor receptor. (721 aa)
BLNKB-cell linker protein. (439 aa)
CBLCE3 ubiquitin-protein ligase CBL-C. (337 aa)
MST1RMacrophage-stimulating protein receptor isoform X1. (1405 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (879 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
GP6Platelet glycoprotein VI. (332 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
CBLE3 ubiquitin-protein ligase CBL. (898 aa)
LOC103253501Guanine nucleotide exchange factor VAV3-like. (209 aa)
LOC103271944Proto-oncogene vav. (147 aa)
LCP2Lymphocyte cytosolic protein 2. (532 aa)
SH2D2ASH2 domain-containing protein 2A isoform X1. (398 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
GRAPGRB2-related adapter protein. (188 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
SRMSTyrosine-protein kinase. (424 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6. (757 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
SPRY2Protein sprouty homolog 2. (338 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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